Enteric formulated indole-3-carboxaldehyde targets the aryl hydrocarbon receptor for protection in a murine model of metabolic syndrome

Regulation of host physiology and immunity by microbial indole-3-aldehyde

(2021) Teresa Zelante et al.   CURRENT OPINION IN IMMUNOLOGY

Tryptophan Co-Metabolism at the Host-Pathogen Interface

(2020) Claudio Costantini et al.   Frontiers in Immunology

Net release and uptake of xenometabolites across intestinal, hepatic, muscle, and renal tissue beds in healthy conscious pigs

(2020) Kelly E. Mercer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Ageing, metabolism and the intestine

(2020) Maja C Funk et al.   EMBO REPORTS

Pyridoxal 5′-Phosphate-Dependent Enzymes at the Crossroads of Host–Microbe Tryptophan Metabolism

(2020) Barbara Cellini et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Microbial tryptophan metabolites regulate gut barrier function via the aryl hydrocarbon receptor

(2020) Samantha A. Scott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression

(2020) Ahmed Sadik et al.   CELL

Indoles from the commensal microbiota act via the AHR and IL-10 to tune the cellular composition of the colonic epithelium during aging

(2020) Domonica N. Powell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Environmental Sensor AHR Protects from Inflammatory Damage by Maintaining Intestinal Stem Cell Homeostasis and Barrier Integrity

(2019) Amina Metidji et al.   IMMUNITY

Targeting the Aryl Hydrocarbon Receptor With Indole-3-Aldehyde Protects From Vulvovaginal Candidiasis via the IL-22-IL-18 Cross-Talk

(2019) Monica Borghi et al.   Frontiers in Immunology

Targeting Aryl hydrocarbon receptor for next-generation immunotherapies: Selective modulators (SAhRMs) versus rapidly metabolized ligands (RMAhRLs)

(2019) Daniela Dolciami et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Fiber-Mediated Nourishment of Gut Microbiota Protects against Diet-Induced Obesity by Restoring IL-22-Mediated Colonic Health

(2018) Jun Zou et al.   Cell Host & Microbe

Regulation of the Immune Response by the Aryl Hydrocarbon Receptor

(2018) Cristina Gutiérrez-Vázquez et al.   IMMUNITY

Development of Novel Indole-3-Aldehyde–Loaded Gastro-Resistant Spray-Dried Microparticles for Postbiotic Small Intestine Local Delivery

(2018) Matteo Puccetti et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Genetic deficiency of indoleamine 2,3-dioxygenase promotes gut microbiota-mediated metabolic health

(2018) Ludivine Laurans et al.   NATURE MEDICINE

IL-9 and Mast Cells Are Key Players of Candida albicans Commensalism and Pathogenesis in the Gut

(2018) Giorgia Renga et al.   Cell Reports

Impact of the Gut Microbiota on Intestinal Immunity Mediated by Tryptophan Metabolism

(2018) Jing Gao et al.   Frontiers in Cellular and Infection Microbiology

Indoles derived from intestinal microbiota act via type I interferon signaling to limit Graft-versus-Host-Disease

(2018) Alyson Swimm et al.   BLOOD

Impaired Aryl Hydrocarbon Receptor Ligand Production by the Gut Microbiota Is a Key Factor in Metabolic Syndrome

(2018) Jane M. Natividad et al.   Cell Metabolism

Drying Technologies for the Stability and Bioavailability of Biopharmaceuticals

(2018) Fakhrossadat Emami et al.   Pharmaceutics

Indoles from commensal bacteria extend healthspan

(2017) Robert Sonowal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High Fat Diets Induce Colonic Epithelial Cell Stress and Inflammation that is Reversed by IL-22

(2016) Max Gulhane et al.   Scientific Reports

Inflammasomes of the intestinal epithelium

(2015) Mikael E. Sellin et al.   TRENDS IN IMMUNOLOGY

The Aryl Hydrocarbon Receptor: Multitasking in the Immune System

(2014) Brigitta Stockinger et al.   Annual Review of Immunology

Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22

(2013) Teresa Zelante et al.   IMMUNITY

Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases

(2012) Charles A. Dinarello et al.   NATURE REVIEWS DRUG DISCOVERY

A comprehensive definition for metabolic syndrome

(2009) P. L. Huang   Disease Models & Mechanisms