Different Expressions of HIF-1α and Metabolism in Brain and Major Visceral Organs of Acute Hypoxic Mice

Metabolic derangements of skeletal muscle from a murine model of glioma cachexia

(2019) Pengfei Cui et al.   Skeletal Muscle

Hypoxia and Hypoxia-Inducible Factors in Kidney Injury and Repair

(2019) Shaoqun Shu et al.   Cells

NAD(H) and NADP(H) Redox Couples and Cellular Energy Metabolism

(2018) Wusheng Xiao et al.   ANTIOXIDANTS & REDOX SIGNALING

Perturbations of Native Membrane Protein Structure in Alkyl Phosphocholine Detergents: A Critical Assessment of NMR and Biophysical Studies

(2018) Christophe Chipot et al.   CHEMICAL REVIEWS

The PHD1 oxygen sensor in health and disease

(2018) Kilian B. Kennel et al.   JOURNAL OF PHYSIOLOGY-LONDON

Hypoxia regulates the level of glutamic acid decarboxylase enzymes and interrupts inhibitory synapse stability in primary cultured neurons

(2018) Seojin Hwang et al.   NEUROTOXICOLOGY

Branched-chain amino acids in health and disease: metabolism, alterations in blood plasma, and as supplements

(2018) Milan Holeček   Nutrition & Metabolism

Upregulation of Krebs cycle and anaerobic glycolysis activity early after onset of liver ischemia

(2018) Tom S. Chan et al.   PLoS One

Hypobaric hypoxia induced renal damage is mediated by altering redox pathway

(2018) Varun Chhabra et al.   PLoS One

Glutamate as a potential “survival factor” in an in vitro model of neuronal hypoxia/reoxygenation injury: leading role of the Na+/Ca2+ exchanger

(2018) Silvia Piccirillo et al.   Cell Death & Disease

Acute Mild Hypoxic Hypoxia Effects on Cognitive and Simulated Aircraft Pilot Performance

(2018) Fethi Bouak et al.   Aerospace Medicine and Human Performance

Pre-clinical and clinical investigations of metabolic zonation in liver diseases: The potential of microphysiology systems

(2017) Alejandro Soto-Gutierrez et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

High concentration of branched-chain amino acids promotes oxidative stress, inflammation and migration of human peripheral blood mononuclear cells via mTORC1 activation

(2017) Olha Zhenyukh et al.   FREE RADICAL BIOLOGY AND MEDICINE

Alteration of Spontaneous Brain Activity After Hypoxia–Reoxygenation: A Resting-State fMRI Study

(2017) Jiaxing Zhang et al.   HIGH ALTITUDE MEDICINE & BIOLOGY

Insight into potential mechanisms of hypobaric hypoxia–induced learning and memory deficit – Lessons from rat studies

(2017) EYA Qaid et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Higher prevalence of unrecognized kidney disease at high altitude

(2017) Abdias Hurtado-Arestegui et al.   JOURNAL OF NEPHROLOGY

UPLC-QTOFMS-based metabolomic analysis of the serum of hypoxic preconditioning mice

(2017) Jie Liu et al.   Molecular Medicine Reports

Combination of NAD+ and NADPH Offers Greater Neuroprotection in Ischemic Stroke Models by Relieving Metabolic Stress

(2017) Qiao Huang et al.   MOLECULAR NEUROBIOLOGY

Hypoxia induces heart regeneration in adult mice

(2017) Yuji Nakada et al.   NATURE

Branched-Chain Amino Acids and Brain Metabolism

(2017) Justin E. Sperringer et al.   NEUROCHEMICAL RESEARCH

Brain adaptation to hypoxia and hyperoxia in mice

(2017) Laura Terraneo et al.   Redox Biology

Essential role of the Na+-Ca2+ exchanger (NCX) in glutamate-enhanced cell survival in cardiac cells exposed to hypoxia/reoxygenation

(2017) Marta Maiolino et al.   Scientific Reports

Cardiogenic Shock: Failure of Oxygen Delivery and Oxygen Utilization

(2016) Hoong Sern Lim   CLINICAL CARDIOLOGY

Hepatic glucose and lipid metabolism

(2016) John G. Jones   DIABETOLOGIA

Antioxidant Mechanism of Betaine without Free Radical Scavenging Ability

(2016) Mengmeng Zhang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Hypoxia and GABA shunt activation in the pathogenesis of Alzheimer's disease

(2016) Antero Salminen et al.   NEUROCHEMISTRY INTERNATIONAL

Oxygen–glucose deprivation enhancement of cell death/apoptosis in PC12 cells and hippocampal neurons correlates with changes in neuronal excitatory amino acid neurotransmitter signaling and potassium currents

(2016) Yu-Xiang Wang et al.   NEUROREPORT

SnapShot: Hypoxia-Inducible Factors

(2015) Kyoung Eun Lee et al.   CELL

Pathophysiology and Treatment of High-Altitude Pulmonary Vascular Disease

(2015) M. R. Wilkins et al.   CIRCULATION

Glutamate as a neurotransmitter in the healthy brain

(2014) Y. Zhou et al.   JOURNAL OF NEURAL TRANSMISSION

Hypoxia and fatty liver

(2014) Tomohiro Suzuki   WORLD JOURNAL OF GASTROENTEROLOGY

Glutathione and mitochondria

(2014) Vicent Ribas et al.   Frontiers in Pharmacology

Oxygen Sensing, Hypoxia-Inducible Factors, and Disease Pathophysiology

(2013) Gregg L. Semenza   Annual Review of Pathology-Mechanisms of Disease

Betaine Transport in Kidney and Liver: Use of Betaine in Liver Injury

(2013) Stephen A. Kempson et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

1H NMR Derived Metabolomic Profile of Neonatal Asphyxia in Umbilical Cord Serum: Implications for Hypoxic Ischemic Encephalopathy

(2013) Stacey N. Reinke et al.   JOURNAL OF PROTEOME RESEARCH

Blunted Myocardial Oxygenation Response During Vasodilator Stress in Patients With Hypertrophic Cardiomyopathy

(2013) Theodoros D. Karamitsos et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Short-term responses of the kidney to high altitude in mountain climbers

(2013) A. S. Goldfarb-Rumyantzev et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Adaptive Modulation of Adult Brain Gray and White Matter to High Altitude: Structural MRI Studies

(2013) Jiaxing Zhang et al.   PLoS One

Betaine reduces the expression of inflammatory adipokines caused by hypoxia in human adipocytes

(2012) K. Olli et al.   BRITISH JOURNAL OF NUTRITION

Compromised White Matter Microstructural Integrity after Mountain Climbing: Evidence from Diffusion Tensor Imaging

(2012) Haiyan Zhang et al.   HIGH ALTITUDE MEDICINE & BIOLOGY

Novel links between HIFs, type 2 diabetes, and metabolic syndrome

(2012) Christian M. Girgis et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Reductive carboxylation supports growth in tumour cells with defective mitochondria

(2011) Andrew R. Mullen et al.   NATURE

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

(2011) Christian M. Metallo et al.   NATURE

The Asparaginyl Hydroxylase Factor Inhibiting HIF-1α Is an Essential Regulator of Metabolism

(2010) Na Zhang et al.   Cell Metabolism

Hypoxia-mediated biological control

(2010) Jessica Cassavaugh et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Hypoxia-Inducible Factors and the Response to Hypoxic Stress

(2010) Amar J. Majmundar et al.   MOLECULAR CELL

Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes

(2010) Robert B. Hamanaka et al.   TRENDS IN BIOCHEMICAL SCIENCES

HIF-1α is necessary to support gluconeogenesis during liver regeneration

(2009) Toshihide Tajima et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Anti-HIF-1α antibody-conjugated pluronic triblock copolymers encapsulated with Paclitaxel for tumor targeting therapy

(2009) Hua Song et al.   BIOMATERIALS

Ablation of ARNT/HIF1β in Liver Alters Gluconeogenesis, Lipogenic Gene Expression, and Serum Ketones

(2009) Xiaohui L. Wang et al.   Cell Metabolism

Chronic Kidney Disease at High Altitude

(2008) A. M. Luks et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY