Apple Polyphenol Extract Improves High-Fat Diet-Induced Hepatic Steatosis by Regulating Bile Acid Synthesis and Gut Microbiota in C57BL/6 Male Mice

Distinctive gut microbial dysbiosis between chronic alcoholic fatty liver disease and metabolic‑associated fatty liver disease in mice

(2021) Kai Kang et al.   Experimental and Therapeutic Medicine

Three-station interferometry and tomography: coda versus direct waves

(2020) Shane Zhang et al.   GEOPHYSICAL JOURNAL INTERNATIONAL

Intestinal permeability in human nonalcoholic fatty liver disease: A systematic review and meta‐analysis

(2020) Toon J. I. De Munck et al.   LIVER INTERNATIONAL

Apple polyphenol extract alleviates lipid accumulation in free‐fatty‐acid‐exposed HepG2 cells via activating autophagy mediated by SIRT1 / AMPK signaling

(2020) Deming Li et al.   PHYTOTHERAPY RESEARCH

Bile Acids and FXR: Novel Targets for Liver Diseases

(2020) Mary Stofan et al.   Frontiers in Medicine

Alterations of Bile Acids and Gut Microbiota in Obesity Induced by High Fat Diet in Rat Model

(2019) Hong Lin et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Comprehensive Analysis of Serum and Fecal Bile Acid Profiles and Interaction with Gut Microbiota in Primary Biliary Cholangitis

(2019) Weihua Chen et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

The protective effect and mechanism of the FXR agonist obeticholic acid via targeting gut microbiota in non-alcoholic fatty liver disease

(2019) Dan-Ying Zhang et al.   Drug Design Development and Therapy

Gut Microbiota and Risk of Persistent Nonalcoholic Fatty Liver Diseases

(2019) Han-Na Kim et al.   Journal of Clinical Medicine

Anthocyanins protect the gastrointestinal tract from high fat diet-induced alterations in redox signaling, barrier integrity and dysbiosis

(2019) Eleonora Cremonini et al.   Redox Biology

Apple Polyphenol Extract Alleviates High-Fat-Diet-Induced Hepatic Steatosis in Male C57BL/6 Mice by Targeting LKB1/AMPK Pathway

(2019) Deming Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Why Bile Acids Are So Important in Non-Alcoholic Fatty Liver Disease (NAFLD) Progression

(2019) Aline Gottlieb et al.   Cells

Two apples a day lower serum cholesterol and improve cardiometabolic biomarkers in mildly hypercholesterolemic adults: a randomized, controlled, crossover trial

(2019) Athanasios Koutsos et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Nonalcoholic Fatty Liver Disease: A Challenge from Mechanisms to Therapy

(2019) Giovanni Tarantino et al.   Journal of Clinical Medicine

Obesity treatment by epigallocatechin-3-gallate–regulated bile acid signaling and its enriched Akkermansia muciniphila

(2018) Lili Sheng et al.   FASEB JOURNAL

A next-generation beneficial microbe: Akkermansia muciniphila

(2018) Yuji Naito et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

The gut–liver axis and the intersection with the microbiome

(2018) Anupriya Tripathi et al.   Nature Reviews Gastroenterology & Hepatology

Reversal of metabolic disorders by pharmacological activation of bile acid receptors TGR5 and FXR

(2018) Kavita Jadhav et al.   Molecular Metabolism

Angiopoietin-Like Protein 8 Is a Novel Vitamin D Receptor Target Gene Involved in Non-Alcoholic Fatty Liver Pathogenesis

(2018) Carmelo García-Monzón et al.   AMERICAN JOURNAL OF PATHOLOGY

Ganoderma Lucidum Polysaccharide Peptide Alleviates Hepatoteatosis via Modulating Bile Acid Metabolism Dependent on FXR-SHP/FGF

(2018) Dandan Zhong et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Treatment with camu camu (Myrciaria dubia) prevents obesity by altering the gut microbiota and increasing energy expenditure in diet-induced obese mice

(2018) Fernando F Anhê et al.   GUT

The role of the microbiome in NAFLD and NASH

(2018) Aleksandra A Kolodziejczyk et al.   EMBO Molecular Medicine

Gut microbiota and intestinal FXR mediate the clinical benefits of metformin

(2018) Lulu Sun et al.   NATURE MEDICINE

Bile Acid Control of Metabolism and Inflammation in Obesity, Type 2 Diabetes, Dyslipidemia, and Nonalcoholic Fatty Liver Disease

(2017) Oscar Chávez-Talavera et al.   GASTROENTEROLOGY

Increased Secondary/Primary Bile Acid Ratio in Chronic Heart Failure

(2017) Cristiane C.K. Mayerhofer et al.   JOURNAL OF CARDIAC FAILURE

Amelioration of non-alcoholic fatty liver disease with NPC1L1-targeted IgY or n-3 polyunsaturated fatty acids in mice

(2017) Jin-Sik Bae et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The role of bile acids in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

(2017) Monica D. Chow et al.   MOLECULAR ASPECTS OF MEDICINE

Effect of apple polyphenols on vascular oxidative stress and endothelium function: a translational study

(2017) Arrigo F.G. Cicero et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Effects of Consuming Xylitol on Gut Microbiota and Lipid Metabolism in Mice

(2017) et al.   Nutrients

BAR502, a dual FXR and GPBAR1 agonist, promotes browning of white adipose tissue and reverses liver steatosis and fibrosis

(2017) Adriana Carino et al.   Scientific Reports

On the Dependency of Cellular Protein Levels on mRNA Abundance

(2016) Yansheng Liu et al.   CELL

Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism

(2016) Annika Wahlström et al.   Cell Metabolism

Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol

(2016) Khalidur Rahman et al.   GASTROENTEROLOGY

The globalization of nonalcoholic fatty liver disease: Prevalence and impact on world health

(2016) Mary Rinella et al.   HEPATOLOGY

Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes

(2016) Zobair M. Younossi et al.   HEPATOLOGY

Cyp2c70 is responsible for the species difference in bile acid metabolism between mice and humans

(2016) Shogo Takahashi et al.   JOURNAL OF LIPID RESEARCH

Animal models of non-alcoholic fatty liver disease: current perspectives and recent advances

(2016) Jennie Ka Ching Lau et al.   JOURNAL OF PATHOLOGY

The chemistry of gut microbial metabolism of polyphenols

(2016) Jan F. Stevens et al.   PHYTOCHEMISTRY REVIEWS

Inhibition of ileal bile acid uptake protects against nonalcoholic fatty liver disease in high-fat diet–fed mice

(2016) Anuradha Rao et al.   Science Translational Medicine

Bile Acids and Dysbiosis in Non-Alcoholic Fatty Liver Disease

(2016) Marialena Mouzaki et al.   PLoS One

Nonalcoholic Fatty Liver Disease

(2015) Mary E. Rinella   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

New Insights In Intestinal Sar1B GTPase Regulation and Role in Cholesterol Homeostasis

(2015) Alain Sané et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Hematopoietic overexpression of Cyp27a1 reduces hepatic inflammation independently of 27-hydroxycholesterol levels in Ldlr−/− mice

(2015) Tim Hendrikx et al.   JOURNAL OF HEPATOLOGY

Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease

(2015) Michal Pawlak et al.   JOURNAL OF HEPATOLOGY

A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increasedAkkermansiaspp. population in the gut microbiota of mice

(2014) Fernando F Anhê et al.   GUT

Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease

(2014) Changtao Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Apple Polyphenol Extracts Protect Against Aspirin-induced Gastric Mucosal Damage in Rats

(2014) Gunaranjan Paturi et al.   PHYTOTHERAPY RESEARCH

Fatty Liver Accompanies an Increase in Lactobacillus Species in the Hind Gut of C57BL/6 Mice Fed a High-Fat Diet

(2013) Huawei Zeng et al.   JOURNAL OF NUTRITION

Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity

(2013) Fei Li et al.   Nature Communications

Feasibility and application of liquid–liquid extraction combined with gas chromatography–mass spectrometry for the analysis of phenolic acids from grape polyphenols degraded by human faecal microbiota

(2012) C. Muñoz-González et al.   FOOD CHEMISTRY

Inhibition of apical sodium-dependent bile acid transporter as a novel treatment for diabetes

(2011) Lihong Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Apple Polyphenols Extend the Mean Lifespan of Drosophila melanogaster

(2011) Cheng Peng et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The ABC transporters in lipid flux and atherosclerosis

(2011) Iryna Voloshyna et al.   PROGRESS IN LIPID RESEARCH

Expression of bone morphogenetic protein-2 and its receptors in epithelial ovarian cancer and their influence on the prognosis of ovarian cancer patients

(2010) Ying Ma et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Procyanidin Dimers Are Metabolized by Human Microbiota with 2-(3,4-Dihydroxyphenyl)acetic Acid and 5-(3,4-Dihydroxyphenyl)-γ-valerolactone as the Major Metabolites

(2009) Maaike M. Appeldoorn et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The ecology, epidemiology and virulence of Enterococcus

(2009) K. Fisher et al.   MICROBIOLOGY-SGM