NXP031 Improves Cognitive Impairment in a Chronic Cerebral Hypoperfusion-Induced Vascular Dementia Rat Model through Nrf2 Signaling

Microglial activation contributes to cognitive impairments in rotenone-induced mouse Parkinson’s disease model

(2021) Dongdong Zhang et al.   Journal of Neuroinflammation

NRF2 as a Therapeutic Target in Neurodegenerative Diseases

(2020) Mikah S. Brandes et al.   ASN Neuro

Ezetimibe Attenuates Oxidative Stress and Neuroinflammation via the AMPK/Nrf2/TXNIP Pathway after MCAO in Rats

(2020) Jing Yu et al.   Oxidative Medicine and Cellular Longevity

Multifaceted roles of pericytes in central nervous system homeostasis and disease

(2020) Zhitong Zheng et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Lactulose and Melibiose Attenuate MPTP-Induced Parkinson’s Disease in Mice by Inhibition of Oxidative Stress, Reduction of Neuroinflammation and Up-Regulation of Autophagy

(2020) Chih-Hsin Lin et al.   Frontiers in Aging Neuroscience

Neuroprotective Effect of Antioxidants in the Brain

(2020) Kyung Hee Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neuroprotective effect of NXP031 in the MPTP-induced Parkinson's disease model

(2020) Min Kyung Song et al.   NEUROSCIENCE LETTERS

Critical Role of Nrf2 in Experimental Ischemic Stroke

(2019) Lei Liu et al.   Frontiers in Pharmacology

Neuroprotective effect of Apelin 13 on ischemic stroke by activating AMPK/GSK-3β/Nrf2 signaling

(2019) Jialin Duan et al.   Journal of Neuroinflammation

Microglial activation after ischaemic stroke

(2019) Shengxiang Zhang   JOURNAL OF INVESTIGATIVE MEDICINE

Advances in dermatology using DNA aptamer “Aptamin C” innovation: Oxidative stress prevention and effect maximization of vitamin C through antioxidation

(2019) Sooho Choi et al.   Journal of Cosmetic Dermatology

Neurobiology of vitamin C: Expanding the focus from antioxidant to endogenous neuromodulator

(2019) Santiago J. Ballaz et al.   PHARMACOLOGICAL RESEARCH

Embelin Improves the Spatial Memory and Hippocampal Long-Term Potentiation in a Rat Model of Chronic Cerebral Hypoperfusion

(2019) Saatheeyavaane Bhuvanendran et al.   Scientific Reports

Resveratrol loaded solid lipid nanoparticles attenuate mitochondrial oxidative stress in vascular dementia by activating Nrf2/HO-1 pathway

(2018) Aarti Yadav et al.   NEUROCHEMISTRY INTERNATIONAL

DL-3-n-butylphthalide alleviates vascular cognitive impairment induced by chronic cerebral hypoperfusion by activating the Akt/Nrf2 signaling pathway in the hippocampus of rats

(2018) Qianqian Qi et al.   NEUROSCIENCE LETTERS

MicroRNA-26b Regulates the Microglial Inflammatory Response in Hypoxia/Ischemia and Affects the Development of Vascular Cognitive Impairment

(2018) Yuan-Cheng Kang et al.   Frontiers in Cellular Neuroscience

Chotosan ameliorates cognitive impairment and hippocampus neuronal loss in experimental vascular dementia via activating the Nrf2-mediated antioxidant pathway

(2018) Pan Jiang et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Dysfunction of Cerebrovascular Endothelial Cells: Prelude to Vascular Dementia

(2018) Feixue Wang et al.   Frontiers in Aging Neuroscience

Edaravone attenuates oxidative stress induced by chronic cerebral hypoperfusion injury: role of ERK/Nrf2/HO-1 signaling pathway

(2017) Dandan Zhang et al.   NEUROLOGICAL RESEARCH

Neuropathology of White Matter Lesions, Blood–Brain Barrier Dysfunction, and Dementia

(2017) Atticus H. Hainsworth et al.   STROKE

Protective Effect of 17β-Estradiol Upon Hippocampal Spine Density and Cognitive Function in an Animal Model of Vascular Dementia

(2017) Ying Zhu et al.   Scientific Reports

Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinson's Disease

(2016) Emma Deas et al.   ANTIOXIDANTS & REDOX SIGNALING

Vascular cognitive impairment and dementia

(2016) Philip B. Gorelick et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Vascular contributions to cognitive impairment, clinical Alzheimer's disease, and dementia in older persons

(2016) A. Kapasi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Stroke injury, cognitive impairment and vascular dementia

(2016) Raj N. Kalaria et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Protocatechualdehyde Protects Against Cerebral Ischemia-Reperfusion-Induced Oxidative Injury Via Protein Kinase Cε/Nrf2/HO-1 Pathway

(2016) Chao Guo et al.   MOLECULAR NEUROBIOLOGY

Nrf2—a Promising Therapeutic Target for Defensing Against Oxidative Stress in Stroke

(2016) Rongrong Zhang et al.   MOLECULAR NEUROBIOLOGY

(2R,3S)-Pinobanksin-3-cinnamate improves cognition and reduces oxidative stress in rats with vascular dementia

(2015) Hong Liu et al.   Journal of Natural Medicines

The role of lipid peroxidation in neurological disorders

(2014) Mototada Shichiri   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Docosahexaenoic acid and human brain development: Evidence that a dietary supply is needed for optimal development

(2014) J. Thomas Brenna et al.   JOURNAL OF HUMAN EVOLUTION

Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal

(2014) Antonio Ayala et al.   Oxidative Medicine and Cellular Longevity

Neuroprotection by Acetyl-11-Keto-β-Boswellic Acid, in Ischemic Brain Injury Involves the Nrf2/HO-1 defense Pathway

(2014) Yi Ding et al.   Scientific Reports

Role of Nrf2 in Oxidative Stress and Toxicity

(2013) Qiang Ma   Annual Review of Pharmacology and Toxicology

Change of Nrf2 expression in rat hippocampus in a model of chronic cerebral hypoperfusion

(2013) Ying Yang et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

4-Hydroxy-2-Nonenal, a Reactive Product of Lipid Peroxidation, and Neurodegenerative Diseases: A Toxic Combination Illuminated by Redox Proteomics Studies

(2011) Marzia Perluigi et al.   ANTIOXIDANTS & REDOX SIGNALING

Regulation of the Nrf2–Keap1 Antioxidant Response by the Ubiquitin Proteasome System: An Insight into Cullin-Ring Ubiquitin Ligases

(2010) Nicole F. Villeneuve et al.   ANTIOXIDANTS & REDOX SIGNALING

Review: Cerebral microvascular pathology in ageing and neurodegeneration

(2010) W. R. Brown et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Vitamin C protects against ethanol and PTZ-induced apoptotic neurodegeneration in prenatal rat hippocampal neurons

(2010) M.I. Naseer et al.   SYNAPSE

Blood-brain barrier tight junction permeability and ischemic stroke

(2008) Karin E. Sandoval et al.   NEUROBIOLOGY OF DISEASE