The role of Mfn2 in the structure and function of endoplasmic reticulum-mitochondrial tethering in vivo

Mfn2 Ablation in the Adult Mouse Hippocampus and Cortex Causes Neuronal Death

(2020) Song Han et al.   Cells

Mitochondria-Endoplasmic Reticulum Contacts in Reactive Astrocytes Promote Vascular Remodeling

(2020) Jana Gӧbel et al.   Cell Metabolism

Mitochondria dysfunction in the pathogenesis of Alzheimer’s disease: recent advances

(2020) Wenzhang Wang et al.   Molecular Neurodegeneration

Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease

(2019) María Isabel Hernández-Alvarez et al.   CELL

DJ-1 regulates the integrity and function of ER-mitochondria association through interaction with IP3R3-Grp75-VDAC1

(2019) Yi Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mul1 restrains Parkin-mediated mitophagy in mature neurons by maintaining ER-mitochondrial contacts

(2019) Rajat Puri et al.   Nature Communications

Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex

(2018) Sirui Jiang et al.   Molecular Neurodegeneration

Mitochondria-associated membranes in aging and senescence: structure, function, and dynamics

(2018) Justyna Janikiewicz et al.   Cell Death & Disease

Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy

(2018) Gian-Luca McLelland et al.   eLife

Endoplasmic reticulum-mitochondria tethering in neurodegenerative diseases

(2017) Yi Liu et al.   Translational Neurodegeneration

The coming of age of the mitochondria–ER contact: a matter of thickness

(2016) M Giacomello et al.   CELL DEATH AND DIFFERENTIATION

Critical reappraisal confirms that Mitofusin 2 is an endoplasmic reticulum–mitochondria tether

(2016) Deborah Naon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Presenilin 2 Modulates Endoplasmic Reticulum-Mitochondria Coupling by Tuning the Antagonistic Effect of Mitofusin 2

(2016) Riccardo Filadi et al.   Cell Reports

Mitofusin-2-mediated tethering of mitochondria and endoplasmic reticulum promotes cell cycle arrest of vascular smooth muscle cells in G0/G1 phase

(2015) D. Li et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Dysfunction in endoplasmic reticulum-mitochondria crosstalk underlies SIGMAR1 loss of function mediated motor neuron degeneration

(2015) Nathalie Bernard-Marissal et al.   BRAIN

Distinct mechanisms controlling rough and smooth endoplasmic reticulum contacts with mitochondria

(2015) P. T. C. Wang et al.   JOURNAL OF CELL SCIENCE

MFN2-related neuropathies: Clinical features, molecular pathogenesis and therapeutic perspectives

(2015) Giulia Stuppia et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Mitofusin 2 ablation increases endoplasmic reticulum–mitochondria coupling

(2015) Riccardo Filadi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Mitofusin-2–dependent inactivating cleavage of Opa1 links changes in mitochondriacristaeand ER contacts in the postprandial liver

(2014) Aditi Sood et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imaging intraorganellar Ca2+ at subcellular resolution using CEPIA

(2014) Junji Suzuki et al.   Nature Communications

ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43

(2014) Radu Stoica et al.   Nature Communications

MAM (mitochondria-associated membranes) in mammalian cells: Lipids and beyond

(2013) Jean E. Vance   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Mitofusin 2 in POMC Neurons Connects ER Stress with Leptin Resistance and Energy Imbalance

(2013) Marc Schneeberger et al.   CELL

Mfn2 modulates the UPR and mitochondrial function via repression of PERK

(2013) Juan Pablo Muñoz et al.   EMBO JOURNAL

MITOL Regulates Endoplasmic Reticulum-Mitochondria Contacts via Mitofusin2

(2013) Ayumu Sugiura et al.   MOLECULAR CELL

Autophagosomes form at ER–mitochondria contact sites

(2013) Maho Hamasaki et al.   NATURE

Mitofusin 2-Containing Mitochondrial-Reticular Microdomains Direct Rapid Cardiomyocyte Bioenergetic Responses Via Interorganelle Ca 2+ Crosstalk

(2012) Yun Chen et al.   CIRCULATION RESEARCH

Upregulated function of mitochondria-associated ER membranes in Alzheimer disease

(2012) Estela Area-Gomez et al.   EMBO JOURNAL

Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons

(2012) Seungmin Lee et al.   HUMAN MOLECULAR GENETICS

Endoplasmic reticulum–mitochondria contacts: function of the junction

(2012) Ashley A. Rowland et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitofusin-2 Independent Juxtaposition of Endoplasmic Reticulum and Mitochondria: An Ultrastructural Study

(2012) Pierre Cosson et al.   PLoS One

Dimerization-Dependent Green and Yellow Fluorescent Proteins

(2012) Spencer C. Alford et al.   ACS Synthetic Biology

VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis

(2011) Kurt J. De Vos et al.   HUMAN MOLECULAR GENETICS

Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress

(2011) R. Bravo et al.   JOURNAL OF CELL SCIENCE

Mitochondria Supply Membranes for Autophagosome Biogenesis during Starvation

(2010) Dale W. Hailey et al.   CELL

Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction

(2010) Ryota Iwasawa et al.   EMBO JOURNAL

Imaging Interorganelle Contacts and Local Calcium Dynamics at the ER-Mitochondrial Interface

(2010) György Csordás et al.   MOLECULAR CELL

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease

(2009) X. Wang et al.   JOURNAL OF NEUROSCIENCE

Mitofusin-2 regulates mitochondrial and endoplasmic reticulum morphology and tethering: The role of Ras

(2009) Olga Martins de Brito et al.   MITOCHONDRION

Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells

(2009) Mariusz R Wieckowski et al.   Nature Protocols

Mitofusin 2 Builds a Bridge between ER and Mitochondria

(2008) Carsten Merkwirth et al.   CELL

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

(2008) Olga Martins de Brito et al.   NATURE