The Pivotal Link Between ACE2 Deficiency and SARS-CoV-2 Infection: One Year Later

Kinins and Chymase: The Forgotten Components of the Renin angiotensin system and their implications in COVID-19 Disease

(2021) Zaid Abassi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Soluble ACE2 as a potential therapy for COVID-19

(2021) Sudarshan Krishnamurthy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Covid-19: European countries suspend use of Oxford-AstraZeneca vaccine after reports of blood clots

(2021) Jacqui Wise   BMJ-British Medical Journal

ACE-2 down-regulation may act as a transient molecular disease causing RAAS dysregulation and tissue damage in the microcirculatory environment among COVID-19 patients

(2021) Simone Gusmão Ramos et al.   AMERICAN JOURNAL OF PATHOLOGY

SARS-CoV-2 vaccines: Lights and shadows

(2021) Fabio Angeli et al.   European Journal of Internal Medicine

Joint effect of heart failure and coronary artery disease on the risk of death during hospitalization for COVID-19

(2021) Fabio Angeli et al.   European Journal of Internal Medicine

Thrombosis and Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination

(2021) Nina H. Schultz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination

(2021) Andreas Greinacher et al.   NEW ENGLAND JOURNAL OF MEDICINE

Association Between Renin-Angiotensin-Aldosterone System Inhibitors and Clinical Outcomes in Patients With COVID-19

(2021) Ranu Baral et al.   JAMA Network Open

Ageing, ACE2 deficiency and bad outcome in COVID-19

(2021) Fabio Angeli et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Blood pressure increase after Pfizer/BioNTech SARS-CoV-2 vaccine

(2021) Martina Zappa et al.   European Journal of Internal Medicine

SARS-CoV-2 infection and ACE2 inhibition

(2021) Fabio Angeli et al.   JOURNAL OF HYPERTENSION

Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target

(2020) Haibo Zhang et al.   INTENSIVE CARE MEDICINE

Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury

(2020) Yingxia Liu et al.   Science China-Life Sciences

Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study

(2020) Xiaobo Yang et al.   Lancet Respiratory Medicine

Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods

(2020) Canrong Wu et al.   Acta Pharmaceutica Sinica B

Computational Design of ACE2-Based Peptide Inhibitors of SARS-CoV-2

(2020) Yanxiao Han et al.   ACS Nano

Letter to the Editor: Angiotensin-converting enzyme 2: an ally or a Trojan horse? Implications to SARS-CoV-2-related cardiovascular complications

(2020) Zaid Abassi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Downregulation of spinal angiotensin converting enzyme 2 is involved in neuropathic pain associated with type 2 diabetes mellitus in mice

(2020) Ryota Yamagata et al.   BIOCHEMICAL PHARMACOLOGY

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Angiotensin Converting Enzyme 2: A Double-Edged Sword

(2020) Kaiming Wang et al.   CIRCULATION

Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System

(2020) Mahmoud Gheblawi et al.   CIRCULATION RESEARCH

COVID-19 cytokine storm: The anger of inflammation

(2020) Mehdi Mahmudpour et al.   CYTOKINE

COVID-19, diabetes mellitus and ACE2: The conundrum

(2020) Rimesh Pal et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

The pivotal link between ACE2 deficiency and SARS-CoV-2 infection

(2020) Paolo Verdecchia et al.   European Journal of Internal Medicine

Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China

(2020) Chaomin Wu et al.   JAMA Internal Medicine

Individual variation of the SARS‐CoV‐2 receptor ACE2 gene expression and regulation

(2020) Jiawei Chen et al.   AGING CELL

Comorbid diabetes and the risk of disease severity or death among 8807 COVID-19 patients in China: A meta-analysis

(2020) Li Guo et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Electrocardiographic features of patients with COVID-19 pneumonia

(2020) Fabio Angeli et al.   European Journal of Internal Medicine

COVID-19

(2020) Paolo Verdecchia et al.   HYPERTENSION

Angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers and coronavirus

(2020) Paolo Verdecchia et al.   JOURNAL OF HYPERTENSION

Intoxication With Endogenous Angiotensin II: A COVID-19 Hypothesis

(2020) Adonis Sfera et al.   Frontiers in Immunology

Vasculopathy and Coagulopathy Associated with SARS-CoV-2 Infection

(2020) Nazzarena Labò et al.   Cells

Serum ACE-2, angiotensin II, and aldosterone levels are unchanged in patients with COVID-19

(2020) Marina Rieder et al.   AMERICAN JOURNAL OF HYPERTENSION

SARS-CoV-2 binds platelet ACE2 to enhance thrombosis in COVID-19

(2020) Si Zhang et al.   Journal of Hematology & Oncology

Risk factors for severe and critically ill COVID‐19 patients: A review

(2020) Ya‐dong Gao et al.   ALLERGY

The Counter Regulatory Axis of the Lung Renin-Angiotensin System in Severe COVID-19: Physiopathology and Clinical Implications

(2020) Filippos Triposkiadis et al.   Heart Lung and Circulation

Protective regulation of the ACE2/ACE gene expression by estrogen in human atrial tissue from elderly men

(2017) A Bukowska et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Landscape of X chromosome inactivation across human tissues

(2017) Taru Tukiainen et al.   NATURE

Role of the ACE2/Angiotensin 1–7 Axis of the Renin–Angiotensin System in Heart Failure

(2016) Vaibhav B. Patel et al.   CIRCULATION RESEARCH

Age-Associated Changes in the Vascular Renin-Angiotensin System in Mice

(2016) Hye Eun Yoon et al.   Oxidative Medicine and Cellular Longevity

Angiotensin-converting enzyme 2 inhibits lung injury induced by respiratory syncytial virus

(2016) Hongjing Gu et al.   Scientific Reports

Angiotensin II Mediates Angiotensin Converting Enzyme Type 2 Internalization and Degradation Through an Angiotensin II Type I Receptor–Dependent Mechanism

(2014) Matthew R. Deshotels et al.   HYPERTENSION

Angiotensin-converting enzyme 2 protects from lethal avian influenza A H5N1 infections

(2014) Zhen Zou et al.   Nature Communications

From gene to protein—experimental and clinical studies of ACE2 in blood pressure control and arterial hypertension

(2014) Sheila K. Patel et al.   Frontiers in Physiology

Multiple Functions of Angiotensin-Converting Enzyme 2 and Its Relevance in Cardiovascular Diseases

(2013) Keiji Kuba et al.   CIRCULATION JOURNAL

Acute respiratory distress syndrome leads to reduced ratio of ACE/ACE2 activities and is prevented by angiotensin-(1-7) or an angiotensin II receptor antagonist

(2011) Roelie M Wösten-van Asperen et al.   JOURNAL OF PATHOLOGY

Evidence that TMPRSS2 Activates the Severe Acute Respiratory Syndrome Coronavirus Spike Protein for Membrane Fusion and Reduces Viral Control by the Humoral Immune Response

(2011) I. Glowacka et al.   JOURNAL OF VIROLOGY

Role of HIF-1α in the regulation ACE and ACE2 expression in hypoxic human pulmonary artery smooth muscle cells

(2009) Ruifeng Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Loss of Angiotensin-Converting Enzyme 2 Accelerates Maladaptive Left Ventricular Remodeling in Response to Myocardial Infarction

(2009) Zamaneh Kassiri et al.   Circulation-Heart Failure

Angiotensin II Up-Regulates Angiotensin I-Converting Enzyme (ACE), but Down-Regulates ACE2 via the AT1-ERK/p38 MAP Kinase Pathway

(2008) Vijay Koka et al.   AMERICAN JOURNAL OF PATHOLOGY