5-HT Receptors and the Development of New Antidepressants

Integrating Endocannabinoid Signalling In Depression

(2021) Tarapati Rana et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Effects of Subchronic Administrations of Vortioxetine, Lurasidone, and Escitalopram on Thalamocortical Glutamatergic Transmission Associated with Serotonin 5-HT7 Receptor

(2021) Motohiro Okada et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Current Limitations and Candidate Potential of 5-HT7 Receptor Antagonism in Psychiatric Pharmacotherapy

(2021) Ruri Okubo et al.   Frontiers in Psychiatry

5-HT4 Receptors Are Not Involved in the Effects of Fluoxetine in the Corticosterone Model of Depression

(2021) Josep Amigo et al.   ACS Chemical Neuroscience

Exploring Sonic Hedgehog Cell Signaling in Neurogenesis: Its Potential Role in Depressive Behavior

(2021) Tarapati Rana et al.   NEUROCHEMICAL RESEARCH

Elucidating the Possible Role of FoxO in Depression

(2021) Tarapati Rana et al.   NEUROCHEMICAL RESEARCH

Translating the promise of 5HT4 receptor agonists for the treatment of depression

(2020) Susannah E Murphy et al.   PSYCHOLOGICAL MEDICINE

Depressive-like state sensitizes 5-HT1A and 5-HT1B auto-receptors in the dorsal raphe nucleus sub-system

(2020) Xiang Li et al.   BEHAVIOURAL BRAIN RESEARCH

Is the bell-shaped dose-response curve of the selective serotonin reuptake inhibitor due to 5-HT1A auto-receptors?

(2020) Takeshi Terao et al.   MEDICAL HYPOTHESES

Unfolding the Role of BDNF as a Biomarker for Treatment of Depression

(2020) Tarapati Rana et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

NLX-101, a highly selective 5-HT1A receptor biased agonist, mediates antidepressant-like activity in rats via prefrontal cortex 5-HT1A receptors

(2020) R. Depoortère et al.   BEHAVIOURAL BRAIN RESEARCH

Monoaminergic system and depression

(2019) L. Perez-Caballero et al.   CELL AND TISSUE RESEARCH

Serotonin 5-HT1A Receptor Biased Agonists Display Differential Anxiolytic Activity in a Rat Social Interaction Model

(2019) Ronan Depoortère et al.   ACS Chemical Neuroscience

Adaptive mechanisms following antidepressant drugs: focus on serotonin 5-HT2A receptors

(2019) Dawid Gawliński et al.   Pharmacological Reports

Intravenous vortioxetine to accelerate onset of effect in major depressive disorder

(2019) Eduard Vieta et al.   INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY

Targeting Serotonin1A Receptors for Treating Chronic Pain and Depression

(2019) Darakhshan Jabeen Haleem   Current Neuropharmacology

Sustained Activation of Postsynaptic 5-HT2A Receptors Gates Plasticity at Prefrontal Cortex Synapses

(2018) Coralie Berthoux et al.   CEREBRAL CORTEX

Can we increase speed and efficacy of antidepressant treatments? Part I: General aspects and monoamine-based strategies

(2018) Francesc Artigas et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Serotonin 5-HT 3 receptor antagonism potentiates the antidepressant activity of citalopram

(2018) Blanca Perez-Palomar et al.   NEUROPHARMACOLOGY

Activation of 5-HT 2A receptor disrupts rat maternal behavior

(2018) Jun Gao et al.   NEUROPHARMACOLOGY

Positive regulation of raphe serotonin neurons by serotonin 2B receptors

(2018) Arnauld Belmer et al.   NEUROPSYCHOPHARMACOLOGY

The 5-HT1B receptor - a potential target for antidepressant treatment

(2018) Mikael Tiger et al.   PSYCHOPHARMACOLOGY

Serotonin receptors in depression and anxiety: Insights from animal studies

(2018) Elżbieta Żmudzka et al.   LIFE SCIENCES

5-HT2C receptor blockade reverses SSRI-associated basal ganglia dysfunction and potentiates therapeutic efficacy

(2018) Elena Y. Demireva et al.   MOLECULAR PSYCHIATRY

The 5-HT1A receptor: Signaling to behavior

(2018) Paul R. Albert et al.   BIOCHIMIE

Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2018) Spencer L James et al.   LANCET

Restoring function in major depressive disorder: A systematic review

(2017) David V. Sheehan et al.   JOURNAL OF AFFECTIVE DISORDERS

Abrogated Freud-1/Cc2d1a Repression of 5-HT1A Autoreceptors Induces Fluoxetine-Resistant Anxiety/Depression-Like Behavior

(2017) Faranak Vahid-Ansari et al.   JOURNAL OF NEUROSCIENCE

Vortioxetine: A review of the pharmacology and clinical profile of the novel antidepressant

(2017) Magdalena Sowa-Kućma et al.   Pharmacological Reports

The Effect of Serotonin-Targeting Antidepressants on Neurogenesis and Neuronal Maturation of the Hippocampus Mediated via 5-HT1A and 5-HT4 Receptors

(2017) Eri Segi-Nishida   Frontiers in Cellular Neuroscience

A novel 5HT3 antagonist 4i (N-(3-chloro-2-methylphenyl)quinoxalin-2-carboxamide) prevents diabetes-induced depressive phenotypes in mice: Modulation of serotonergic system

(2016) Deepali Gupta et al.   BEHAVIOURAL BRAIN RESEARCH

Hesperidin reverses cognitive and depressive disturbances induced by olfactory bulbectomy in mice by modulating hippocampal neurotrophins and cytokine levels and acetylcholinesterase activity

(2016) Michelle S. Antunes et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Involvement of nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of tropisetron and ondansetron in mice forced swimming test and tail suspension test

(2016) Arya Haj-Mirzaian et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mice lacking the serotonin 5-HT 2B receptor as an animal model of resistance to selective serotonin reuptake inhibitors antidepressants

(2016) Silvina Laura Diaz et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

The 5-HT1A receptor in Major Depressive Disorder

(2016) Joshua Kaufman et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

The Preclinical and Clinical Effects of Vilazodone for the Treatment of Major Depressive Disorder

(2016) Zeyad T. Sahli et al.   Expert Opinion on Drug Discovery

The absence of 5-HT4 receptors modulates depression- and anxiety-like responses and influences the response of fluoxetine in olfactory bulbectomised mice: Adaptive changes in hippocampal neuroplasticity markers and 5-HT1A autoreceptor

(2016) J. Amigó et al.   NEUROPHARMACOLOGY

A Lack of Serotonin 1B Autoreceptors Results in Decreased Anxiety and Depression-Related Behaviors

(2016) Katherine M Nautiyal et al.   NEUROPSYCHOPHARMACOLOGY

5HT3 receptors: Target for new antidepressant drugs

(2016) Deepali Gupta et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Chronic 5-HT4 receptor agonist treatment restores learning and memory deficits in a neuroendocrine mouse model of anxiety/depression

(2016) Flavie Darcet et al.   NEUROSCIENCE LETTERS

The role of serotonergic, adrenergic and dopaminergic receptors in antidepressant-like effect

(2016) Karolina Pytka et al.   Pharmacological Reports

Involvement of N-methyl-d-aspartate receptors in the antidepressant-like effect of 5-hydroxytryptamine 3 antagonists in mouse forced swimming test and tail suspension test

(2016) Nastaran Kordjazy et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Aripiprazole Augmentation in Major Depressive Disorder: A Double-Blind, Placebo-Controlled Study in Patients with Inadequate Response to Antidepressants

(2016) Robert M. Berman et al.   CNS SPECTRUMS

Piperazine Analogs of Naphthyridine-3-carboxamides and Indole-2-carboxamides: Novel 5-HT3Receptor Antagonists with Antidepressant-Like Activity

(2015) Arghya K. Dhar et al.   ARCHIV DER PHARMAZIE

The atypical antipsychotics clozapine and olanzapine promote down-regulation and display functional selectivity at human 5-HT7receptors

(2015) K W Andressen et al.   BRITISH JOURNAL OF PHARMACOLOGY

Developments in the field of antidepressants, where do we go now?

(2015) Francesc Artigas   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Evidence-based guidelines for treating depressive disorders with antidepressants: A revision of the 2008 British Association for Psychopharmacology guidelines

(2015) Anthony Cleare et al.   JOURNAL OF PSYCHOPHARMACOLOGY

5-HT1A receptors on mature dentate gyrus granule cells are critical for the antidepressant response

(2015) Benjamin Adam Samuels et al.   NATURE NEUROSCIENCE

Antidepressant-like activity of EMD 386088, a 5-HT6 receptor partial agonist, following systemic acute and chronic administration to rats

(2015) Magdalena Jastrzębska-Więsek et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Chronic unpredictable mild stress decreases BDNF and NGF levels and Na+,K+-ATPase activity in the hippocampus and prefrontal cortex of mice: Antidepressant effect of chrysin

(2015) C.B. Filho et al.   NEUROSCIENCE

Structure and function of serotonin G protein-coupled receptors

(2015) John D. McCorvy et al.   PHARMACOLOGY & THERAPEUTICS

Vortioxetine, a novel antidepressant with multimodal activity: Review of preclinical and clinical data

(2015) Connie Sanchez et al.   PHARMACOLOGY & THERAPEUTICS

Effect of a novel 5-HT 3 receptor antagonist 4i, in corticosterone-induced depression-like behavior and oxidative stress in mice

(2015) Deepali Gupta et al.   STEROIDS

5-HT6 receptor agonism facilitates emotional learning

(2015) Marcela Pereira et al.   Frontiers in Pharmacology

Profile of vortioxetine in the treatment of major depressive disorder: an overview of the primary and secondary literature

(2015) William Bobo et al.   Therapeutics and Clinical Risk Management

Serotonin 5-HT4 Receptors: A New Strategy for Developing Fast Acting Antidepressants?

(2014) Rebeca Vidal et al.   CURRENT PHARMACEUTICAL DESIGN

Antidepressant and anti-anxiety like effects of 4i (N-(3-chloro-2-methylphenyl) quinoxalin-2-carboxamide), a novel 5-HT3 receptor antagonist in acute and chronic neurobehavioral rodent models

(2014) Deepali Gupta et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Ondansetron, a 5HT3 receptor antagonist reverses depression and anxiety-like behavior in streptozotocin-induced diabetic mice: Possible implication of serotonergic system

(2014) Deepali Gupta et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

A review of the clinical efficacy, safety and tolerability of the antidepressants vilazodone, levomilnacipran and vortioxetine

(2014) William James Deardorff et al.   EXPERT OPINION ON PHARMACOTHERAPY

Antidepressant-like effects of Xiaochaihutang in a rat model of chronic unpredictable mild stress

(2014) Guang Yue Su et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cdk5 induces constitutive activation of 5-HT6 receptors to promote neurite growth

(2014) Fanny Duhr et al.   Nature Chemical Biology

Significantly decreased mRNA levels of BDNF and MEK1 genes in treatment-resistant depression

(2014) Wu Hong et al.   NEUROREPORT

Serotonin 1A and Serotonin 4 Receptors

(2014) Benjamin Adam Samuels et al.   NEUROSCIENTIST

5HT3 receptor antagonist (ondansetron) reverses depressive behavior evoked by chronic unpredictable stress in mice: Modulation of hypothalamic–pituitary–adrenocortical and brain serotonergic system

(2014) Deepali Gupta et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Allowing for non-adherence to treatment in a randomized controlled trial of two antidepressants (citalopram versus reboxetine): an example from the GENPOD trial

(2014) N. J. Wiles et al.   PSYCHOLOGICAL MEDICINE

Brain Serotonin 1A Receptor Binding as a Predictor of Treatment Outcome in Major Depressive Disorder

(2013) Jeffrey M. Miller et al.   BIOLOGICAL PSYCHIATRY

2-Amino-6-chloro-3,4-dihydroquinazoline: A novel 5-HT3 receptor antagonist with antidepressant character

(2013) Małgorzata Dukat et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

5-Hydroxytryptamine 2A receptor antagonists as potential treatment for psychiatric disorders

(2013) Tiago A Mestre et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

On ‘polypharmacy’ and multi-target agents, complementary strategies for improving the treatment of depression: a comparative appraisal

(2013) Mark J. Millan   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

QCM-4 a novel 5-HT3antagonist attenuates the behavioral and biochemical alterations on chronic unpredictable mild stress model of depression in Swiss albino mice

(2013) Yeshwant Kurhe et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Rapid Anxiolytic Effects of a 5-HT4 Receptor Agonist Are Mediated by a Neurogenesis-Independent Mechanism

(2013) Indira Mendez-David et al.   NEUROPSYCHOPHARMACOLOGY

Vortioxetine (Lu AA21004), a novel multimodal antidepressant, enhances memory in rats

(2013) Arne Mørk et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Serotonin and beyond: therapeutics for major depression

(2013) P. Blier et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The rapid recovery of 5-HT cell firing induced by the antidepressant vortioxetine involves 5-HT3 receptor antagonism

(2012) Cécile Bétry et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Effects of Sustained Administration of Quetiapine Alone and in Combination with a Serotonin Reuptake Inhibitor on Norepinephrine and Serotonin Transmission

(2012) Olga Chernoloz et al.   NEUROPSYCHOPHARMACOLOGY

Serotonin receptors involved in antidepressant effects

(2012) Francesc Artigas   PHARMACOLOGY & THERAPEUTICS

Biased agonism at serotonin 5-HT1A receptors: preferential postsynaptic activity for improved therapy of CNS disorders

(2012) Adrian Newman-Tancredi   Neuropsychiatry

Serotonin and GI Disorders: An Update on Clinical and Experimental Studies

(2012) Marcus Manocha et al.   Clinical and Translational Gastroenterology

Preclinical and clinical characterization of the selective 5-HT1Areceptor antagonist DU-125530 for antidepressant treatment

(2011) MC Scorza et al.   BRITISH JOURNAL OF PHARMACOLOGY

5-HT and depression: is the glass half-full?

(2011) Trevor Sharp et al.   CURRENT OPINION IN PHARMACOLOGY

New Strategies in the Development of Antidepressants: Towards the Modulation of Neuroplasticity Pathways

(2011) Rebeca Vidal et al.   CURRENT PHARMACEUTICAL DESIGN

A randomised, double-blind, placebo controlled, duloxetine-referenced, fixed-dose study of three dosages of Lu AA21004 in acute treatment of major depressive disorder (MDD)

(2011) David S. Baldwin et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

A double-blind, randomized, placebo-controlled, active reference study of Lu AA21004 in patients with major depressive disorder

(2011) Enric Alvarez et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

A 1-Year, Open-Label Study Assessing the Safety and Tolerability of Vilazodone in Patients With Major Depressive Disorder

(2011) Donald S. Robinson et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Serotonin-1A Autoreceptors Are Necessary and Sufficient for the Normal Formation of Circuits Underlying Innate Anxiety

(2011) J. W. Richardson-Jones et al.   JOURNAL OF NEUROSCIENCE

Toward Selective Drug Development for the Human 5-Hydroxytryptamine 1E Receptor: A Comparison of 5-Hydroxytryptamine 1E and 1F Receptor Structure-Affinity Relationships

(2011) M. T. Klein et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Vilazodone

(2011)   JOURNAL OF PSYCHOSOCIAL NURSING AND MENTAL HEALTH SERVICES

5-HT2B receptors are required for serotonin-selective antidepressant actions

(2011) S L Diaz et al.   MOLECULAR PSYCHIATRY

Co-expression of serotonin 5-HT1B and 5-HT4 receptors in p11 containing cells in cerebral cortex, hippocampus, caudate-putamen and cerebellum

(2011) Martin Egeland et al.   NEUROPHARMACOLOGY

Epigenetic Treatments for Cognitive Impairments

(2011) Jeremy J Day et al.   NEUROPSYCHOPHARMACOLOGY

5-HT2C Receptors Localize to Dopamine and GABA Neurons in the Rat Mesoaccumbens Pathway

(2011) Marcy J. Bubar et al.   PLoS One

The 5-HT6 receptor agonist EMD 386088 produces antidepressant and anxiolytic effects in rats after intrahippocampal administration

(2011) Agnieszka Nikiforuk et al.   PSYCHOPHARMACOLOGY

Transcriptional dysregulation of 5-HT1A autoreceptors in mental illness

(2011) Paul R Albert et al.   Molecular Brain

Long-term treatment with peony glycosides reverses chronic unpredictable mild stress-induced depressive-like behavior via increasing expression of neurotrophins in rat brain

(2010) Qing-Qiu Mao et al.   BEHAVIOURAL BRAIN RESEARCH

Reduced signal transduction by 5-HT4 receptors after long-term venlafaxine treatment in rats

(2010) R Vidal et al.   BRITISH JOURNAL OF PHARMACOLOGY

Unraveling Monoamine Receptors Involved in the Action of Typical and Atypical Antipsychotics on Glutamatergic and Serotonergic Transmission in Prefrontal Cortex

(2010) Xavier Lopez-Gil et al.   CURRENT PHARMACEUTICAL DESIGN

5-HT6 Receptor Antagonists as Potential Therapeutics for Cognitive Impairment

(2010) Gerard Rosse et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

F15599, a highly selective post-synaptic 5-HT1A receptor agonist: in-vivo profile in behavioural models of antidepressant and serotonergic activity

(2010) Marie-Bernadette Assié et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

The Serotonin-7 Receptor as a Novel Therapeutic Target

(2010) Stephen M. Stahl   JOURNAL OF CLINICAL PSYCHIATRY

Changes in 5-HT4 receptor and 5-HT transporter binding in olfactory bulbectomized and glucocorticoid receptor heterozygous mice

(2010) Cecilie L. Licht et al.   NEUROCHEMISTRY INTERNATIONAL

Brain imaging of serotonin 4 receptors in humans with [11C]SB207145-PET

(2010) Lisbeth Marner et al.   NEUROIMAGE

5-HT1A Autoreceptor Levels Determine Vulnerability to Stress and Response to Antidepressants

(2010) Jesse W. Richardson-Jones et al.   NEURON

The role of serotonin receptor subtypes in treating depression: a review of animal studies

(2010) Gregory V. Carr et al.   PSYCHOPHARMACOLOGY

Antidepressant-like effects of serotonin type-3 antagonist, ondansetron: an investigation in behaviour-based rodent models

(2009) Rajkumar Ramamoorthy et al.   BEHAVIOURAL PHARMACOLOGY

The 5-HT1B Receptor: A Novel Target for the Pathophysiology of Depression (Supplementary Tables)

(2009) B. Ruf et al.   CURRENT DRUG TARGETS

Agonist-dependent modulation of G-protein coupling and transduction of 5-HT1A receptors in rat dorsal raphe nucleus

(2009) Elsa Maria Valdizán et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

The brain 5-HT4receptor binding is down-regulated in the Flinders Sensitive Line depression model and in response to paroxetine administration

(2009) Cecilie L. Licht et al.   JOURNAL OF NEUROCHEMISTRY

Role of p11 in Cellular and Behavioral Effects of 5-HT4 Receptor Stimulation

(2009) J. L. Warner-Schmidt et al.   JOURNAL OF NEUROSCIENCE

5-HT1A receptor function in major depressive disorder

(2009) Jonathan Savitz et al.   PROGRESS IN NEUROBIOLOGY

Electrophysiological studies in the rat brain on the basis for aripiprazole augmentation of antidepressants in major depressive disorder

(2009) Olga Chernoloz et al.   PSYCHOPHARMACOLOGY

Amisulpride is a potent 5-HT7 antagonist: relevance for antidepressant actions in vivo

(2009) Atheir I. Abbas et al.   PSYCHOPHARMACOLOGY

The 5-HT7 receptor and disorders of the nervous system: an overview

(2009) Peter B. Hedlund   PSYCHOPHARMACOLOGY

Modulation of cholinergic functions by serotonin and possible implications in memory: General data and focus on 5-HT1A receptors of the medial septum

(2008) Hélène Jeltsch-David et al.   BEHAVIOURAL BRAIN RESEARCH

Molecular biology of 5-HT receptors

(2008) Jason Hannon et al.   BEHAVIOURAL BRAIN RESEARCH

The role of 5-HT1A receptors in learning and memory

(2008) Sven Ove Ögren et al.   BEHAVIOURAL BRAIN RESEARCH

Posterior Hippocampal Volumes Are Associated with Remission Rates in Patients with Major Depressive Disorder

(2008) Glenda M. MacQueen et al.   BIOLOGICAL PSYCHIATRY

The Role of 5-HT3 Receptors in Drug Abuse and as a Target for Pharmacotherapy

(2008) E. Engleman et al.   CNS & Neurological Disorders-Drug Targets

Augmentation strategies for treatment-resistant depression

(2008) André F Carvalho et al.   CURRENT OPINION IN PSYCHIATRY

The selective 5-HT6 receptor antagonist SB-399885 enhances anti-immobility action of antidepressants in rats

(2008) Anna Wesołowska et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

What do we know about serotonin?

(2008) Catherine Jonnakuty et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Chronic Fluoxetine Bidirectionally Modulates Potentiating Effects of Serotonin on the Hippocampal Mossy Fiber Synaptic Transmission

(2008) K. Kobayashi et al.   JOURNAL OF NEUROSCIENCE

Pindolol augmentation of serotonin reuptake inhibitors for the treatment of depressive disorder: a systematic review

(2008) R. Whale et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Evidence for HTR1A and LHPP as interacting genetic risk factors in major depression

(2008) C D Neff et al.   MOLECULAR PSYCHIATRY

S32006, a novel 5-HT2C receptor antagonist displaying broad-based antidepressant and anxiolytic properties in rodent models

(2008) Anne Dekeyne et al.   PSYCHOPHARMACOLOGY

Fluoxetine-mediated 5-HT2B receptor stimulation in astrocytes causes EGF receptor transactivation and ERK phosphorylation

(2008) Baoman Li et al.   PSYCHOPHARMACOLOGY

Inactivation of the 5-HT7 Receptor Partially Blocks Phencyclidine-Induced Disruption of Prepulse Inhibition

(2007) Svetlana Semenova et al.   BIOLOGICAL PSYCHIATRY

Serotonin-1A autoreceptor binding in the dorsal raphe nucleus of depressed suicides

(2007) Maura Boldrini et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Selective 5-HT6 receptor ligands: Progress in the development of a novel pharmacological approach to the treatment of obesity and related metabolic disorders

(2007) D.J. Heal et al.   PHARMACOLOGY & THERAPEUTICS