Ubiquitin-Specific Protease 3 Deubiquitinates and Stabilizes Oct4 Protein in Human Embryonic Stem Cells

Genome-scale screening of deubiquitinase subfamily identifies USP3 as a stabilizer of Cdc25A regulating cell cycle in cancer

(2020) Soumyadip Das et al.   CELL DEATH AND DIFFERENTIATION

Dynamical reorganization of the pluripotency transcription factors Oct4 and Sox2 during early differentiation of embryonic stem cells

(2020) Paula Verneri et al.   Scientific Reports

Bach1 regulates self-renewal and impedes mesendodermal differentiation of human embryonic stem cells

(2019) Xiangxiang Wei et al.   Science Advances

Ubiquitin-specific protease 3 promotes cell migration and invasion by interacting with and deubiquitinating SUZ12 in gastric cancer

(2019) Xiaosheng Wu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The cell cycle in stem cell proliferation, pluripotency and differentiation

(2019) Lijun Liu et al.   NATURE CELL BIOLOGY

USP3 promotes breast cancer cell proliferation by deubiquitinating KLF5

(2019) Yingying Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Post-translational modification of OCT4 in breast cancer tumorigenesis

(2018) Yunhee Cho et al.   CELL DEATH AND DIFFERENTIATION

Deubiquitinating enzymes in cancer stem cells: functions and targeted inhibition for cancer therapy

(2018) Kamini Kaushal et al.   DRUG DISCOVERY TODAY

Insights into the ubiquitin-proteasome system of human embryonic stem cells

(2018) Isabel Saez et al.   Scientific Reports

Regulation of pluripotency and differentiation by deubiquitinating enzymes

(2016) B Suresh et al.   CELL DEATH AND DIFFERENTIATION

SALL4, the missing link between stem cells, development and cancer

(2016) Hiro Tatetsu et al.   GENE

Concise Review: Fate Determination of Stem Cells by Deubiquitinating Enzymes

(2016) Arun Pandian Chandrasekaran et al.   STEM CELLS

Aurkb/PP1-mediated resetting of Oct4 during the cell cycle determines the identity of embryonic stem cells

(2016) Jihoon Shin et al.   eLife

The Importance of Ubiquitination and Deubiquitination in Cellular Reprogramming

(2016) Bharathi Suresh et al.   Stem Cells International

DPF2 regulates OCT4 protein level and nuclear distribution

(2015) Chao Liu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA

(2014) S. Ramakrishna et al.   GENOME RESEARCH

Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins

(2014) S. Kim et al.   GENOME RESEARCH

Protein quality control and elimination of protein waste: The role of the ubiquitin–proteasome system

(2013) Ingo Amm et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

High Dub3 Expression in Mouse ESCs Couples the G1/S Checkpoint to Pluripotency

(2013) Siem van der Laan et al.   MOLECULAR CELL

O-GlcNAc Regulates Pluripotency and Reprogramming by Directly Acting on Core Components of the Pluripotency Network

(2012) Hyonchol Jang et al.   Cell Stem Cell

UPS Delivers Pluripotency

(2012) Yasutaka Okita et al.   Cell Stem Cell

Regulation of Pluripotency and Cellular Reprogramming by the Ubiquitin-Proteasome System

(2012) Shannon M. Buckley et al.   Cell Stem Cell

Itch, an E3 ligase of Oct4, is required for embryonic stem cell self-renewal and pluripotency induction

(2012) Bing Liao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Post-translational modulation of pluripotency

(2012) Ning Cai et al.   Journal of Molecular Cell Biology

Loss of Pluripotency in Human Embryonic Stem Cells Directly Correlates with an Increase in Nuclear Zinc

(2010) Janet L. Wolford et al.   PLoS One

Human Embryonic Stem Cells are Capable of Executing G1/S Checkpoint Activation

(2010) Tomáš Bárta et al.   STEM CELLS

Depletion of Embryonic Stem Cell Signature by Histone Deacetylase Inhibitor in NCCIT Cells: Involvement of Nanog Suppression

(2009) J. S. You et al.   CANCER RESEARCH

Wwp2 mediates Oct4 ubiquitination and its own auto-ubiquitination in a dosage-dependent manner

(2009) Bing Liao et al.   CELL RESEARCH

Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly

(2009) H. J. Kim et al.   GENOME RESEARCH

A role for NANOG in G1 to S transition in human embryonic stem cells through direct binding of CDK6 and CDC25A

(2009) Xin Zhang et al.   JOURNAL OF CELL BIOLOGY

Post-Translational Regulation of Oct4 Transcriptional Activity

(2009) Jonathan P. Saxe et al.   PLoS One

Molecular basis of pluripotency

(2008) L. Chen et al.   HUMAN MOLECULAR GENETICS