Article
Agriculture, Dairy & Animal Science
Xuemei Zhao, Jizhe Wang, Ge Gao, Valentino Bontempo, Chiqing Chen, Martine Schroyen, Xilong Li, Xianren Jiang
Summary: Gallic acid supplementation in weaned piglets' diet improves growth performance, especially for low weaning weight piglets, and reduces diarrhea incidence. Additionally, it enhances plasma antioxidant status, leading to better overall health outcomes for the piglets.
Article
Multidisciplinary Sciences
Aytuel Uzun Akgeyik, Emine Yalcin, Kueltigin Cavusoglu
Summary: This study investigated the phytochemical content and biological activities of raw and heat-treated extracts of Ornithogalum umbellatum. The results showed that heat treatment significantly affected the phytochemical content and biological activities of O. umbellatum, leading to a decrease in major compound levels and loss of certain activities.
SCIENTIFIC REPORTS
(2023)
Article
Chemistry, Applied
Ying Li, Lezhen Dong, Yahui Liu, Qin Chen, Zufang Wu, Lingyi Liu, Mohamed A. Farag, Lianliang Liu
Summary: The effects of covalent binding of protocatechuic acid (PA) and gallic acid (GA) to lactoferrin (LF) on the structure, functional, and antioxidant properties of the protein conjugate were investigated. The LF-PA/GA conjugates showed altered hydrodynamic diameter and zeta-potential, but their antioxidant activities remained unchanged.
Article
Environmental Sciences
Anbazhagan Sathiyaseelan, Xin Zhang, Myeong-Hyeon Wang
Summary: This study synthesizes tellurium nanoparticles using an antioxidant molecule and evaluates their biological activity and toxicity. The results show that the nanoparticles have potential antibacterial and anticancer properties, and utilizing biomolecules in their synthesis enhances their biological efficacy and applicability.
ENVIRONMENTAL RESEARCH
(2024)
Article
Chemistry, Applied
Min Zhang, Bin Yang, Zimeng Yuan, Qi Sheng, Changchun Jin, Jun Qi, Manman Yu, Yingnan Liu, Guoyuan Xiong
Summary: This study investigated the effects of adding different concentrations of Gallic acid (GA) (0%, 0.5%, 1.0%, 1.5% w/v) to films fabricated with corn starch and pullulan (CS/PUL) on their mechanical characteristics, hydrophobicity, antioxidant and antibacterial properties, FTIR, SEM and XRD. The addition of 1.0% GA enhanced the mechanical strength and opacity of CS/PUL films. Films with GA exhibited significantly lower water vapor permeability (WVP) than those without. The addition of GA, especially at concentrations of 1.0% and 1.5%, resulted in better free radical scavenging activities on DPPH and improved antibacterial capabilities against E. coli and P. aeruginosa.
Article
Chemistry, Applied
Zhiyun Peng, Yufeng Li, Lijun Tan, Lu Chen, Qiandai Shi, Qiao-Hui Zeng, Haiquan Liu, Jing Jing Wang, Yong Zhao
Summary: A series of gallic acid-benzylidenehydrazine hybrids were synthesized and evaluated for their tyrosinase inhibitory activity. Two compounds, 5d and 5f, showed potent inhibition and also exhibited antioxidant and antibacterial activities, making them potential candidates for novel food preservatives.
Article
Food Science & Technology
Daniel Rodriguez-Rico, Maria de los Angeles Saenz-Esqueda, Jorge Armando Meza-Velazquez, Juan Jose Martinez-Garcia, Jesus Josafath Quezada-Rivera, Monica M. Umana, Rafael Minjares-Fuentes
Summary: This study investigated the bioactive compounds, antioxidant capacity, and microbiological quality of melon juice processed by high-intensity ultrasound (HIUS). The results showed that HIUS processing significantly enhanced the antioxidant capacity of melon juice and reduced microbial load.
Article
Food Science & Technology
Di Wu, Fei Ge, Hong Ma, Ruhui Xia, Weiwei Cheng, Xiaozhi Tang
Summary: In this study, gallic acid was added to common buckwheat Wantuo, and it was found that the addition of gallic acid affected the hydration, pasting properties, and microstructure and texture of the gel. However, there was no significant change in the color of the flours. Structural analysis revealed that the addition of gallic acid decreased the content of rapidly digested starch and increased the content of resistant starch. Additionally, the addition of gallic acid improved the antioxidant activity of the Wantuo and softened its texture.
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2023)
Article
Chemistry, Applied
Hui Wang, Shengping You, Wenhang Wang, Yan Zeng, Rongxin Su, Wei Qi, Kang Wang, Zhimin He
Summary: The study found that laccase can promote the cross-linking of gallic acid and soy protein isolate under neutral pH conditions. Gallic acid significantly enhanced the antioxidant activity of soy protein isolate, increasing DPPH free radical scavenging rate, ABTS free radical scavenging ability, and reducing power.
Article
Biochemistry & Molecular Biology
Wen Zhang, Qing-Min Zeng, Ren-Cheng Tang
Summary: In recent years, the importance of medical textiles for preventing and treating infectious diseases has gained global awareness. This research presents a novel cotton fiber with antibacterial, antioxidant, and drug delivery properties, using the application of biomass molecules. The prepared cotton fiber exhibited durable antibacterial and antioxidant activities, as well as good drug loading and releasing properties for acetylsalicylic acid.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Food Science & Technology
Fakhreddin Salehi, Moein Inanloodoghouz, Sara Ghazvineh
Summary: The aim of this study was to investigate the effects of microwave pretreatments on sweet cherries. The results showed that microwave pretreatment reduced drying time, increased total phenolics content and antioxidant capacity, and enhanced rehydration rate of dried cherries.
FOOD SCIENCE & NUTRITION
(2023)
Article
Polymer Science
Ankita Das, Parvaiz Ahmad Shiekh, Ashok Kumar
Summary: A novel stent design using biomimetically designed trilayered electrospun materials has been developed to avoid restenosis and promote re-endothelialization of damaged blood vessels. The stent material demonstrated excellent antioxidant potential and hemocompatibility, reducing smooth muscle cell growth on the scaffold.
EUROPEAN POLYMER JOURNAL
(2021)
Article
Chemistry, Physical
Samy M. El-Megharbel, Reham Z. Hamza
Summary: Gallic acid metal complexes were prepared and characterized. Gallic acid acted as a bidentate ligand with various metal ions and formed complexes with different geometries and surface morphologies. The complexes exhibited good thermal properties and antioxidant activities.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Chemistry, Physical
Shadi Molaei, Abbas Dadkhah Tehrani, Hamidreza Shamlouei
Summary: The biocompatibility, biodegradability, low-cost, and rich chemistry of carbohydrates make them promising materials for biomedical applications. Recent research has focused on exploring new polymeric antioxidants based on natural and synthetic carbohydrates. In this study, the antioxidant activity of two glucose conjugated derivatives of gallic acid was investigated using density functional theory (DFT) method. The results showed that the BDE mechanism is the best descriptor for evaluating antioxidant activities, and GG was found to be the most reactive antioxidant compound.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Polymer Science
Roberta Cassano, Federica Curcio, Roberta Sole, Sonia Trombino
Summary: Exposure to UV radiation can damage the skin and cause inflammation and aging. The skin has natural antioxidants and enzymes to protect against UV damage, but aging and stress can reduce their levels. Plant foods provide natural antioxidants that can help reduce UV-induced skin damage. This study used gallic acid and phloretin to create polymeric microspheres that effectively released phloretin, providing protection against UV damage.
Article
Biochemistry & Molecular Biology
Andressa Mara Baseggio, Larissa Akemi Kido, Juliane Vigano, Mara Junqueira Carneiro, Celina de Almeida Lamas, Julian Martinez, Alexandra Christine Helena Frankland Sawaya, Valeria Helena Alves Cagnon, Mario Roberto Marostica Junior
Summary: The study evaluated the impact of yellow passion fruit bagasse extract on systemic oxidative and inflammatory parameters in prostate cancer progression, showing promising potential as an adjuvant during the initial steps of the disease.
JOURNAL OF FOOD BIOCHEMISTRY
(2022)
Review
Nutrition & Dietetics
Gabriela de Freitas Laiber Pascoal, Marina Vilar Geraldi, Mario Roberto Marostica, Thomas Prates Ong
Summary: Ingesting antioxidant bioactive food compounds can protect the male reproductive system from damage, improve spermatogenesis, and benefit both fathers and offspring. Paternal nutrition can alter sperm epigenome, affecting fetal development and increasing the risk of metabolic diseases and breast cancer in adulthood.
Article
Oncology
Larissa Akemi Kido, Isabela Maria Urra Rossetto, Andressa Mara Baseggio, Gabriela Bortolanza Chiarotto, Leticia Ferreira Alves, Felipe Rabelo Santos, Celina de Almeida Lamas, Mario Roberto Marostica, Valeria Helena Alves Cagnon
Summary: Jaboticaba is a Brazilian berry rich in fibers and bioactive compounds, which exhibits high antioxidant and antiproliferative activities. This study aimed to investigate the molecular targets and mechanisms of action of Jaboticaba peel extract (JPE) in prostate cancer (PCa) cell lines with different androgenic status. The results showed that JPE reduced cell viability in both LNCaP and PC-3 cell lines, with LNCaP showing greater sensitivity. JPE also modulated gene expression related to apoptosis, inflammation, angiogenesis, and metastasis, suggesting its potential as an antitumor agent for PCa.
JOURNAL OF CANCER PREVENTION
(2022)
Article
Biotechnology & Applied Microbiology
Patricia A. Caetano, Tatiele C. do Nascimento, Andressa S. Fernandes, Pricila P. Nass, Karem R. Vieira, Mario R. Marostica Junior, Eduardo Jacob-Lopes, Leila Q. Zepka
Summary: Polysaccharides are important macromolecules in living organisms, and marine polysaccharides from microalgae have diverse applications in food, cosmetics, and health. Despite challenges in extraction, identification, and purification, microalgae show promise as a potential source for polysaccharide production.
BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY
(2022)
Article
Chemistry, Medicinal
Natalia Crialeison Balbo Vall Ribeiro, Amanda E. Ramer-Tait, Cinthia Bau Betim Cazarin
Summary: Resistant starch is a glucose plant polymer that is widely available in nature and can be easily obtained through simple technological processes. It acts as dietary fiber and is metabolized by gut microbiota to produce beneficial short-chain fatty acids, promoting a range of positive effects on human metabolism. Researchers worldwide have been investigating the inclusion of resistant starch in the diet and its potential to counteract chronic non-communicable diseases.
Article
Biology
Marjorie Barcha Longo, Celina de Almeida Lamas, Isabela Urra Rossetto, Ellen Nogueira-Lima, Carla Beatriz Collares-Busatto, Mario Roberto Marostica Junior, Valeria Helena Alves Cagnon Quitete
Summary: The Brazilian berry, also known as jaboticaba, has been found to have antioxidant and anti-inflammatory properties, as well as positive effects on hormonal regulation and weight loss. This study shows that a low dose of jaboticaba peel extract can limit damages to the anterior prostate and prevent hormone receptor alterations associated with aging or high-fat diet. The extract reduces atrophy and inflammatory infiltrate frequencies, decreases the expression of androgen receptor, estrogen receptor alpha, and insulin-like growth factor 1 receptor, and lowers the incidence of prostatic intraepithelial neoplasia. Overall, jaboticaba extract protects the anterior prostate microenvironment and prevents lesion development.
BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY
(2023)
Article
Neurosciences
Nathalia Medina dos Santos, Angela Giovana Batista, Monique Culturato Padilha Mendonca, Celio Fernando Figueiredo Angolini, Renato Grimaldi, Glaucia Maria Pastore, Cesar Renato Sartori, Maria Alice da Cruz-Hoefling, Mario Roberto Marostica Jr
Summary: This study investigated the effect of Amazonian acai pulp intake in the prevention of memory and cognitive impairment resulting from a high-fat diet. The results showed that the consumption of acai pulp improved peripheral insulin sensitivity and phosphorylation of AKT/GSK3-beta, leading to better cognitive behavior.
NUTRITIONAL NEUROSCIENCE
(2023)
Article
Immunology
Ellen Cristina Souza de Oliveira, Lesvi Moya Dalmau, Celso Acacio Rodrigues de Almeida Costa, Luiz Domingues de Almeida Junior, Cintia Reis Ballard, Mario Roberto Marostica Junior, Marcella Aparecida Stahl, Renato Grimaldi, Aline Witaicenis, Luiz Claudio Di Stasi
Summary: This study evaluated the anti-inflammatory effects of avocado fruit pulp on intestinal inflammation in rats. The results showed that dietary intervention with 20% avocado pulp could reduce the severity of colonic lesions, inhibit the production of inflammatory factors, and did not cause adverse effects on biochemical or behavioral parameters in rats.
INFLAMMOPHARMACOLOGY
(2023)
Article
Food Science & Technology
Luana Dias Campos, Anna Thereza Santiago de Almeida Pereira, Cinthia Bail Betim Cazarin
Summary: This study aimed to evaluate consumers' perceptions, knowledge, attitudes, and practices about the consumption of collagen-based products. The results showed that collagen supplementation is popular among consumers, with an emphasis on aesthetic care. However, the scientific literature has also shown its effects in treating osteoarticular diseases.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Food Science & Technology
Juliana Kelly da Silva-Maia, Arumugam Nagalingam, Cinthia Bail Betim Cazarin, Mario Roberto Marostica Jr, Dipali Sharma
Summary: Jaboticaba peel extracts (JE1 and JE2) were found to exhibit anticancer activity against breast cancer cells. Both JE1 and JE2 showed inhibitory effects on the clonogenic potential, anchorage-independent growth, cell viability, migration, and invasion of breast cancer cells. Mechanistically, JE1 induced apoptosis and increased endoplasmic stress. These findings suggest that Jaboticaba peel extracts have potential for further development as a treatment for breast cancer.
FOOD CHEMISTRY: MOLECULAR SCIENCES
(2023)
Review
Multidisciplinary Sciences
Luana Dias Campos, Valfredo de Almeida Santos Junior, Julia Demuner Pimentel, Gabriel Lusi Fernandes Carrega, Cinthia Bau Betim Cazarin
Summary: Collagen is a major component of the extracellular matrix in the skin and articular cartilage, affecting the body's mechanical and tissue formation properties. Literature review shows that collagen supplementation can improve skin conditions and orthopedic ailments by reducing wrinkles, increasing elasticity and hydration, and enhancing bone strength and joint mobility. This indicates the potential economic and health benefits of collagen derived from food industry by-products.
Article
Agriculture, Dairy & Animal Science
Jhoseline Stayce Guillen Sanchez, Cinthia Bau Betim Cazarin, Miriam Regina Canesin, Felix G. R. Reyes, Amadeu Hoshi Iglesias, Marcelo Cristianini
Summary: The aim of the study was to extract bioactive compounds from purple corn cob using high isostatic pressure at different temperatures. The extract obtained by high pressure extraction showed higher antioxidant activity and bioactive compound content compared to conventional extraction. High isostatic pressure increased the extraction of bioactive compounds by more than 50% and obtained them in shorter times, offering a new alternative and eco-friendly method for extracting bioactive compounds from plant tissues.
SCIENTIA AGROPECUARIA
(2023)
Article
Agriculture, Dairy & Animal Science
Jhoseline Stayce Guillen Sanchez, Cinthia Bau Betim Cazarin, Miriam Regina Canesin, Felix Reyes Reyes, Amadeu Hoshi Iglesias, Marcelo Cristianini
Summary: The study evaluated the effects of dynamic high pressure at different processing temperatures on the extraction of bioactive compounds from Peruvian purple corn cob. The results showed that dynamic high pressure at 60 MPa / 45 degrees C was capable of obtaining extracts with bioactive compound contents and high antioxidant activity corresponding to those obtained using the conventional process. Furthermore, the dynamic high pressure significantly increased the extraction of anthocyanins.
SCIENTIA AGROPECUARIA
(2023)
Article
Physiology
Patricia Berilli, Gustavo Bernardes Fanaro, Jessica Piva Santos, Felix Guillermo Reyes Reyes, Amadeu Hoshi Iglesias, Marcella Reis, Cinthia Baul Betim Cazarin, Mario Roberto Marostica Junior
Summary: This study evaluated the impact of white tea on antioxidant status after strenuous exercise. The results showed that white tea consumption increased serum antioxidant capacity and reduced inflammatory markers. Additionally, white tea intake improved antioxidant defenses and decreased lipid oxidation in liver tissue.
CURRENT RESEARCH IN PHYSIOLOGY
(2022)
Article
Nutrition & Dietetics
Daiane Policena dos Santos, Bruna Cristina Seibert, Giovana Cristina Ceni, Greisse Viero da Silva Leal, Angela Giovana Batista
Summary: This study found that inadequate water consumption is associated with increased hip circumference and body adiposity index. Among overweight and obese individuals, only a small number consumed sufficient water. Therefore, it is important for healthcare professionals, especially dietitians, to assess and intervene in the population's water consumption habits.
RBONE-REVISTA BRASILEIRA DE OBESIDADE NUTRICAO E EMAGRECIMENTO
(2022)
Article
Chemistry, Applied
M. Graca Dias, Elsa Vasco, Francisco Ravasco, Lufsa Oliveira
Summary: This study estimated the vitamin D intake of "adults" and "elderly" populations in Portugal using the TDS methodology. The results showed that the majority of people had inadequate vitamin D intake, well below the Dietary Reference Values.
Article
Chemistry, Applied
Yanan Wang, Jiachen Shi, Yong-Jiang Xu, Chin-Ping Tan, Yuanfa Liu
Summary: This study investigates the variations in lipid digestion profiles among individuals of different ages using in vitro digestion models. The findings suggest that adults have a more comprehensive lipid digestion compared to infants, and infants tend to release shorter chain length and more saturated free fatty acids during digestion. Additionally, the particle sizes in the stomach of the elderly were consistently larger. This study enhances our understanding of how lipids with different degrees of unsaturation undergo digestion in diverse age groups.
Article
Chemistry, Applied
Hyunjong Yu, Huisu Kim, Pahn-Shick Chang
Summary: Chitosan-pectin emulsion-filled hydrogel (EFH) was developed to enhance the bioaccessibility of lipophilic bioactive compounds through intestinal delivery. The EFH, prepared without crosslinking agents, demonstrated improved mechanical strength and compactness with higher pectin concentration. It retained the emulsion at pH 2.0 and released it at pH 7.4, resulting in enhanced release of free fatty acids and improved bioaccessibility of curcumin.
Article
Chemistry, Applied
Tongze Zhang, Siqi Hong, Jia-Rong Zhang, Pin-He Liu, Siyi Li, Zixian Wen, Jianwei Xiao, Guirong Zhang, Olivier Habimana, Nagendra P. Shah, Zhongquan Sui, Harold Corke
Summary: Lactic acid fermentation significantly affects the morphology and physicochemical properties of proso millet starch, including the formation of surface indentations and small pores, decrease in gelatinization temperatures, and changes in hardness and adhesiveness.
Article
Chemistry, Applied
Liqin Kong, Feng Hong, Peng Luan, Yiping Chen, Yaoze Feng, Ming Zhu
Summary: This study presents a novel impedance biosensor using composite nanomaterials and T1R1 as a signal probe, which can competitively and ultra-sensitively detect umami intensity. The biosensor exhibits exceptional analytical performance and is suitable for food flavor evaluation.
Article
Chemistry, Applied
Kunying Lv, Yixin Yang, Qilong Li, Ran Chen, Liang Deng, Yiwei Zhang, Ning Jiang
Summary: Horse's milk, with its high nutritional value and low allergenic proteins, could be a substitute for cow's milk in infant consumption. A proteomic method was used to identify and compare milk fat globule membrane (MFGM) and whey proteins from different horse breeds. The study found differences in protein composition and functionality, which could support the development of formulas more suitable for human infants.
Article
Chemistry, Applied
Enrique Jacobo Diaz-Montana, Helene Brignot, Ramon Aparicio-Ruiz, Thierry Thomas- Danguin, Maria Teresa Morales
Summary: Sensory perception of virgin olive oil is influenced by phenols and volatiles, which are affected by the composition of the oil and biological factors. This study investigated the effect of saliva and phenols on the release of volatiles, and found that the presence of phenols decreased the release of saturated volatiles.
Article
Chemistry, Applied
Wei Zhou, Rui Zhang, Zhen Cai, Fangfang Wu, Yong Hu, Chao Huang, Kun Hu, Yun Chen
Summary: Environmentally friendly and outstanding pH-responsive cationic starch nanoparticles (CSNP) were prepared from pH-sensitive starch. CSNP exhibited nanosize and regular sphere, highly free-flowing molecular chains, and demonstrated excellent pH responsiveness through multiple emulsion/demulsification transitions.
Article
Chemistry, Applied
Andrea Koo, Vinayak Ghate, Weibiao Zhou
Summary: This study suggests that direct seeding may negatively affect the nutritional quality of crops, causing a decrease in ascorbic acid, vitamin K, and total glucosinolate content.
Article
Chemistry, Applied
Tonghao Du, Yazhou Xu, Xiaoyan Xu, Shijin Xiong, Linli Zhang, Biao Dong, Jinqing Huang, Tao Huang, Muyan Xiao, Tao Xiong, Mingyong Xie
Summary: This study successfully improved the ACE inhibitory activity of black sesame seeds by fermenting them with Lactobacillus Plantarum NCU116 and hydrolyzing them using acid protease. The RF-PSO model was used to predict the ACE inhibitory activity during the hydrolysis process. Eight peptides with ACE inhibitory activity were identified from fermented black sesame seed hydrolysates after separation and screening.
Article
Chemistry, Applied
Yao Liu, Songyi Lin, Kexin Liu, Shan Wang, Qiaozhen Liu, Na Sun
Summary: This study analyzed the structural changes of shrimp proteins during digestion, predicted the immunodominant epitopes, and validated their allergenicity. The results showed that shrimp proteins were degraded into peptides during digestion, but still carried IgE epitopes that trigger allergic reactions.
Article
Chemistry, Applied
Tiantian Fu, Hongwei Cao, Yu Zhang, Xiao Guan
Summary: This study investigates the impact of milling on the active components in rice, with a focus on the stability and bioaccessibility of phenols, VB1, and alpha-GABA during cooking and digestion. The findings show that milling exacerbates the instability of gamma-GABA during cooking and VB1 during digestion, and it affects the bioaccessibility of these active compounds.
Article
Chemistry, Applied
Zhihao Yang, Yanru Hou, Min Zhang, Puxin Hou, Chang Liu, Lu Dou, Xiaoyu Chen, Lihua Zhao, Lin Su, Ye Jin
Summary: This study investigated the molecular mechanism of feeding regimes on lamb flavor by using TMT labeling combined with MS. The results showed that pasture-fed groups had higher levels of amino acids and volatile flavor substances compared to concentrate-fed groups. Additionally, several differentially abundant proteins associated with lamb flavor were identified.
Article
Chemistry, Applied
Zixuan Xie, De Zhang, Junyu Zhu, Qianqian Luo, Jun Liu, Jingtao Zhou, Xiaoyong Wang, Yuqiong Chen, Zhi Yu, Dejiang Ni
Summary: This study investigated the acidification of aroma-enhanced black tea during storage. Analysis of non-volatile substances and organic acids using UPLC-Q-TOF/MS and HPLC revealed a decrease in soluble sugars and amino acids, while an increase in organic acids such as oxalic acid, malic acid, and quinic acid. In vitro experiments further demonstrated that the acidification is a result of the decomposition of sugars and amino acids by heating, as well as the oxidation of aromatic aldehydes. Additionally, the study showed that the taste composition of tea infusion is altered, with reduced amino acids, catechins, soluble sugars, and flavonoids. This research provides a theoretical basis for improving the quality of black tea.
Article
Chemistry, Applied
Lin Wang, Falai Ma, Zihan Li, Yan Zhang
Summary: This study developed time-temperature integrators based on amyloglucosidase@Cu3(PO4)2 nanoflowers for monitoring the freshness of chilled pork. The results showed that the integrators were highly reliable and accurate in predicting the quality of chilled pork.
