Connexin43 Region 266–283, via Src Inhibition, Reduces Neural Progenitor Cell Proliferation Promoted by EGF and FGF-2 and Increases Astrocytic Differentiation

Glial connexins and pannexins in the healthy and diseased brain

(2020) Christian BA Giaume et al.   PHYSIOLOGICAL REVIEWS

SRC Kinase in Glioblastoma: News from an Old Acquaintance

(2020) Claudia Cirotti et al.   Cancers

Neural Stem Cells of the Subventricular Zone as the Origin of Human Glioblastoma Stem Cells. Therapeutic Implications

(2019) Esperanza R. Matarredona et al.   Frontiers in Oncology

Connexin43 peptide, TAT-Cx43266–283, selectively targets glioma cells, impairs malignant growth, and enhances survival in mouse models in vivo

(2019) Myriam Jaraíz-Rodríguez et al.   NEURO-ONCOLOGY

The connexin 43 C-terminus: A tail of many tales

(2018) Edward Leithe et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Connexin43 Carboxyl-Terminal Domain Directly Interacts with β-Catenin

(2018) Gaelle Spagnol et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Human glioblastoma arises from subventricular zone cells with low-level driver mutations

(2018) Joo Ho Lee et al.   NATURE

A c-Src Inhibitor Peptide Based on Connexin43 Exerts Neuroprotective Effects through the Inhibition of Glial Hemichannel Activity

(2017) Ester Gangoso et al.   Frontiers in Molecular Neuroscience

A Short Region of Connexin43 Reduces Human Glioma Stem Cell Migration, Invasion, and Survival through Src, PTEN, and FAK

(2017) Myriam Jaraíz-Rodríguez et al.   Stem Cell Reports

Inhibition of N1-Src kinase by a specific SH3 peptide ligand reveals a role for N1-Src in neurite elongation by L1-CAM

(2017) Sarah Keenan et al.   Scientific Reports

Connexin43 recruits PTEN and Csk to inhibit c-Src activity in glioma cells and astrocytes

(2016) Ana González-Sánchez et al.   Oncotarget

Connexin and pannexin signaling pathways, an architectural blueprint for CNS physiology and pathology?

(2015) Elke Decrock et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Dasatinib in recurrent glioblastoma: failure as a teacher

(2015) David Schiff et al.   NEURO-ONCOLOGY

Adult neural precursor cells form connexin-dependent networks that improve their survival

(2015) Ajaya Ravella et al.   NEUROREPORT

Neural progenitor cells isolated from the subventricular zone present hemichannel activity and form functional gap junctions with glial cells

(2015) Rocío Talaverón et al.   Frontiers in Cellular Neuroscience

PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype

(2015) Shunlei Duan et al.   Nature Communications

The role of Src family kinases in growth and migration of glioma stem cells

(2014) XIAOSI HAN et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Cross-regulation of Connexin43 and β-catenin influences differentiation of human neural progenitor cells

(2014) F Rinaldi et al.   Cell Death & Disease

A cell-penetrating peptide based on the interaction between c-Src and connexin43 reverses glioma stem cell phenotype

(2014) E Gangoso et al.   Cell Death & Disease

Brain stem cells as the cell of origin in glioma

(2014) Aram S Modrek   World Journal of Stem Cells

Neural Progenitor Cell Implants Modulate Vascular Endothelial Growth Factor and Brain-Derived Neurotrophic Factor Expression in Rat Axotomized Neurons

(2013) Rocío Talaverón et al.   PLoS One

 -Catenin signaling specifies progenitor cell identity in parallel with Shh signaling in the developing mammalian thalamus

(2012) K. K. Bluske et al.   DEVELOPMENT

EGFR/Src/Akt signaling modulates Sox2 expression and self-renewal of stem-like side-population cells in non-small cell lung cancer

(2012) Sandeep Singh et al.   Molecular Cancer

Src family kinases mediate epidermal growth factor receptor signaling from lipid rafts in breast cancer cells

(2011) Mary E. Irwin et al.   CANCER BIOLOGY & THERAPY

Gap junction-mediated calcium waves define communication networks among murine postnatal neural progenitor cells

(2011) Benjamin Lacar et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome

(2011) Solveig Sirnes et al.   INTERNATIONAL JOURNAL OF CANCER

The Carboxyl-terminal Domain of Connexin43 Is a Negative Modulator of Neuronal Differentiation

(2010) Marcelo F. Santiago et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Connexin43 inhibits the oncogenic activity of c-Src in C6 glioma cells

(2010) S Herrero-González et al.   ONCOGENE

Expression of Mutant p53 Proteins Implicates a Lineage Relationship between Neural Stem Cells and Malignant Astrocytic Glioma in a Murine Model

(2009) Yuan Wang et al.   CANCER CELL

Malignant Astrocytomas Originate from Neural Stem/Progenitor Cells in a Somatic Tumor Suppressor Mouse Model

(2009) Sheila Alcantara Llaguno et al.   CANCER CELL

Involvement of the Cytoplasmic C-Terminal Domain of Connexin43 in Neuronal Migration

(2009) C. Cina et al.   JOURNAL OF NEUROSCIENCE

Effects of dasatinib on EphA2 receptor tyrosine kinase activity and downstream signalling in pancreatic cancer

(2008) Q Chang et al.   BRITISH JOURNAL OF CANCER

Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy

(2008) Jinyan Du et al.   NATURE BIOTECHNOLOGY