Antidepressant-like activity of EMD 386088, a 5-HT6 receptor partial agonist, following systemic acute and chronic administration to rats
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Title
Antidepressant-like activity of EMD 386088, a 5-HT6 receptor partial agonist, following systemic acute and chronic administration to rats
Authors
Keywords
Depression, 5-HT<sub>6</sub> receptor agonist, Forced swim test, Olfactory bulbectomy model, Rats
Journal
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
Volume 388, Issue 10, Pages 1079-1088
Publisher
Springer Nature
Online
2015-06-15
DOI
10.1007/s00210-015-1141-2
References
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Note: Only part of the references are listed.- Pharmacological evaluation of the anxiolytic-like effects of EMD 386088, a partial 5-HT6 receptor agonist, in the rat elevated plus-maze and Vogel conflict tests
- (2014) Magdalena Jastrzębska-Więsek et al. NEUROPHARMACOLOGY
- Potential antidepressant-like effect of the potent serotonin 5-HT6 receptor agonist EMD 386088 in the forced swim test in rats
- (2014) Magdalena Jastrzębska-Więsek et al. Pharmacological Reports
- Partial agonist efficacy of EMD386088, a 5-HT6 receptor ligand, in functional in vitro assays
- (2014) Magdalena Jastrzębska-Więsek et al. Pharmacological Reports
- The 5-hydroxytryptamine (serotonin) receptor 6 agonist EMD 386088 ameliorates ketamine-induced deficits in attentional set shifting and novel object recognition, but not in the prepulse inhibition in rats
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- Procognitive 5-HT6 antagonists in the rat forced swimming test: Potential therapeutic utility in mood disorders associated with Alzheimer's disease
- (2009) Kazufumi Hirano et al. LIFE SCIENCES
- Activation of 5-HT6 receptors facilitates attentional set shifting
- (2009) Katherine E. Burnham et al. PSYCHOPHARMACOLOGY
- The effects of the 5-HT6 receptor agonist EMD and the 5-HT7 receptor agonist AS19 on memory formation
- (2008) A. Meneses et al. BEHAVIOURAL BRAIN RESEARCH
- An update on the role of the 5-hydroxytryptamine6 receptor in cognitive function
- (2008) Kevin C.F. Fone NEUROPHARMACOLOGY
- The anxiolytic-like effect of the selective 5-HT6 receptor antagonist SB-399885: The impact of benzodiazepine receptors
- (2007) Anna Wesołowska EUROPEAN JOURNAL OF PHARMACOLOGY
- Selective 5-HT6 receptor ligands: Progress in the development of a novel pharmacological approach to the treatment of obesity and related metabolic disorders
- (2007) D.J. Heal et al. PHARMACOLOGY & THERAPEUTICS
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