Fucoidan induces ROS-dependent epigenetic modulation in cervical cancer HeLa cell

SAHA and EGCG Promote Apoptosis in Triple-negative Breast Cancer Cells, Possibly Through the Modulation of cIAP2

(2020) KAYLA L. STEED et al.   ANTICANCER RESEARCH

A review on fucoidan antitumor strategies: From a biological active agent to a structural component of fucoidan-based systems

(2020) Catarina Oliveira et al.   CARBOHYDRATE POLYMERS

Targeting COVID-19 in Parkinson’s patients: Drugs repurposed.

(2020) Firoz Anwar et al.   CURRENT MEDICINAL CHEMISTRY

Exploring the p53 connection of cervical cancer pathogenesis involving north-east Indian patients

(2020) Mohammad Aasif Khan et al.   PLoS One

Design, Synthesis, Anti-Proliferative Evaluation and Cell Cycle Analysis of Hybrid 2-Quinolones A New Class of Hybrid 2-Quinolone Derivatives As Anticancer Agents

(2019) Heba Abd Elhady Mohamed et al.   Anti-Cancer Agents in Medicinal Chemistry

Therapeutic Effects of Fucoidan: A Review on Recent Studies

(2019) Sibusiso Luthuli et al.   Marine Drugs

N-Acetyl-L-cysteine Protects Human Retinal Pigment Epithelial Cells from Oxidative Damage: Implications for Age-Related Macular Degeneration

(2019) Marcia R. Terluk et al.   Oxidative Medicine and Cellular Longevity

20(S)-Ginsenoside Rg3 Promotes HeLa Cell Apoptosis by Regulating Autophagy

(2019) Bian et al.   MOLECULES

LC–MS and docking profiling reveals potential difference between the pure and crude fucoidan metabolites

(2019) Saad Mustafa et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

admetSAR 2.0: web-service for prediction and optimization of chemical ADMET properties

(2018) Hongbin Yang et al.   BIOINFORMATICS

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Baicalein induces apoptosis and autophagy of breast cancer cells via inhibiting PI3K/AKT pathway in vivo and vitro

(2018) Wanjun Yan et al.   Drug Design Development and Therapy

Histone Deacetylase Inhibitor SAHA as Potential Targeted Therapy Agent for Larynx Cancer Cells

(2017) Aneta Grabarska et al.   Journal of Cancer

vNN Web Server for ADMET Predictions

(2017) Patric Schyman et al.   Frontiers in Pharmacology

A combined approach against tumorigenesis using glucose deprivation and mitochondrial complex 1 inhibition by rotenone

(2016) Nupur Rani Agarwal et al.   CELL BIOLOGY INTERNATIONAL

Pathogenic Network Analysis Predicts Candidate Genes for Cervical Cancer

(2016) Yun-Xia Zhang et al.   Computational and Mathematical Methods in Medicine

Updates on Managing Type 2 Diabetes Mellitus with Natural Products: Towards Antidiabetic Drug Development

(2016) Fahmida Alam et al.   CURRENT MEDICINAL CHEMISTRY

Mitochondria are required for pro‐ageing features of the senescent phenotype

(2016) Clara Correia‐Melo et al.   EMBO JOURNAL

In vitro and in vivo hypoglycemic effects of brown algal fucoidans

(2016) Xindi Shan et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Physicochemical and Biological Characterization of Fucoidan from Fucus vesiculosus Purified by Dye Affinity Chromatography

(2016) Ahmed Zayed et al.   Marine Drugs

ROS, Cell Senescence, and Novel Molecular Mechanisms in Aging and Age-Related Diseases

(2016) Pierpaola Davalli et al.   Oxidative Medicine and Cellular Longevity

Histone Acetylation and Its Modifiers in the Pathogenesis of Diabetic Nephropathy

(2016) Xiaoxia Li et al.   Journal of Diabetes Research

Antidepressant indatraline induces autophagy and inhibits restenosis via suppression of mTOR/S6 kinase signaling pathway

(2016) Yoon Sun Cho et al.   Scientific Reports

Mitochondria in health, aging and diseases: the epigenetic perspective

(2015) Patrizia D’Aquila et al.   BIOGERONTOLOGY

Histone deacetylases 1 and 2 regulate DNA replication and DNA repair: potential targets for genome stability-mechanism-based therapeutics for a subset of cancers

(2015) Srividya Bhaskara   CELL CYCLE

Selective Inhibition of HDAC1 and HDAC2 as a Potential Therapeutic Option for B-ALL

(2015) M. C. Stubbs et al.   CLINICAL CANCER RESEARCH

Quantification of proteins by flow cytometry: Quantification of human hepatic transporter P-gp and OATP1B1 using flow cytometry and mass spectrometry

(2015) Karen Hogg et al.   METHODS

In silico identification of 2-oxo-1,3-thiazolidine derivatives as novel inhibitors candidate of class II histone deacetylase (HDAC) in cervical cancer treatment

(2015) Usman S.F. Tambunan et al.   Arabian Journal of Chemistry

Oxidative stress triggered by naturally occurring flavone apigenin results in senescence and chemotherapeutic effect in human colorectal cancer cells

(2015) Kacoli Banerjee et al.   Redox Biology

Mitochondrial effectors of cellular senescence: beyond the free radical theory of aging

(2014) Dorian V. Ziegler et al.   AGING CELL

Oxidative stress and autophagy: the clash between damage and metabolic needs

(2014) G Filomeni et al.   CELL DEATH AND DIFFERENTIATION

The effects of fucodian on senescence are controlled by the p16INK4a-pRb and p14Arf-p53 pathways in hepatocellular carcinoma and hepatic cell lines

(2014) EUN-YOUNG MIN et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Suberoylanilide hydroxamic acid-induced HeLa cell death is closely correlated with oxidative stress and thioredoxin 1 levels

(2014) BO RA YOU et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

New Nucleophilic Mechanisms of Ros-Dependent Epigenetic Modifications: Comparison of Aging and Cancer

(2014) Igor Afanas’ev   Aging and Disease

Autophagic Vacuolation Induced by Excess ROS Generation in HABP1/p32/gC1qR Overexpressing Fibroblasts and Its Reversal by Polymeric Hyaluronan

(2013) Paramita Saha et al.   PLoS One

Molecular Mechanism of SAHA on Regulation of Autophagic Cell Death in Tamoxifen-Resistant MCF-7 Breast Cancer Cells

(2012) Young Ju Lee et al.   International Journal of Medical Sciences

Overexpression of Hyaluronan-binding Protein 1 (HABP1/p32/gC1qR) in HepG2 Cells Leads to Increased Hyaluronan Synthesis and Cell Proliferation by Up-regulation of Cyclin D1 in AKT-dependent Pathway

(2012) Rachna Kaul et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone deacetylases and cancer

(2012) Bruna Barneda-Zahonero et al.   Molecular Oncology

Anticancer Properties and Mechanisms of Fucoidan on Mouse Breast Cancer In Vitro and In Vivo

(2012) Meilan Xue et al.   PLoS One

Fucoidan from Seaweed Fucus vesiculosus Inhibits Migration and Invasion of Human Lung Cancer Cell via PI3K-Akt-mTOR Pathways

(2012) Hyunkyoung Lee et al.   PLoS One

All-trans retinoic acid induces cellular senescence via upregulation of p16, p21, and p27

(2011) Sun-Hye Park et al.   CANCER LETTERS

Hyaluronan-binding protein 1 (HABP1/p32/gC1qR) induces melanoma cell migration and tumor growth by NF-kappa B dependent MMP-2 activation through integrin αvβ3 interaction

(2011) Mansi Prakash et al.   CELLULAR SIGNALLING

Anti-inflammatory effects of fucoidan through inhibition of NF-κB, MAPK and Akt activation in lipopolysaccharide-induced BV2 microglia cells

(2011) Hye Young Park et al.   FOOD AND CHEMICAL TOXICOLOGY

Tumor suppressor genes and ROS: complex networks of interactions

(2011) Beyza Vurusaner et al.   FREE RADICAL BIOLOGY AND MEDICINE

Pro-oxidant and antioxidant effects of N-acetylcysteine regulate doxorubicin-induced NF-kappa B activity in leukemic cells

(2011) Nnenna Adimora Finn et al.   Molecular BioSystems

Regulation of reactive oxygen species generation in cell signaling

(2011) Yun Soo Bae et al.   MOLECULES AND CELLS

p16Ink4a overexpression in cancer: a tumor suppressor gene associated with senescence and high-grade tumors

(2011) C Romagosa et al.   ONCOGENE

Regulating the Regulators: The Post-Translational Code of Class I HDAC1 and HDAC2

(2010) Chiara V. Segré et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

Characterization of the HDAC1 Complex That Regulates the Sensitivity of Cancer Cells to Oxidative Stress

(2009) T. Kato et al.   CANCER RESEARCH

Histone deacetylase inhibitor (SAHA) and repression of EZH2 synergistically inhibit proliferation of gallbladder carcinoma

(2009) Junpei Yamaguchi et al.   CANCER SCIENCE

Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes

(2009) Zhibin Wang et al.   CELL

Combination of Proteasome and HDAC Inhibitors for Uterine Cervical Cancer Treatment

(2009) Z. Lin et al.   CLINICAL CANCER RESEARCH

Global networks of functional coupling in eukaryotes from comprehensive data integration

(2009) A. Alexeyenko et al.   GENOME RESEARCH

Inhibition of histone deacetylase1 induces autophagy

(2008) Meeyeon Oh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS