Prophylactic and therapeutic potential of selected immunomodulatory agents from Ayurveda against coronaviruses amidst the current formidable scenario: an in silico analysis

Withanone from Withania somnifera Attenuates SARS-CoV-2 RBD and Host ACE2 Interactions to Rescue Spike Protein Induced Pathologies in Humanized Zebrafish Model

(2021) Acharya Balkrishna et al.   Drug Design Development and Therapy

Identification of novel compounds against three targets of SARS CoV-2 coronavirus by combined virtual screening and supervised machine learning

(2021) Onat Kadioglu et al.   COMPUTERS IN BIOLOGY AND MEDICINE

Ayurveda botanicals in COVID-19 management: An in silico multi-target approach

(2021) Swapnil Borse et al.   PLoS One

Unique epidemiological and clinical features of the emerging 2019 novel coronavirus pneumonia (COVID‐19) implicate special control measures

(2020) Yixuan Wang et al.   JOURNAL OF MEDICAL VIROLOGY

Emerging coronaviruses: Genome structure, replication, and pathogenesis

(2020) Yu Chen et al.   JOURNAL OF MEDICAL VIROLOGY

Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study

(2020) Nanshan Chen et al.   LANCET

Preliminary Identification of Potential Vaccine Targets for the COVID-19 Coronavirus (SARS-CoV-2) Based on SARS-CoV Immunological Studies

(2020) Syed Faraz Ahmed et al.   Viruses-Basel

Of chloroquine and COVID-19

(2020) Franck Touret et al.   ANTIVIRAL RESEARCH

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine

(2020) Wanbo Tai et al.   Cellular & Molecular Immunology

New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19?

(2020) Christian A. Devaux et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

The SARS-CoV-2 outbreak: What we know

(2020) Di Wu et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

COVID-19: a recommendation to examine the effect of hydroxychloroquine in preventing infection and progression

(2020) Dan Zhou et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Putative Inhibitors of SARS-CoV-2 Main Protease from A Library of Marine Natural Products: A Virtual Screening and Molecular Modeling Study

(2020) Davide Gentile et al.   Marine Drugs

Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors

(2020) Linlin Zhang et al.   SCIENCE

The First 75 Days of Novel Coronavirus (SARS-CoV-2) Outbreak: Recent Advances, Prevention, and Treatment

(2020) Yuxin Yan et al.   International Journal of Environmental Research and Public Health

TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes

(2020) Ruochen Zang et al.   Science Immunology

Investigation into SARS-CoV-2 Resistance of Compounds in Garlic Essential Oil

(2020) Bui Thi Phuong Thuy et al.   ACS Omega

Discovering small-molecule therapeutics against SARS-CoV-2

(2020) Vaibhav Tiwari et al.   DRUG DISCOVERY TODAY

In silico identification of potential inhibitors from Cinnamon against main protease and spike glycoprotein of SARS CoV-2

(2020) D. S. N. B. K. Prasanth et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as coronavirus disease 2019 (COVID-19) pandemic: A global health emergency

(2020) Thamina Acter et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Gaining insights on immune responses to the novel coronavirus, COVID-19 and therapeutic challenges

(2020) Mahsa Hajivalili et al.   LIFE SCIENCES

Protease Inhibitory Effect of Natural Polyphenolic Compounds on SARS-CoV-2: An In Silico Study

(2020) Rajveer Singh et al.   MOLECULES

Drug repurposing approach to fight COVID-19

(2020) Thakur Uttam Singh et al.   Pharmacological Reports

Potential bioactive glycosylated flavonoids as SARS-CoV-2 main protease inhibitors: A molecular docking and simulation studies

(2020) Sabri Ahmed Cherrak et al.   PLoS One

Alkaloids from Cryptolepis sanguinolenta as Potential Inhibitors of SARS-CoV-2 Viral Proteins: An In Silico Study

(2020) Lawrence Sheringham Borquaye et al.   Biomed Research International

Multitarget in silico studies of Ocimum menthiifolium, family Lamiaceae against SARS-CoV-2 supported by molecular dynamics simulation

(2020) Amgad Albohy et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Evaluation of traditional ayurvedic Kadha for prevention and management of the novel Coronavirus (SARS-CoV-2) using in silico approach

(2020) Dharmendra Kumar Maurya et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

In silico studies evidenced the role of structurally diverse plant secondary metabolites in reducing SARS-CoV-2 pathogenesis

(2020) Hariprasad Puttaswamy et al.   Scientific Reports

Combating COVID-19: The role of drug repurposing and medicinal plants

(2020) Shah A. Khan et al.   Journal of Infection and Public Health

Steroidal glycoalkaloids from Solanum nigrum target cytoskeletal proteins: an in silico analysis

(2019) Rumana Ahmad   PeerJ

Chyawanprash: A Traditional Indian Bioactive Health Supplement

(2019) Sharma et al.   Biomolecules

Anticancer Potential of Dietary Natural Products: A Comprehensive Review

(2019) Rumana Ahmad et al.   Anti-Cancer Agents in Medicinal Chemistry

LARMD: integration of bioinformatic resources to profile ligand-driven protein dynamics with a case on the activation of estrogen receptor

(2019) Jing-Fang Yang et al.   BRIEFINGS IN BIOINFORMATICS

Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System?

(2019) Marc Desforges et al.   Viruses-Basel

Epigallocatechin-3-gallate inhibits the early stages of Japanese encephalitis virus infection

(2018) Ching-Ying Wang et al.   VIRUS RESEARCH

Identification of Ellagic Acid from Plant Rhodiola rosea L. as an Anti-Ebola Virus Entry Inhibitor

(2018) Qinghua Cui et al.   Viruses-Basel

Antiviral Mechanism of Action of Epigallocatechin-3-O-gallate and Its Fatty Acid Esters

(2018) Kunihiro Kaihatsu et al.   MOLECULES

Effect of alkaline pH on cytotoxicity profile of neem (Azadirachta indica) ethanolic extract against human breast cancer cell line MDA-MB-231

(2018) Anchal Trivedi et al.   European Journal of Integrative Medicine

Tracking virus outbreaks in the twenty-first century

(2018) Nathan D. Grubaugh et al.   Nature Microbiology

SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules

(2017) Antoine Daina et al.   Scientific Reports

Structural insights into conformational stability of both wild-type and mutant EZH2 receptor

(2016) Imlimaong Aier et al.   Scientific Reports

Avian influenza viruses in mammals

(2016) L.A. REPERANT et al.   REVUE SCIENTIFIQUE ET TECHNIQUE-OFFICE INTERNATIONAL DES EPIZOOTIES

The SARS-coronavirus papain-like protease: Structure, function and inhibition by designed antiviral compounds

(2015) Yahira M. Báez-Santos et al.   ANTIVIRAL RESEARCH

Antiviral activity and possible mode of action of ellagic acid identified in Lagerstroemia speciosa leaves toward human rhinoviruses

(2014) Sang Wook Park et al.   BMC Complementary and Alternative Medicine

Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4

(2013) Nianshuang Wang et al.   CELL RESEARCH

In Silico ADMET Prediction: Recent Advances, Current Challenges and Future Trends

(2013) Feixiong Cheng et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Indian Traditional Ayurvedic System of Medicine and Nutritional Supplementation

(2013) M. M. Pandey et al.   Evidence-based Complementary and Alternative Medicine

Anti-infective properties of epigallocatechin-3-gallate (EGCG), a component of green tea

(2012) J Steinmann et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mechanisms of Coronavirus Cell Entry Mediated by the Viral Spike Protein

(2012) Sandrine Belouzard et al.   Viruses-Basel

Understanding drug-likeness

(2011) Oleg Ursu et al.   Wiley Interdisciplinary Reviews-Computational Molecular Science

The graphical representation of ADME-related molecule properties for medicinal chemists

(2010) Timothy J. Ritchie et al.   DRUG DISCOVERY TODAY

Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

(2009) Frank Lovering et al.   JOURNAL OF MEDICINAL CHEMISTRY