Antigen-specific tolerance approach for rheumatoid arthritis: Past, present and future

Building sophisticated sensors of extracellular cues that enable mammalian cells to work as “doctors” in the body

(2020) Ryosuke Kojima et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Exploiting CD22 To Selectively Tolerize Autoantibody Producing B-Cells in Rheumatoid Arthritis

(2019) Kyle J. Bednar et al.   ACS Chemical Biology

Porphyromonas gingivalis and rheumatoid arthritis

(2019) Carlo Perricone et al.   CURRENT OPINION IN RHEUMATOLOGY

Matured Tolerogenic Dendritic Cells Effectively Inhibit Autoantigen Specific CD4+ T Cells in a Murine Arthritis Model

(2019) Manon A. A. Jansen et al.   Frontiers in Immunology

Origins of rheumatoid arthritis

(2019) Marie-Christophe Boissier et al.   JOINT BONE SPINE

Rheumatoid arthritis and citrullination

(2018) Erika Darrah et al.   CURRENT OPINION IN RHEUMATOLOGY

Immunopathogenesis of Rheumatoid Arthritis

(2017) Gary S. Firestein et al.   IMMUNITY

Novel treatment strategies in rheumatoid arthritis

(2017) Gerd R Burmester et al.   LANCET

Autologous tolerogenic dendritic cells for rheumatoid and inflammatory arthritis

(2016) G M Bell et al.   ANNALS OF THE RHEUMATIC DISEASES

Reengineering chimeric antigen receptor T cells for targeted therapy of autoimmune disease

(2016) C. T. Ellebrecht et al.   SCIENCE

Gene Therapy Induces Antigen-Specific Tolerance in Experimental Collagen-Induced Arthritis

(2016) Sara Tengvall et al.   PLoS One

Identification and characterisation of citrullinated antigen-specific B cells in peripheral blood of patients with rheumatoid arthritis

(2015) Priscilla F Kerkman et al.   ANNALS OF THE RHEUMATIC DISEASES

Immune Tolerance Induction with Multiepitope Peptide Derived from Citrullinated Autoantigens Attenuates Arthritis Manifestations in Adjuvant Arthritis Rats

(2015) Smadar Gertel et al.   JOURNAL OF IMMUNOLOGY

DEC205+Dendritic Cell–Targeted Tolerogenic Vaccination Promotes Immune Tolerance in Experimental Autoimmune Arthritis

(2015) Rachel Spiering et al.   JOURNAL OF IMMUNOLOGY

Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients

(2015) Helen Benham et al.   Science Translational Medicine

Antigen-Specific Tolerogenic Dendritic Cells Ameliorate the Severity of Murine Collagen-Induced Arthritis

(2015) Bin Ning et al.   PLoS One

Anticyclic Citrullinated Peptide Antibodies in Rheumatoid and Nonrheumatoid Rheumatic Disorders: Experience with 1162 Patients

(2014) J. Payet et al.   JOURNAL OF RHEUMATOLOGY

Type 1 regulatory T cells specific for collagen type II as an efficient cell-based therapy in arthritis

(2014) Hélène Asnagli et al.   ARTHRITIS RESEARCH & THERAPY

Antigen-Specific Gene Therapy after Immunisation Reduces the Severity of Collagen-Induced Arthritis

(2013) Tove Eneljung et al.   Clinical & Developmental Immunology

Enhanced antitumor immunotherapeutic effect of B-cell-based vaccine transduced with modified adenoviral vector containing type 35 fiber structures

(2013) E-K Kim et al.   GENE THERAPY

Amelioration of arthritis through mobilization of peptide-specific CD8+ regulatory T cells

(2013) Jianmei W. Leavenworth et al.   JOURNAL OF CLINICAL INVESTIGATION

Tolerogenic dendritic cell therapy for rheumatoid arthritis: where are we now?

(2012) C. M. U. Hilkens et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery

(2012) Moa Fransson et al.   Journal of Neuroinflammation

Disease-Dependent Local IL-10 Production Ameliorates Collagen Induced Arthritis in Mice

(2012) Louise Henningsson et al.   PLoS One

2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative

(2010) Daniel Aletaha et al.   ARTHRITIS AND RHEUMATISM

CEL-2000: A therapeutic vaccine for rheumatoid arthritis arrests disease development and alters serum cytokine/chemokine patterns in the bovine collagen type II induced arthritis in the DBA mouse model

(2010) Daniel H. Zimmerman et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Modulation of collagen-induced arthritis by adenovirus-mediated intra-articular expression of modified collagen type II

(2010) Bo Tang et al.   ARTHRITIS RESEARCH & THERAPY

Antibodies to several citrullinated antigens are enriched in the joints of rheumatoid arthritis patients

(2009) Omri Snir et al.   ARTHRITIS AND RHEUMATISM

Antibodies to citrullinated proteins: molecular interactions and arthritogenicity

(2009) Hüseyin Uysal et al.   IMMUNOLOGICAL REVIEWS

Antigen-Specific Suppression of Inflammatory Arthritis Using Liposomes

(2009) C. Capini et al.   JOURNAL OF IMMUNOLOGY

Tolerance Induction Using Lentiviral Gene Delivery Delays Onset and Severity of Collagen II Arthritis

(2009) Inger Gjertsson et al.   MOLECULAR THERAPY

A multicenter, double-blind, randomized, controlled phase III clinical trial of chicken type II collagen in rheumatoid arthritis

(2009) Wei Wei et al.   ARTHRITIS RESEARCH & THERAPY

Growth inhibition of an established A431 xenograft tumor by a full-length anti-EGFR antibody following gene delivery by AAV

(2008) D T Ho et al.   CANCER GENE THERAPY

Regulatory T cells (Treg) in rheumatoid arthritis

(2008) Marie-Christophe Boissier et al.   JOINT BONE SPINE

A novel recombinant peptide containing only two T–cell tolerance epitopes of chicken type II collagen that suppresses collagen-induced arthritis

(2008) Caixia Xi et al.   MOLECULAR IMMUNOLOGY

Construction and characterization of a novel DNA vaccine that is potent antigen-specific tolerizing therapy for experimental arthritis by increasing CD4+CD25+Treg cells and inducing Th1 to Th2 shift in both cells and cytokines

(2008) Song Xinqiang et al.   VACCINE