Genetic Support of A Causal Relationship Between Iron Status and Type 2 Diabetes: A Mendelian Randomization Study

Associations between maternal vitamin D status during three trimesters and cord blood 25(OH)D concentrations in newborns: a prospective Shanghai birth cohort study

(2021) Xirui Wang et al.   EUROPEAN JOURNAL OF NUTRITION

Selecting likely causal risk factors from high-throughput experiments using multivariable Mendelian randomization

(2020) Verena Zuber et al.   Nature Communications

Genetic regulatory subnetworks and key regulating genes in rat hippocampus perturbed by prenatal malnutrition: implications for major brain disorders

(2020) Jiaying Chen et al.   Aging-US

Multi-trait analysis for genome-wide association study of five psychiatric disorders

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Common conditions associated with hereditary haemochromatosis genetic variants: cohort study in UK Biobank

(2019) Luke C Pilling et al.   BMJ-British Medical Journal

Sex-specific Association of Circulating Ferritin Levels and Risk of Type 2 Diabetes: A Dose-response Meta-analysis of Prospective Studies

(2019) Li Jiang et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Mendelian randomization analysis using mixture models for robust and efficient estimation of causal effects

(2019) Guanghao Qi et al.   Nature Communications

Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration

(2019) Henry R. Wilman et al.   JOURNAL OF HEPATOLOGY

Associations of genetically determined iron status across the phenome: A mendelian randomization study

(2019) Dipender Gill et al.   PLOS MEDICINE

Immunodeficiency Promotes Adaptive Alterations of Host Gut Microbiome: An Observational Metagenomic Study in Mice

(2019) Shuyu Zheng et al.   Frontiers in Microbiology

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

(2018) Anubha Mahajan et al.   NATURE GENETICS

Iron Status and Risk of Stroke

(2018) Dipender Gill et al.   STROKE

Interpreting findings from Mendelian randomization using the MR-Egger method

(2017) Stephen Burgess et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the KidneyNovelty and Significance

(2017) Louise V. Wain et al.   HYPERTENSION

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis

(2017) Eleanor Wheeler et al.   PLOS MEDICINE

PhenoScanner: a database of human genotype–phenotype associations

(2016) James R. Staley et al.   BIOINFORMATICS

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator

(2016) Jack Bowden et al.   GENETIC EPIDEMIOLOGY

Mendelian Randomization using Public Data from Genetic Consortia

(2016) John R. Thompson et al.  

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

(2016) Praveen Surendran et al.   NATURE GENETICS

Mendelian Randomization using Public Data from Genetic Consortia

(2016) John R. Thompson et al.   International Journal of Biostatistics

Using published data in Mendelian randomization: a blueprint for efficient identification of causal risk factors

(2015) Stephen Burgess et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Obesity and iron deficiency: a quantitative meta-analysis

(2015) L. Zhao et al.   Obesity Reviews

Combining information on multiple instrumental variables in Mendelian randomization: comparison of allele score and summarized data methods

(2015) Stephen Burgess et al.   STATISTICS IN MEDICINE

Heme Oxygenase-1 Drives Metaflammation and Insulin Resistance in Mouse and Man

(2014) Alexander Jais et al.   CELL

Pleiotropic actions of iron balance in diabetes mellitus

(2014) Xinhui Wang et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis

(2014) Beben Benyamin et al.   Nature Communications

Iron and Diabetes Risk

(2013) Judith A. Simcox et al.   Cell Metabolism

Ferritin levels and risk of type 2 diabetes mellitus: an updated systematic review and meta-analysis of prospective evidence

(2013) Setor K. Kunutsor et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Association of iron indices and type 2 diabetes: a meta-analysis of observational studies

(2013) Ester Orban et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Mendelian randomization in health research: Using appropriate genetic variants and avoiding biased estimates

(2013) Amy E. Taylor et al.   Economics & Human Biology

Iron regulates glucose homeostasis in liver and muscle via AMP-activated protein kinase in mice

(2013) Jingyu Huang et al.   FASEB JOURNAL

Serum ferritin is associated with non-alcoholic fatty liver disease and decreased Β-cell function in non-diabetic men and women

(2013) Kristina M. Utzschneider et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Discovery and refinement of loci associated with lipid levels

(2013) Cristen J Willer et al.   NATURE GENETICS

Serum Iron Levels and the Risk of Parkinson Disease: A Mendelian Randomization Study

(2013) Irene Pichler et al.   PLOS MEDICINE

Association of TMPRSS6 polymorphisms with ferritin, hemoglobin, and type 2 diabetes risk in a Chinese Han population

(2012) Wei Gan et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Dietary iron intake, body iron stores, and the risk of type 2 diabetes: a systematic review and meta-analysis

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TMPRSS6, but not TF, TFR2 or BMP2 variants are associated with increased risk of iron-deficiency anemia

(2012) Peng An et al.   HUMAN MOLECULAR GENETICS

Adipocyte iron regulates adiponectin and insulin sensitivity

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Body Iron Stores and Heme-Iron Intake in Relation to Risk of Type 2 Diabetes: A Systematic Review and Meta-Analysis

(2012) Zhuoxian Zhao et al.   PLoS One

Genetic Determinants for Body Iron Store and Type 2 Diabetes Risk in US Men and Women

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The many faces of pleiotropy

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Hepcidin and iron regulation, 10 years later

(2011) T. Ganz   BLOOD

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

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The relationship between obesity and hypoferraemia in adults: a systematic review

(2011) H. L. Cheng et al.   Obesity Reviews

Using multiple genetic variants as instrumental variables for modifiable risk factors

(2011) Tom M Palmer et al.   STATISTICAL METHODS IN MEDICAL RESEARCH

Common Variants at 10 Genomic Loci Influence Hemoglobin A1C Levels via Glycemic and Nonglycemic Pathways

(2010) N. Soranzo et al.   DIABETES

Hypoxia-inducible factor-1α regulates β cell function in mouse and human islets

(2010) Kim Cheng et al.   JOURNAL OF CLINICAL INVESTIGATION

Assumptions of IV Methods for Observational Epidemiology

(2010) Vanessa Didelez et al.   STATISTICAL SCIENCE

Mendelian Randomization: How It Can--and Cannot--Help Confirm Causal Relations between Nutrition and Cancer

(2009) A. Schatzkin et al.   Cancer Prevention Research

Forging a field: the golden age of iron biology

(2008) N. C. Andrews   BLOOD

Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)

(2008) Karin E Finberg et al.   NATURE GENETICS

Mendelian Randomisation and Causal Inference in Observational Epidemiology

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