Kaempferol alleviates corneal transplantation rejection by inhibiting NLRP3 inflammasome activation and macrophage M1 polarization via promoting autophagy

NLRP3 inflammasome mediates M1 macrophage polarization and IL‐1β production in inflammatory root resorption

(2020) Jie Zhang et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Select autophagy genes maintain quiescence of tissue-resident macrophages and increase susceptibility to Listeria monocytogenes

(2020) Ya-Ting Wang et al.   Nature Microbiology

Gut microbial metabolite trimethylamine N-oxide aggravates GVHD by inducing M1 macrophage polarization in mice

(2020) Kunpeng Wu et al.   BLOOD

BET protein inhibition prolongs cardiac transplant survival via enhanced yocardial autophagy

(2020) Juntao Chen et al.   TRANSPLANTATION

Corneal graft failure: an update

(2020) Jorge L Alio et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Targeting Autophagy in Breast Cancer

(2020) Stefania Cocco et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Corneal Transplantation after Failed Grafts: Options and Outcomes

(2020) Jorge L. Alió del Barrio et al.   SURVEY OF OPHTHALMOLOGY

Lipoxin A4 Inhibits NLRP3 Inflammasome Activation in Rats With Non-compressive Disc Herniation Through the JNK1/Beclin-1/PI3KC3 Pathway

(2020) Jin Jin et al.   Frontiers in Neuroscience

Human Autoinflammatory Diseases Mediated by NLRP3-, Pyrin-, NLRP1-, and NLRC4-Inflammasome Dysregulation Updates on Diagnosis, Treatment, and the Respective Roles of IL-1 and IL-18

(2020) Sara Alehashemi et al.   Frontiers in Immunology

Extracellular SQSTM1 as an inflammatory mediator

(2020) Borong Zou et al.   Autophagy

Anti-glioblastoma Activity of Kaempferol via Programmed Cell Death Induction: Involvement of Autophagy and Pyroptosis

(2020) Suqin Chen et al.   Frontiers in Bioengineering and Biotechnology

Implications of macrophage polarization in corneal transplantation rejection

(2020) Huiwen Tian et al.   TRANSPLANT IMMUNOLOGY

Modulation of Autophagy for Controlling Immunity

(2019) Young Jin Jang et al.   Cells

Acetylation of BmAtg8 inhibits starvation-induced autophagy initiation

(2019) Shengjie Xue et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

M1 and M2 macrophage polarization and potentially therapeutic naturally occurring compounds

(2019) Youhan Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Kaempferol: A Key Emphasis to Its Anticancer Potential

(2019) Muhammad Imran et al.   MOLECULES

Mitochondrial ROS-induced lysosomal dysfunction impairs autophagic flux and contributes to M1 macrophage polarization in a diabetic condition

(2019) Yujia Yuan et al.   CLINICAL SCIENCE

High-Risk Corneal Transplantation

(2019) W. John Armitage et al.   TRANSPLANTATION

Accelerated and Severe Lupus Nephritis Benefits From M1, an Active Metabolite of Ginsenoside, by Regulating NLRP3 Inflammasome and T Cell Functions in Mice

(2019) Tsai-Jung Lin et al.   Frontiers in Immunology

The Osteoprotective Effects Of Kaempferol: The Evidence From In Vivo And In Vitro Studies

(2019) Sok Kuan Wong et al.   Drug Design Development and Therapy

Targeting NLRP3 Inflammasome Activation in Severe Asthma

(2019) Efthymia Theofani et al.   Journal of Clinical Medicine

Meisoindigo Protects Against Focal Cerebral Ischemia-Reperfusion Injury by Inhibiting NLRP3 Inflammasome Activation and Regulating Microglia/Macrophage Polarization via TLR4/NF-κB Signaling Pathway

(2019) Yingze Ye et al.   Frontiers in Cellular Neuroscience

Macrophages: Their role, activation and polarization in pulmonary diseases

(2018) Shweta Arora et al.   IMMUNOBIOLOGY

Kaempferol alleviates palmitic acid-induced lipid stores, endoplasmic reticulum stress and pancreatic β-cell dysfunction through AMPK/mTOR-mediated lipophagy

(2018) Ritu Varshney et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Chemopreventive Effects of Phytochemicals and Medicines on M1/M2 Polarized Macrophage Role in Inflammation-Related Diseases

(2018) Yen-Chun Koh et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Kaempferol induces autophagic cell death via IRE1-JNK-CHOP pathway and inhibition of G9a in gastric cancer cells

(2018) Tae Woo Kim et al.   Cell Death & Disease

Chemo-preventive and therapeutic effect of the dietary flavonoid kaempferol: A comprehensive review

(2018) Muhammad Imran et al.   PHYTOTHERAPY RESEARCH

Autophagy and its role in gastric cancer

(2018) Yijing Cao et al.   CLINICA CHIMICA ACTA

Inflammasomes and IL-1 biology in the pathogenesis of allograft dysfunction

(2017) S. Samuel Weigt et al.   JOURNAL OF CLINICAL INVESTIGATION

Management of high-risk corneal transplantation

(2017) Antonio Di Zazzo et al.   SURVEY OF OPHTHALMOLOGY

Kaempferol Promotes Transplant Tolerance by Sustaining CD4+FoxP3+ Regulatory T Cells in the Presence of Calcineurin Inhibitor

(2015) Y. Q. Zeng et al.   AMERICAN JOURNAL OF TRANSPLANTATION

WIPI2 Links LC3 Conjugation with PI3P, Autophagosome Formation, and Pathogen Clearance by Recruiting Atg12–5-16L1

(2014) Hannah C. Dooley et al.   MOLECULAR CELL

Cell plasticity in wound healing: paracrine factors of M1/ M2 polarized macrophages influence the phenotypical state of dermal fibroblasts

(2013) Diana TA Ploeger et al.   Cell Communication and Signaling

The Nlrp3 inflammasome regulates acute graft-versus-host disease

(2013) Dragana Jankovic et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Review on the Dietary Flavonoid Kaempferol

(2011) J. M. Calderon-Montano et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE