The many ways astroglial connexins regulate neurotransmission and behavior

Stress gates an astrocytic energy reservoir to impair synaptic plasticity

(2020) Ciaran Murphy-Royal et al.   Nature Communications

Connexin43 Region 266–283, via Src Inhibition, Reduces Neural Progenitor Cell Proliferation Promoted by EGF and FGF-2 and Increases Astrocytic Differentiation

(2020) Rocío Talaverón et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Astrocyte function from information processing to cognition and cognitive impairment

(2019) Mirko Santello et al.   NATURE NEUROSCIENCE

Astroglial Cx30 sustains neuronal population bursts independently of gap-junction mediated biochemical coupling

(2019) Ulrike Pannasch et al.   GLIA

Transcriptional regulation of the Glutamate/GABA/Glutamine cycle in adult glia controls motor activity and seizures in Drosophila

(2019) David Mazaud et al.   JOURNAL OF NEUROSCIENCE

Connexin30 and Connexin43 show a time-of-day dependent expression in the mouse suprachiasmatic nucleus and modulate rhythmic locomotor activity in the context of chronodisruption

(2019) Amira A. H. Ali et al.   Cell Communication and Signaling

Neuronal Activity Drives Astroglial Connexin 30 in Perisynaptic Processes and Shapes Its Functions

(2019) Grégory Ghézali et al.   CEREBRAL CORTEX

Connexin 30 controls astroglial polarization during postnatal brain development

(2018) Grégory Ghézali et al.   DEVELOPMENT

Circadian coordination of ATP release in the urothelium via connexin43 hemichannels

(2018) Atsushi Sengiku et al.   Scientific Reports

Syncytial isopotentiality: A system-wide electrical feature of astrocytic networks in the brain

(2018) Conrad M. Kiyoshi et al.   GLIA

Diversity and properties of connexin gap junction channels

(2018) Mindaugas Račkauskas et al.   Medicina-Lithuania

Versatile control of synaptic circuits by astrocytes: where, when and how?

(2018) Glenn Dallérac et al.   NATURE REVIEWS NEUROSCIENCE

Glia as architects of central nervous system formation and function

(2018) Nicola J. Allen et al.   SCIENCE

Functional rhythmogenic domains defined by astrocytic networks in the trigeminal main sensory nucleus

(2017) Steven Condamine et al.   GLIA

Molecular and Functional Properties of Regional Astrocytes in the Adult Brain

(2017) Lydie Morel et al.   JOURNAL OF NEUROSCIENCE

Contribution of Astroglial Cx43 Hemichannels to the Modulation of Glutamatergic Currents by D-Serine in the Mouse Prefrontal Cortex

(2017) Claire Meunier et al.   JOURNAL OF NEUROSCIENCE

Astrocytic gap junction blockade markedly increases extracellular potassium without causing seizures in the mouse neocortex

(2017) Paolo Bazzigaluppi et al.   NEUROBIOLOGY OF DISEASE

Modulation of Tonic GABA Currents by Anion Channel and Connexin Hemichannel Antagonists

(2017) Christopher B. Ransom et al.   NEUROCHEMICAL RESEARCH

Inhibition of Gap Junction Elevates Glutamate Uptake in Cultured Astrocytes

(2017) Katsura Takano et al.   NEUROCHEMICAL RESEARCH

Connexin 43-Mediated Astroglial Metabolic Networks Contribute to the Regulation of the Sleep-Wake Cycle

(2017) Jerome Clasadonte et al.   NEURON

Cell Biology of Astrocyte-Synapse Interactions

(2017) Nicola J. Allen et al.   NEURON

Astrocytic modulation of neuronal excitability through K + spatial buffering

(2017) Alba Bellot-Saez et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Astrocytic control of synaptic function

(2017) Thomas Papouin et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

A structural and functional comparison of gap junction channels composed of connexins and innexins

(2016) I. Martha Skerrett et al.   Developmental Neurobiology

Rapid sodium signaling couples glutamate uptake to breakdown of ATP in perivascular astrocyte endfeet

(2016) Julia Langer et al.   GLIA

Methamphetamine compromises gap junctional communication in astrocytes and neurons

(2016) Paul Castellano et al.   JOURNAL OF NEUROCHEMISTRY

Evidence for alterations of the glial syncytial function in major depressive disorder

(2016) Adriana Medina et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Functional diversity of astrocytes in neural circuit regulation

(2016) Lucile Ben Haim et al.   NATURE REVIEWS NEUROSCIENCE

Astrocytes as new targets to improve cognitive functions

(2016) Glenn Dallérac et al.   PROGRESS IN NEUROBIOLOGY

Astroglial networks promote neuronal coordination

(2016) Oana Chever et al.   Science Signaling

Antidepressants Impact Connexin 43 Channel Functions in Astrocytes

(2016) Tiffany Jeanson et al.   Frontiers in Cellular Neuroscience

Inhibition of Connexin43 Hemichannels Impairs Spatial Short-Term Memory without Affecting Spatial Working Memory

(2016) Laura Walrave et al.   Frontiers in Cellular Neuroscience

Astroglial networks promote neuronal coordination

(2016) Oana Chever et al.   Science Signaling

Superresolution Imaging of Aquaporin-4 Cluster Size in Antibody-Stained Paraffin Brain Sections

(2015) Alex J. Smith et al.   BIOPHYSICAL JOURNAL

General anesthetics have differential inhibitory effects on gap junction channels and hemichannels in astrocytes and neurons

(2015) Xinhe Liu et al.   GLIA

Gap junction coupling confers isopotentiality on astrocyte syncytium

(2015) Baofeng Ma et al.   GLIA

Activated microglia impairs neuroglial interaction by opening Cx43 hemichannels in hippocampal astrocytes

(2015) Verónica Abudara et al.   GLIA

Astroglial Connexin 43 Hemichannels Modulate Olfactory Bulb Slow Oscillations

(2015) L. Roux et al.   JOURNAL OF NEUROSCIENCE

An astrocyte-dependent mechanism for neuronal rhythmogenesis

(2015) Philippe Morquette et al.   NATURE NEUROSCIENCE

Proximity of excitatory synapses and astroglial gap junctions in layer IV of the mouse barrel cortex

(2015) C. Genoud et al.   NEUROSCIENCE

Ion Homeostasis in Rhythmogenesis: The Interplay Between Neurons and Astroglia

(2015) Aklesso Kadala et al.   PHYSIOLOGY

The Blood–Brain Barrier

(2015) Richard Daneman et al.   Cold Spring Harbor Perspectives in Biology

Astrocytes Control Synapse Formation, Function, and Elimination

(2015) Won-Suk Chung et al.   Cold Spring Harbor Perspectives in Biology

Risk Factors for Anxiety in Major Depressive Disorder Patients

(2015) Li-Min Xin et al.   Clinical Psychopharmacology and Neuroscience

Amitriptyline up-regulates connexin43-gap junction in rat cultured cortical astrocytes via activation of the p38 and c-Fos/AP-1 signalling pathway

(2014) N Morioka et al.   BRITISH JOURNAL OF PHARMACOLOGY

Connexin hemichannel and pannexin channel electrophysiology: How do they differ?

(2014) Dakshesh Patel et al.   FEBS LETTERS

Distinct permeation profiles of the connexin 30 and 43 hemichannels

(2014) Daniel Bloch Hansen et al.   FEBS LETTERS

Disruption of dopaminergic transmission remodels tripartite synapse morphology and astrocytic calcium activity within substantia nigra pars reticulata

(2014) Anthony Bosson et al.   GLIA

Activation, Permeability, and Inhibition of Astrocytic and Neuronal Large Pore (Hemi)channels

(2014) Daniel Bloch Hansen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Astroglial Connexin43 Hemichannels Tune Basal Excitatory Synaptic Transmission

(2014) O. Chever et al.   JOURNAL OF NEUROSCIENCE

Reduced connexin 43 immunolabeling in the orbitofrontal cortex in alcohol dependence and depression

(2014) José Javier Miguel-Hidalgo et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Connexin 30 sets synaptic strength by controlling astroglial synapse invasion

(2014) Ulrike Pannasch et al.   NATURE NEUROSCIENCE

A Local Glutamate-Glutamine Cycle Sustains Synaptic Excitatory Transmitter Release

(2014) Hiroaki Tani et al.   NEURON

Astroglial connexin 43 sustains glutamatergic synaptic efficacy

(2014) O. Chever et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Connexons and pannexons: newcomers in neurophysiology

(2014) Giselle Cheung et al.   Frontiers in Cellular Neuroscience

Cl−homeodynamics in gap junction-coupled astrocytic networks on activation of GABAergic synapses

(2013) Kiyoshi Egawa et al.   JOURNAL OF PHYSIOLOGY-LONDON

Emerging roles of astrocytes in neural circuit development

(2013) Laura E. Clarke et al.   NATURE REVIEWS NEUROSCIENCE

Activity-Dependent Changes in Extracellular Ca2+ and K+ Reveal Pacemakers in the Spinal Locomotor-Related Network

(2013) Frédéric Brocard et al.   NEURON

Regulation of connexin hemichannel activity by membrane potential and the extracellular calcium in health and disease

(2013) Ilaria Fasciani et al.   NEUROPHARMACOLOGY

The psychostimulant modafinil enhances gap junctional communication in cortical astrocytes

(2013) Xinhe Liu et al.   NEUROPHARMACOLOGY

Connexin targeting peptides as inhibitors of voltage- and intracellular Ca2+-triggered Cx43 hemichannel opening

(2013) Nan Wang et al.   NEUROPHARMACOLOGY

Connexin43 Hemichannel-Mediated Regulation of Connexin43

(2013) Kai Li et al.   PLoS One

Emerging role for astroglial networks in information processing: from synapse to behavior

(2013) Ulrike Pannasch et al.   TRENDS IN NEUROSCIENCES

Selective inhibition of Cx43 hemichannels by Gap19 and its impact on myocardial ischemia/reperfusion injury

(2012) Nan Wang et al.   BASIC RESEARCH IN CARDIOLOGY

DIAGNOSTIC OVERLAP OF GENERALIZED ANXIETY DISORDER AND MAJOR DEPRESSIVE DISORDER IN A PRIMARY CARE SAMPLE

(2012) Tomislav D. Zbozinek et al.   DEPRESSION AND ANXIETY

Release of gliotransmitters through astroglial connexin 43 hemichannels is necessary for fear memory consolidation in the basolateral amygdala

(2012) Jimmy Stehberg et al.   FASEB JOURNAL

Control of Sleep and Wakefulness

(2012) Ritchie E. Brown et al.   PHYSIOLOGICAL REVIEWS

Extracellular Ca2+ Acts as a Mediator of Communication from Neurons to Glia

(2012) A. Torres et al.   Science Signaling

Dysfunction of Astrocyte Connexins 30 and 43 in Dorsal Lateral Prefrontal Cortex of Suicide Completers

(2011) Carl Ernst et al.   BIOLOGICAL PSYCHIATRY

Network bursts in hippocampal microcultures are terminated by exhaustion of vesicle pools

(2011) Dror Cohen et al.   JOURNAL OF NEUROPHYSIOLOGY

Gap Junction Dysfunction in the Prefrontal Cortex Induces Depressive-Like Behaviors in Rats

(2011) Jian-Dong Sun et al.   NEUROPSYCHOPHARMACOLOGY

Connexin-deficiency affects expression levels of glial glutamate transporters within the cerebrum

(2011) Tina Unger et al.   NEUROSCIENCE LETTERS

Astroglial networks scale synaptic activity and plasticity

(2011) U. Pannasch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasticity of astroglial networks in olfactory glomeruli

(2011) L. Roux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Electrical Synapses Control Hippocampal Contributions to Fear Learning and Memory

(2011) S. Bissiere et al.   SCIENCE

The Carboxyl-terminal Domain of Connexin43 Is a Negative Modulator of Neuronal Differentiation

(2010) Marcelo F. Santiago et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Connexin 43 Mediates the Tangential to Radial Migratory Switch in Ventrally Derived Cortical Interneurons

(2010) L. A. B. Elias et al.   JOURNAL OF NEUROSCIENCE

Altered expression of glutamate signaling, growth factor and glia genes in the locus coeruleus of patients with major depression

(2010) R Bernard et al.   MOLECULAR PSYCHIATRY

Astroglial networks: a step further in neuroglial and gliovascular interactions

(2010) Christian Giaume et al.   NATURE REVIEWS NEUROSCIENCE

Electrical coupling of astrocytes in rat hippocampal slices under physiological and simulated ischemic conditions

(2009) Guangjin Xu et al.   GLIA

Selective astrocytic gap junctional trafficking of molecules involved in the glycolytic pathway: impact on cellular brain imaging

(2009) Gautam K. Gandhi et al.   JOURNAL OF NEUROCHEMISTRY

Involvement of the Cytoplasmic C-Terminal Domain of Connexin43 in Neuronal Migration

(2009) C. Cina et al.   JOURNAL OF NEUROSCIENCE

Deletion of Astrocyte Connexins 43 and 30 Leads to a Dysmyelinating Phenotype and Hippocampal CA1 Vacuolation

(2009) S. E. Lutz et al.   JOURNAL OF NEUROSCIENCE

Astrocytic Modulation of Sleep Homeostasis and Cognitive Consequences of Sleep Loss

(2009) Michael M. Halassa et al.   NEURON

Cadmium and cellular signaling cascades: To be or not to be?

(2009) Frank Thévenod   TOXICOLOGY AND APPLIED PHARMACOLOGY

Similar Transcriptomic Alterations in Cx43 Knockdown and Knockout Astrocytes

(2008) Dumitru A. Iacobas et al.   CELL COMMUNICATION AND ADHESION

Connexin 43 mimetic peptides inhibit spontaneous epileptiform activity in organotypic hippocampal slice cultures

(2008) Marina Samoilova et al.   EXPERIMENTAL NEUROLOGY

Adhesive properties of connexin hemichannels

(2008) M. L. Cotrina et al.   GLIA

Connexin 43 Hemichannels Are Permeable to ATP

(2008) J. Kang et al.   JOURNAL OF NEUROSCIENCE

Gap Junction-Mediated Astrocytic Networks in the Mouse Barrel Cortex

(2008) V. Houades et al.   JOURNAL OF NEUROSCIENCE

Astroglial Metabolic Networks Sustain Hippocampal Synaptic Transmission

(2008) N. Rouach et al.   SCIENCE

Gap junctions: multifaceted regulators of embryonic cortical development

(2008) Laura A.B. Elias et al.   TRENDS IN NEUROSCIENCES

Lack of connexin43-mediated Bergmann glial gap junctional coupling does not affect cerebellar long-term depression, motor coordination, or eyeblink conditioning

(2008) Mika Tanaka   Frontiers in Behavioral Neuroscience

Modulation of astrocyte P2Y1receptors by the carboxyl terminal domain of the gap junction protein Cx43

(2007) Eliana Scemes   GLIA