Amyloid-β disrupts unitary calcium entry through endothelial NMDA receptors in mouse cerebral arteries

Multifaceted roles of pericytes in central nervous system homeostasis and disease

(2020) Zhitong Zheng et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research*

(2020) Nathalie Percie du Sert et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Regulation of blood–brain barrier integrity by microglia in health and disease: A therapeutic opportunity

(2020) Patrick T Ronaldson et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

tPA Deficiency Underlies Neurovascular Coupling Dysfunction by Amyloid-β

(2020) Laibaik Park et al.   JOURNAL OF NEUROSCIENCE

Calcium signals that determine vascular resistance

(2019) Matteo Ottolini et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Endothelial NMDA receptors mediate activity-dependent brain hemodynamic responses in mice

(2019) Adam D. Hogan-Cann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PDGFR-β restores blood-brain barrier functions in a mouse model of focal cerebral ischemia

(2018) Jie Shen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders

(2018) Melanie D. Sweeney et al.   Nature Reviews Neurology

Neuroprotective effects of TRPA1 channels in the cerebral endothelium following ischemic stroke

(2018) Paulo Wagner Pires et al.   eLife

Involvement of caveolin-1 in neurovascular unit remodeling after stroke: Effects on neovascularization and astrogliosis

(2018) Camille Blochet et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Astrocytes drive cortical vasodilatory signaling by activating endothelial NMDA receptors

(2017) Lingling Lu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The angiotensin II receptor type 1b is the primary sensor of intraluminal pressure in cerebral artery smooth muscle cells

(2017) Paulo W. Pires et al.   JOURNAL OF PHYSIOLOGY-LONDON

The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease

(2017) Costantino Iadecola   NEURON

Vascular Risk Factors: Imaging and Neuropathologic Correlates

(2017) David S. Knopman et al.   JOURNAL OF ALZHEIMERS DISEASE

Physiological Roles of Non-Neuronal NMDA Receptors

(2016) Adam D. Hogan-Cann et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Regulation of myogenic tone and structure of parenchymal arterioles by hypertension and the mineralocorticoid receptor

(2015) Paulo W. Pires et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Unitary TRPV3 channel Ca2+ influx events elicit endothelium-dependent dilation of cerebral parenchymal arterioles

(2015) Paulo W. Pires et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Allosteric modulators of NMDA receptors: multiple sites and mechanisms

(2015) Shujia Zhu et al.   CURRENT OPINION IN PHARMACOLOGY

Vascular Inward Rectifier K+Channels as External K+Sensors in the Control of Cerebral Blood Flow

(2015) Thomas A. Longden et al.   MICROCIRCULATION

Transient Receptor Potential Channels in the Vasculature

(2015) Scott Earley et al.   PHYSIOLOGICAL REVIEWS

Localized TRPA1 channel Ca2+signals stimulated by reactive oxygen species promote cerebral artery dilation

(2015) Michelle N. Sullivan et al.   Science Signaling

Localized TRPA1 channel Ca2+signals stimulated by reactive oxygen species promote cerebral artery dilation

(2015) Michelle N. Sullivan et al.   Science Signaling

Isoform- and Species-specific Control of Inositol 1,4,5-Trisphosphate (IP3) Receptors by Reactive Oxygen Species

(2014) Száva Bánsághi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decoding dynamic Ca2+ signaling in the vascular endothelium

(2014) Mark S. Taylor et al.   Frontiers in Physiology

Endothelial TRPV4 channels mediate dilation of cerebral arteries: impairment and recovery in cerebrovascular pathologies related to Alzheimer's disease

(2013) Luqing Zhang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Blood–Brain Barrier Dysfunction as a Cause and Consequence of Alzheimer's Disease

(2013) Michelle A Erickson et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Diversity in Mechanisms of Endothelium-Dependent Vasodilation in Health and Disease

(2013) Matthew J. Durand et al.   MICROCIRCULATION

NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease

(2013) Pierre Paoletti et al.   NATURE REVIEWS NEUROSCIENCE

Influence of GluN2 subunit identity on NMDA receptor function

(2013) D.J.A. Wyllie et al.   NEUROPHARMACOLOGY

Astrocyte-induced cortical vasodilation is mediated by D-serine and endothelial nitric oxide synthase

(2013) J. L. L. Stobart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRPV4 channels stimulate Ca2+-induced Ca2+ release in astrocytic endfeet and amplify neurovascular coupling responses

(2013) K. M. Dunn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deficiency in Mural Vascular Cells Coincides with Blood-Brain Barrier Disruption in Alzheimer's Disease

(2012) Jesse D. Sengillo et al.   BRAIN PATHOLOGY

Function and expression of ryanodine receptors and inositol 1,4,5-trisphosphate receptors in smooth muscle cells of murine feed arteries and arterioles

(2012) Erika B. Westcott et al.   JOURNAL OF PHYSIOLOGY-LONDON

Recruitment of Dynamic Endothelial Ca2+Signals by the TRPA1 Channel Activator AITC in Rat Cerebral Arteries

(2012) Xun Qian et al.   MICROCIRCULATION

Elementary Ca2+ Signals Through Endothelial TRPV4 Channels Regulate Vascular Function

(2012) S. K. Sonkusare et al.   SCIENCE

Amyloid Beta Induces Oxidative Stress-Mediated Blood–Brain Barrier Changes in Capillary Amyloid Angiopathy

(2011) Anna Carrano et al.   ANTIOXIDANTS & REDOX SIGNALING

Coactivation of NMDA Receptors by Glutamate and d-Serine Induces Dilation of Isolated Middle Cerebral Arteries

(2011) Jillian L LeMaistre et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid- 

(2011) L. Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-definition characterization of cerebral β-amyloid angiopathy in Alzheimer's disease

(2010) Virawudh Soontornniyomkij et al.   HUMAN PATHOLOGY

Amyloid-β Protein Oligomer at Low Nanomolar Concentrations Activates Microglia and Induces Microglial Neurotoxicity

(2010) Izumi Maezawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endothelial SKCa and IKCa Channels Regulate Brain Parenchymal Arteriolar Diameter and Cortical Cerebral Blood Flow

(2010) Rachael M Hannah et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Epoxyeicosatrienoic acids and endothelium-dependent responses

(2010) William B. Campbell et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

IP3 Receptors: Toward Understanding Their Activation

(2010) C. W. Taylor et al.   Cold Spring Harbor Perspectives in Biology

Endothelium-Dependent Cerebral Artery Dilation Mediated by TRPA1 and Ca 2+ -Activated K + Channels

(2009) Scott Earley et al.   CIRCULATION RESEARCH

Vascular amyloid alters astrocytic water and potassium channels in mouse models and humans with Alzheimer's disease

(2009) D.M. Wilcock et al.   NEUROSCIENCE