Papain Ameliorates Lipid Accumulation and Inflammation in High-Fat Diet-Induced Obesity Mice and 3T3-L1 Adipocytes via AMPK Activation

Liver governs adipose remodelling via extracellular vesicles in response to lipid overload

(2020) Yue Zhao et al.   Nature Communications

Anti-Adipogenic Effect of Neferine in 3T3-L1 Cells and Primary White Adipocytes

(2020) Miey Park et al.   Nutrients

Platycodon grandiflorum Extract Reduces High-Fat Diet-Induced Obesity Through Regulation of Adipogenesis and Lipogenesis Pathways in Mice

(2019) Kyung-A Hwang et al.   JOURNAL OF MEDICINAL FOOD

Nutraceutical Potential of Carica papaya in Metabolic Syndrome

(2019) Lidiani F. Santana et al.   Nutrients

Alleviating airway inflammation by inhibiting ERK-NF-κB signaling pathway by blocking Kv1.3 channels

(2018) Qian-Lan Zhou et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Papain Ameliorates the MPAs Formation-Mediated Activation of Monocytes by Inhibiting Cox-2 Expression via Regulating the MAPKs and PI3K/Akt Signal Pathway

(2018) Xianming Fei et al.   Biomed Research International

Natural anti-obesity agents and their therapeutic role in management of obesity: A future trend perspective

(2018) Sravani Karri et al.   BIOMEDICINE & PHARMACOTHERAPY

Tenebrio molitor Larvae Inhibit Adipogenesis through AMPK and MAPKs Signaling in 3T3-L1 Adipocytes and Obesity in High-Fat Diet-Induced Obese Mice

(2017) Minchul Seo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

AMPK and SIRT1 activation contribute to inhibition of neuroinflammation by thymoquinone in BV2 microglia

(2017) Ravikanth Velagapudi et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance

(2017) Daniel Garcia et al.   MOLECULAR CELL

In vitro efficacy of latex and purified papain from Carica papaya against Strongyloides venezuelensis eggs and larvae

(2017) Dayane Moraes et al.   REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO

FoxO1 antagonist suppresses autophagy and lipid droplet growth in adipocytes

(2016) Longhua Liu et al.   CELL CYCLE

Antibacterial activity of papain and bromelain on Alicyclobacillus spp.

(2016) Márcia Maria dos Anjos et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Quantitative analysis of rat adipose tissue cell recovery, and non-fat cell volume, in primary cell cultures

(2016) Floriana Rotondo et al.   PeerJ

The Roles of Adipokines, Proinflammatory Cytokines, and Adipose Tissue Macrophages in Obesity-Associated Insulin Resistance in Modest Obesity and Early Metabolic Dysfunction

(2016) Yea Eun Kang et al.   PLoS One

In vitro effects of fermented papaya (Carica papaya, L.) on platelets obtained from patients with type 2 diabetes

(2015) F. Raffaelli et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Antimicrobial activity of Eucalyptus globulus oil, xylitol and papain: a pilot study

(2015) Valéria de Siqueira Mota et al.   Revista da Escola de Enfermagem da USP

Effects of AMPK Activation on Insulin Sensitivity and Metabolism in Leptin-Deficientob/obMice

(2014) Robby Zachariah Tom et al.   DIABETES

AMPK activation: a therapeutic target for type 2 diabetes?

(2014) Asish Saha et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

Role of AMP-activated protein kinase in adipose tissue metabolism and inflammation

(2013) Silvia Bijland et al.   CLINICAL SCIENCE

AMPK Enhances Insulin-Stimulated GLUT4 Regulation via Lowering Membrane Cholesterol

(2012) Kirk M. Habegger et al.   ENDOCRINOLOGY

Anti-Obesity Drugs: A Review about Their Effects and Safety

(2012) Jun Goo Kang et al.   Diabetes & Metabolism Journal

Inflammatory Mechanisms in Obesity

(2011) Margaret F. Gregor et al.   Annual Review of Immunology

Regulation of AMP-activated protein kinase by LKB1 and CaMKK in adipocytes

(2011) Amélie Gormand et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Macrophage α1 AMP-activated Protein Kinase (α1AMPK) Antagonizes Fatty Acid-induced Inflammation through SIRT1

(2010) Zhenggang Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antiinflammatory activity of the methanolic extract of the seeds of Carica papaya in experimental animals

(2010) LU Amazu et al.   Asian Pacific Journal of Tropical Medicine

The incidence of co-morbidities related to obesity and overweight: A systematic review and meta-analysis

(2009) Daphne P Guh et al.   BMC PUBLIC HEALTH

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE

The Perfect Storm: Obesity, Adipocyte Dysfunction, and Metabolic Consequences

(2008) S. de Ferranti et al.   CLINICAL CHEMISTRY

SIRT1 Modulation of the Acetylation Status, Cytosolic Localization, and Activity of LKB1

(2008) Fan Lan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY