Steroidal glycoalkaloids from Solanum nigrum target cytoskeletal proteins: an in silico analysis

ATP competes with PIP2 for binding to gelsolin

(2018) Dávid Szatmári et al.   PLoS One

Elucidation of GlcNAc-binding properties of type III intermediate filament proteins, using GlcNAc-bearing polymers

(2017) Hirohiko Ise et al.   GENES TO CELLS

Structural characterization suggests models for monomeric and dimeric forms of full-length ezrin

(2016) J. M. Phang et al.   BIOCHEMICAL JOURNAL

Structural Basis for Noncanonical Substrate Recognition of Cofilin/ADF Proteins by LIM Kinases

(2016) Stephanie Hamill et al.   MOLECULAR CELL

Chemical Structure-Related Drug-Like Criteria of Global Approved Drugs

(2016) Fei Mao et al.   MOLECULES

Synthesis, molecular properties, toxicity and biological evaluation of some new substituted imidazolidine derivatives in search of potent anti-inflammatory agents

(2016) Asif Husain et al.   SAUDI PHARMACEUTICAL JOURNAL

Evaluation of uttroside B, a saponin from Solanum nigrum Linn, as a promising chemotherapeutic agent against hepatocellular carcinoma

(2016) Lekshmi R. Nath et al.   Scientific Reports

A Review of Bioinsecticidal Activity of Solanaceae Alkaloids

(2016) Szymon Chowański et al.   Toxins

Chemistry and Anticarcinogenic Mechanisms of Glycoalkaloids Produced by Eggplants, Potatoes, and Tomatoes

(2015) Mendel Friedman   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Intermediate Filaments Play a Pivotal Role in Regulating Cell Architecture and Function

(2015) Jason Lowery et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plasmodium falciparum coronin organizes arrays of parallel actin filaments potentially guiding directional motility in invasive malaria parasites

(2015) Maya A Olshina et al.   MALARIA JOURNAL

Prediction of the Biological Activity Spectra of Organic Compounds Using the Pass Online Web Resource

(2014) D. A. Filimonov et al.   Chemistry of Heterocyclic Compounds

Antiproliferative effect of Solanum nigrum on human leukemic cell lines

(2014) Reema Gabrani et al.   INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES

Post-translational modifications of intermediate filament proteins: mechanisms and functions

(2014) Natasha T. Snider et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural basis of thymosin- 4/profilin exchange leading to actin filament polymerization

(2014) B. Xue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design, Synthesis, andIn VitroAntioxidant Activity of 1,3,5-Trisubstituted-2-pyrazolines Derivatives

(2013) P. C. Jagadish et al.   Journal of Chemistry

Pivotal role of the RanBP9-cofilin pathway in Aβ-induced apoptosis and neurodegeneration

(2012) J A Woo et al.   CELL DEATH AND DIFFERENTIATION

Dynamic behaviors of vimentin induced by interaction with GlcNAc molecules

(2012) Kenta Komura et al.   GLYCOBIOLOGY

The Chloroform Fraction of Solanum nigrum Suppresses Nitric Oxide and Tumor Necrosis Factor-α in LPS-Stimulated Mouse Peritoneal Macrophages Through Inhibition of p38, JNK and ERK1/2

(2011) Hee Kang et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Activation of F-Actin Binding Capacity of Ezrin: Synergism of PIP2 Interaction and Phosphorylation

(2011) Sabine Bosk et al.   BIOPHYSICAL JOURNAL

Selective cell cycle arrest and induction of apoptosis in human prostate cancer cells by a polyphenol-rich extract of Solanum nigrum

(2011) Sanjay Gupta   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Bioactivities of Glycoalkaloids and Their Aglycones from Solanum Species

(2011) Sinead Eileen Milner et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Actin filament severing by cofilin is more important for assembly than constriction of the cytokinetic contractile ring

(2011) Qian Chen et al.   JOURNAL OF CELL BIOLOGY

In-vitro antiviral activity of Solanum nigrum against Hepatitis C Virus

(2011) Tariq Javed et al.   Virology Journal

Synthesis and evaluation of in vitro anticancer activity of novel solasodine derivatives

(2010) Xiao Ming Zha et al.   CHINESE CHEMICAL LETTERS

Vimentin induces changes in cell shape, motility, and adhesion during the epithelial to mesenchymal transition

(2010) Melissa G. Mendez et al.   FASEB JOURNAL

Chemical Composition of Solanum nigrum Linn Extract and Induction of Autophagy by Leaf Water Extract and Its Major Flavonoids in AU565 Breast Cancer Cells

(2010) Hsiu-Chen Huang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Withaferin A Targets Intermediate Filaments Glial Fibrillary Acidic Protein and Vimentin in a Model of Retinal Gliosis

(2010) Paola Bargagna-Mohan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Saponins as cytotoxic agents: a review

(2010) Irma Podolak et al.   PHYTOCHEMISTRY REVIEWS

Apoptosis inducing activity of steroidal constituents from Solanum xanthocarpum and Asparagus racemosus

(2010) K.K. Bhutani et al.   PHYTOMEDICINE

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Proteome of Acidic Phospholipid-binding Proteins

(2009) Kazuya Tsujita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

(2009) Oleg Trott et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Antitumor and immunomodulating effects of polysaccharides isolated fromSolanum nigrumLinne

(2009) Jian Li et al.   PHYTOTHERAPY RESEARCH

Ca2+ binding by domain 2 plays a critical role in the activation and stabilization of gelsolin

(2009) S. Nag et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A role for actin in regulating apoptosis/programmed cell death: evidence spanning yeast, plants and animals

(2008) Vernonica E. Franklin-Tong et al.   BIOCHEMICAL JOURNAL

Providing cellular signposts - Post-translational modifications of intermediate filaments

(2008) Claire L. Hyder et al.   FEBS LETTERS

Aqueous extract of Solanum nigrum inhibit growth of cervical carcinoma (U14) via modulating immune response of tumor bearing mice and inducing apoptosis of tumor cells

(2008) Jian Li et al.   FITOTERAPIA

Inhibitory effect of Solanum nigrum on thioacetamide-induced liver fibrosis in mice

(2008) Chang-Chi Hsieh et al.   JOURNAL OF ETHNOPHARMACOLOGY

Hepatoprotective effects of Solanum nigrum Linn extract against CCl4-iduced oxidative damage in rats

(2007) Hui-Mei Lin et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Induction of apoptosis in HepG2 cells by solanine and Bcl-2 protein

(2007) Y.B. Ji et al.   JOURNAL OF ETHNOPHARMACOLOGY