Interchangeability of periplasmic adaptor proteins AcrA and AcrE in forming functional efflux pumps with AcrD in Salmonella enterica serovar Typhimurium

RND efflux pumps in Gram-negative bacteria; regulation, structure and role in antibiotic resistance

(2020) Abigail L Colclough et al.   Future Microbiology

Cryo-EM Structure and Molecular Dynamics Analysis of the Fluoroquinolone Resistant Mutant of the AcrB Transporter from Salmonella

(2020) Rachel M. Johnson et al.   Microorganisms

Identification of binding residues between periplasmic adapter protein (PAP) and RND efflux pumps explains PAP-pump promiscuity and roles in antimicrobial resistance

(2019) Helen E. McNeil et al.   PLoS Pathogens

Role of bacterial efflux pumps in biofilm formation

(2018) Ilyas Alav et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Upregulation of AcrEF in Quinolone Resistance Development in Escherichia coli When AcrAB-TolC Function Is Impaired

(2018) Chuan-Zhen Zhang et al.   Microbial Drug Resistance

Multidrug efflux pumps: structure, function and regulation

(2018) Dijun Du et al.   NATURE REVIEWS MICROBIOLOGY

An allosteric transport mechanism for the AcrAB-TolC multidrug efflux pump

(2017) Zhao Wang et al.   eLife

Molecular Rationale behind the Differential Substrate Specificity of Bacterial RND Multi-Drug Transporters

(2017) Venkata Krishnan Ramaswamy et al.   Scientific Reports

The Challenge of Efflux-Mediated Antibiotic Resistance in Gram-Negative Bacteria

(2015) Xian-Zhi Li et al.   CLINICAL MICROBIOLOGY REVIEWS

Architecture and roles of periplasmic adaptor proteins in tripartite efflux assemblies

(2015) Martyn F. Symmons et al.   Frontiers in Microbiology

Characterization of AcrD, a Resistance-Nodulation-Cell Division-type multidrug efflux pump from the fire blight pathogen Erwinia amylovora

(2014) Daniel Pletzer et al.   BMC MICROBIOLOGY

Expression of homologous RND efflux pump genes is dependent upon AcrB expression: implications for efflux and virulence inhibitor design

(2014) Jessica M. A. Blair et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

β-Lactam Selectivity of Multidrug Transporters AcrB and AcrD Resides in the Proximal Binding Pocket

(2014) Naoki Kobayashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the AcrAB–TolC multidrug efflux pump

(2014) Dijun Du et al.   NATURE

Molecular mechanisms of antibiotic resistance

(2014) Jessica M. A. Blair et al.   NATURE REVIEWS MICROBIOLOGY

Redundancy in the periplasmic adaptor proteins AcrA and AcrE provides resilience and an ability to export substrates of multidrug efflux

(2013) Helen E. Smith et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

AcrA dependency of the AcrD efflux pump in Salmonella enterica serovar Typhimurium

(2011) Seiji Yamasaki et al.   JOURNAL OF ANTIBIOTICS

Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket

(2011) Ryosuke Nakashima et al.   NATURE

Enhancing the protein production levels in Escherichia coli with a strong promoter

(2010) Hanna Tegel et al.   FEBS Journal

H-NS Modulates Multidrug Resistance of Salmonella enterica Serovar Typhimurium by Repressing Multidrug Efflux Genes acrEF

(2009) K. Nishino et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mechanisms of RND multidrug efflux pumps

(2008) Hiroshi Nikaido et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS