A Review of Honeybee Venom Allergens and Allergenicity

The Honeybee Venom Major Allergen Api m 10 (Icarapin) and Its Role in Diagnostics and Treatment of Hymenoptera Venom Allergy

(2020) Thilo Jakob et al.   CURRENT ALLERGY AND ASTHMA REPORTS

The Unique Protein Composition of Honey Revealed by Comprehensive Proteomic Analysis: Allergens, Venom-like Proteins, Antibacterial Properties, Royal Jelly Proteins, Serine Proteases, and Their Inhibitors

(2019) Tomas Erban et al.   JOURNAL OF NATURAL PRODUCTS

Hymenoptera Venom Allergy: How Does Venom Immunotherapy Prevent Anaphylaxis From Bee and Wasp Stings?

(2019) Umit Murat Sahiner et al.   Frontiers in Immunology

Risk factors for severe systemic sting reactions in wasp (Vespula spp.) and honeybee (Apis mellifera) venom allergic patients

(2019) Danielle Fehr et al.   Clinical and Translational Allergy

Sensitization to Hymenoptera venom marker allergens: Prevalence, predisposing factors, and clinical implications

(2018) Johanna Stoevesandt et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Insect venom phospholipases A1 and A2: Roles in the envenoming process and allergy

(2018) Amilcar Perez-Riverol et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Anaphylaxis in Poland: the epidemiology and direct costs

(2017) Karina Jahnz-Rozyk et al.   Postepy Dermatologii i Alergologii

Safety and efficacy of venom immunotherapy: a real life study

(2017) Agnieszka Kołaczek et al.   Postepy Dermatologii i Alergologii

Honey: Chemical composition, stability and authenticity

(2016) Priscila Missio da Silva et al.   FOOD CHEMISTRY

Predominant Api m 10 sensitization as risk factor for treatment failure in honey bee venom immunotherapy

(2016) Marcel Frick et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Impact of Bee Venom Enzymes on Diseases and Immune Responses

(2016) Md. Hossen et al.   MOLECULES

Melittin, the Major Pain-Producing Substance of Bee Venom

(2016) Jun Chen et al.   Neuroscience Bulletin

rApi m 3 and rApi m 10 improve detection of honey bee sensitization in Hymenoptera venom-allergic patients with double sensitization to honey bee and yellow jacket venom

(2015) M. Frick et al.   ALLERGY

IgE recognition of chimeric isoforms of the honeybee (Apis mellifera) venom allergen Api m 10 evaluated by protein array technology

(2015) Matthias Van Vaerenbergh et al.   MOLECULAR IMMUNOLOGY

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

Component resolution reveals additional major allergens in patients with honeybee venom allergy

(2014) Julian Köhler et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Exploring the hidden honeybee (Apis mellifera) venom proteome by integrating a combinatorial peptide ligand library approach with FTMS

(2014) Matthias Van Vaerenbergh et al.   Journal of Proteomics

Functional characterization of naturally occurring melittin peptide isoforms in two honey bee species, Apis mellifera and Apis cerana

(2014) Doori Park et al.   PEPTIDES

Contribution of botanical origin and sugar composition of honeys on the crystallization phenomenon

(2013) Olga Escuredo et al.   FOOD CHEMISTRY

Non-ST segment elevation myocardial infarction after multiple bee stings. A case of “delayed” Kounis II syndrome?

(2013) Marita Nittner-Marszalska et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

IgG4 production is confined to human IL-10–producing regulatory B cells that suppress antigen-specific immune responses

(2013) Willem van de Veen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Sensitization to Hymenoptera venoms is common, but systemic sting reactions are rare

(2013) Gunter J. Sturm et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Vitellogenins Are New High Molecular Weight Components and Allergens (Api m 12 and Ves v 6) of Apis mellifera and Vespula vulgaris Venom

(2013) Simon Blank et al.   PLoS One

Management of Insect Sting Hypersensitivity: An Update

(2013) Robert D. Pesek et al.   Allergy Asthma & Immunology Research

The major royal jelly proteins 8 and 9 (Api m 11) are glycosylated components ofApis melliferavenom with allergenic potential beyond carbohydrate-based reactivity

(2012) S. Blank et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Direct potentiometric determination of diastase activity in honey

(2012) Milan Sak-Bosnar et al.   FOOD CHEMISTRY

Api m 10, a genuine A. mellifera venom allergen, is clinically relevant but underrepresented in therapeutic extracts

(2011) S. Blank et al.   ALLERGY

Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention

(2011) Edward A. Dennis et al.   CHEMICAL REVIEWS

Safety of hymenoptera venom immunotherapy: a systematic review

(2011) Cristoforo Incorvaia et al.   EXPERT OPINION ON PHARMACOTHERAPY

Detection of IgE to recombinant Api m 1 and rVes v 5 is valuable but not sufficient to distinguish bee from wasp venom allergy

(2011) Gunter J. Sturm et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Low sensitivity of commercially available rApi m 1 for diagnosis of honeybee venom allergy

(2011) Peter Korošec et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mechanisms of allergen-specific immunotherapy

(2011) Cezmi A. Akdis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Expression and Function of C5a Receptor in a Fatal Anaphylaxis After Honey Bee Sting*

(2011) Klára Törő et al.   JOURNAL OF FORENSIC SCIENCES

Evaluation of Different Glycoforms of Honeybee Venom Major Allergen Phospholipase A2 (Api m 1) Produced in Insect Cells

(2011) Simon Blank et al.   PROTEIN AND PEPTIDE LETTERS

Quantification of melittin and apamin in bee venom lyophilized powder from Apis mellifera by liquid chromatography–diode array detector–tandem mass spectrometry

(2010) Jinhui Zhou et al.   ANALYTICAL BIOCHEMISTRY

Comparative genomic and phylogenetic analysis of vitellogenin and other large lipid transfer proteins in metazoans

(2010) Alexander Hayward et al.   FEBS LETTERS

Anaphylaxis

(2010) F. Estelle R. Simons   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Guidelines for the Diagnosis and Management of Food Allergy in the United States: Summary of the NIAID-Sponsored Expert Panel Report

(2010) Joshua A. Boyce et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Added value of IgE detection to rApi m 1 and rVes v 5 in patients with Hymenoptera venom allergy

(2010) Silke C. Hofmann et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Identification, Recombinant Expression, and Characterization of the 100 kDa High Molecular Weight Hymenoptera Venom Allergens Api m 5 and Ves v 3

(2010) S. Blank et al.   JOURNAL OF IMMUNOLOGY

Characterization of honeybee venom by MALDI-TOF and nanoESI-QqTOF mass spectrometry

(2010) Jan Matysiak et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Three-dimensional model of the honeybee venom allergen Api m 7: structural and functional insights

(2010) Dessislava Georgieva et al.   Molecular BioSystems

Africanized honey bee (Apis mellifera) venom profiling: Seasonal variation of melittin and phospholipase A2 levels

(2010) Rui S. Ferreira Junior et al.   TOXICON

Epidemiology of insect-venom anaphylaxis

(2009) Beatrice M Bilò et al.   Current Opinion in Allergy and Clinical Immunology

The safety of initiating Hymenoptera immunotherapy at 1 μg of venom extract

(2009) Areti Roumana et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Protein structure prediction on the Web: a case study using the Phyre server

(2009) Lawrence A Kelley et al.   Nature Protocols

Hymenoptera venom allergy: analysis of double positivity to honey bee andVespulavenom by estimation of IgE antibodies to species-specific major allergens Api m1 and Ves v5

(2008) U. R. Müller et al.   ALLERGY

Detection of honeybee venom in envenomed tissues by direct MALDI MSI

(2008) Simona Francese et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY