Molecular models of LINC complex assembly at the nuclear envelope

A molecular mechanism for LINC complex branching by structurally diverse SUN-KASH 6:6 assemblies

(2021) Manickam Gurusaran et al.   eLife

The testis-specific LINC component SUN3 is essential for sperm head shaping during mouse spermiogenesis

(2020) Qian Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural analysis of different LINC complexes reveals distinct binding modes

(2020) Victor E. Cruz et al.   JOURNAL OF MOLECULAR BIOLOGY

SUN/KASH interactions facilitate force transmission across the nuclear envelope

(2019) Hongyan Hao et al.   Nucleus

Role of KASH domain lengths in the regulation of LINC complexes

(2019) Zeinab Jahed et al.   MOLECULAR BIOLOGY OF THE CELL

The nucleus feels the force, LINCed in or not!

(2019) Zeinab Jahed et al.   CURRENT OPINION IN CELL BIOLOGY

Structural conservation of the autoinhibitory domain in SUN proteins

(2018) Yang Xu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular Insights into the Mechanisms of SUN1 Oligomerization in the Nuclear Envelope

(2018) Zeinab Jahed et al.   BIOPHYSICAL JOURNAL

Experience-Dependent Plasticity of Odor Representations in the Telencephalon of Zebrafish

(2018) Gilad A. Jacobson et al.   CURRENT BIOLOGY

Jaw1/LRMP has a role in maintaining nuclear shape via interaction with SUN proteins

(2018) Takuma Kozono et al.   JOURNAL OF BIOCHEMISTRY

Fluorescence fluctuation spectroscopy reveals differential SUN protein oligomerization in living cells

(2018) Jared Hennen et al.   MOLECULAR BIOLOGY OF THE CELL

A Molecular Model for LINC complex regulation: Activation of SUN2 for KASH binding

(2018) Zeinab Jahed et al.   MOLECULAR BIOLOGY OF THE CELL

The LINC and NPC relationship – it's complicated!

(2016) Zeinab Jahed et al.   JOURNAL OF CELL SCIENCE

Coiled-Coil Domains of SUN Proteins as Intrinsic Dynamic Regulators

(2016) Si Nie et al.   STRUCTURE

A Disulfide Bond Is Required for the Transmission of Forces through SUN-KASH Complexes

(2015) Zeinab Jahed et al.   BIOPHYSICAL JOURNAL

SUN4 is essential for nuclear remodeling during mammalian spermiogenesis

(2015) Alessandra Calvi et al.   DEVELOPMENTAL BIOLOGY

Accessorizing and anchoring the LINC complex for multifunctionality

(2015) Wakam Chang et al.   JOURNAL OF CELL BIOLOGY

KASHing up with the nucleus: novel functional roles of KASH proteins at the cytoplasmic surface of the nucleus

(2014) GW Gant Luxton et al.   CURRENT OPINION IN CELL BIOLOGY

Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells

(2014) M. H. Wilson et al.   DEVELOPMENT

The Caenorhabditis elegans SUN protein UNC-84 interacts with lamin to transfer forces from the cytoplasm to the nucleoskeleton during nuclear migration

(2014) Courtney R. Bone et al.   MOLECULAR BIOLOGY OF THE CELL

The diverse functional LINCs of the nuclear envelope to the cytoskeleton and chromatin

(2013) Andrea Rothballer et al.   CHROMOSOMA

Structural insights into LINC complexes

(2013) Brian A Sosa et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Nesprins: from the nuclear envelope and beyond

(2013) Dipen Rajgor et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

A mammalian KASH domain protein coupling meiotic chromosomes to the cytoskeleton

(2013) Henning F. Horn et al.   JOURNAL OF CELL BIOLOGY

Poring over pores: nuclear pore complex insertion into the nuclear envelope

(2013) Andrea Rothballer et al.   TRENDS IN BIOCHEMICAL SCIENCES

Destination: inner nuclear membrane

(2013) Santharam S. Katta et al.   TRENDS IN CELL BIOLOGY

LINC Complexes Form by Binding of Three KASH Peptides to Domain Interfaces of Trimeric SUN Proteins

(2012) Brian A. Sosa et al.   CELL

Structural insights into SUN-KASH complexes across the nuclear envelope

(2012) Wenjia Wang et al.   CELL RESEARCH

A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis

(2012) Akihiro Morimoto et al.   JOURNAL OF CELL BIOLOGY

Multiple Novel Nesprin-1 and Nesprin-2 Variants Act as Versatile Tissue-Specific Intracellular Scaffolds

(2012) Dipen Rajgor et al.   PLoS One

Structure of Sad1-UNC84 Homology (SUN) Domain Defines Features of Molecular Bridge in Nuclear Envelope

(2011) Zhaocai Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Interaction between Nesprins and Sun Proteins at the Nuclear Envelope Is Critical for Force Transmission between the Nucleus and Cytoskeleton

(2011) Maria L. Lombardi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple mechanisms actively target the SUN protein UNC-84 to the inner nuclear membrane

(2011) Erin C. Tapley et al.   MOLECULAR BIOLOGY OF THE CELL

Molecular mechanisms of centrosome and cytoskeleton anchorage at the nuclear envelope

(2010) Maria Schneider et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Lrmp/Jaw1 is Expressed in Sweet, Bitter, and Umami Receptor-Expressing Cells

(2010) Y. Shindo et al.   CHEMICAL SENSES

UNC-83 coordinates kinesin-1 and dynein activities at the nuclear envelope during nuclear migration

(2009) Heidi N. Fridolfsson et al.   DEVELOPMENTAL BIOLOGY

Mammalian SUN Protein Interaction Networks at the Inner Nuclear Membrane and Their Role in Laminopathy Disease Processes

(2009) Farhana Haque et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bringing KASH under the SUN: the many faces of nucleo-cytoskeletal connections

(2009) David Razafsky et al.   JOURNAL OF CELL BIOLOGY

Nesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarization

(2009) K. J. Roux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sun1 forms immobile macromolecular assemblies at the nuclear envelope

(2008) Wenshu Lu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Dysfunctional Connections Between the Nucleus and the Actin and Microtubule Networks in Laminopathic Models

(2008) Christopher M. Hale et al.   BIOPHYSICAL JOURNAL