- Home
- Publications
- Publication Search
- Publication Details
Title
Orphan nuclear receptor 4A1 (NR4A1) and novel ligands
Authors
Keywords
-
Journal
Essays in Biochemistry
Volume -, Issue -, Pages -
Publisher
Portland Press Ltd.
Online
2021-06-07
DOI
10.1042/ebc20200164
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Role of the Orphan Nuclear Receptor NR4A Family in T-Cell Biology
- (2021) Livia Odagiu et al. Frontiers in Endocrinology
- Targeting NR4A Nuclear Receptors to Control Stromal Cell Inflammation, Metabolism, Angiogenesis, and Tumorigenesis
- (2021) Daniel Crean et al. Frontiers in Cell and Developmental Biology
- A Bis-Indole–Derived NR4A1 Antagonist Induces PD-L1 Degradation and Enhances Antitumor Immunity
- (2020) Keshav Karki et al. CANCER RESEARCH
- BIS-INDOLE DERIVED NUCLEAR RECEPTOR 4A1 (NR4A1, Nur77) LIGANDS AS INHIBITORS OF ENDOMETRIOSIS
- (2020) Kumaravel Mohankumar et al. ENDOCRINOLOGY
- Reactivation of NR4A1 Restrains Chondrocyte Inflammation and Ameliorates Osteoarthritis in Rats
- (2020) Yan Xiong et al. Frontiers in Cell and Developmental Biology
- ‘Nur'turing tumor T cell tolerance and exhaustion: novel function for Nuclear Receptor Nur77 in immunity
- (2020) Sanne C. Lith et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The Paradoxical Roles of Orphan Nuclear Receptor 4A (NR4A) in Cancer
- (2020) Stephen Safe et al. MOLECULAR CANCER RESEARCH
- Blocking PPARγ interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression
- (2020) Peng-bo Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Assessment of NR4A Ligands That Directly Bind and Modulate the Orphan Nuclear Receptor Nurr1
- (2020) Paola Munoz-Tello et al. JOURNAL OF MEDICINAL CHEMISTRY
- THE HISTONE METHYLTRANSFERASE GENE G9A IS REGULATED BY NUCLEAR RECEPTOR 4A1 (NR4A1) IN ALVEOLAR RHABDOMYOSARCOMA CELLS
- (2020) Rupesh Shrestha et al. MOLECULAR CANCER THERAPEUTICS
- Nuclear Hormone Receptors and Their Ligands: Metabolites in Control of Transcription
- (2020) Lian Jing Tao et al. Cells
- BI1071, a novel Nur77 modulator, induces apoptosis of cancer cells by activating the Nur77-Bcl-2 apoptotic pathway
- (2019) Xiaohui Chen et al. MOLECULAR CANCER THERAPEUTICS
- Potent inhibition of breast cancer by bis-indole-derived nuclear receptor 4A1 (NR4A1) antagonists
- (2019) Erik Hedrick et al. BREAST CANCER RESEARCH AND TREATMENT
- Orphan nuclear receptor NR4A1 suppresses hyperhomocysteinemia‐induced hepatic steatosis in vitro and in vivo
- (2019) Hongjin Liang et al. FEBS LETTERS
- Nuclear receptor 4A1 (NR4A1) antagonists induce ROS-dependent inhibition of mTOR signaling in endometrial cancer
- (2019) Kumaravel Mohankumar et al. GYNECOLOGIC ONCOLOGY
- Molecular, Chemical, and Structural Characterization of Prostaglandin A2 as a Novel Agonist for Nur77
- (2019) Sowmya P Lakshmi et al. BIOCHEMICAL JOURNAL
- SAR study of celastrol analogs targeting Nur77-mediated inflammatory pathway
- (2019) Ziwen Chen et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Structural basis of binding of homodimers of the nuclear receptor NR4A2 to selective Nur-responsive DNA elements
- (2019) Longying Jiang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification
- (2019) Michele A. La Merrill et al. Nature Reviews Endocrinology
- Pharmacological activation of Nr4a rescues age-associated memory decline
- (2019) Snehajyoti Chatterjee et al. NEUROBIOLOGY OF AGING
- Drug targeting of NR4A nuclear receptors for treatment of acute myeloid leukemia
- (2018) Seth P. Boudreaux et al. LEUKEMIA
- New Drug Candidate Targeting the 4A1 Orphan Nuclear Receptor for Medullary Thyroid Cancer Therapy
- (2018) Lei Zhang et al. MOLECULES
- Oxidized analogs of Di(1H-indol-3-yl)methyl-4-substituted benzenes are NR4A1-dependent UPR inducers with potent and safe anti-cancer activity
- (2018) Marisa Sanchez et al. Oncotarget
- The Orphan Nuclear Receptor 4A1: A Potential New Therapeutic Target for Metabolic Diseases
- (2018) Lei Zhang et al. Journal of Diabetes Research
- Characteristics of Nur77 and its ligands as potential anticancer compounds (Review)
- (2018) Lingjuan Wu et al. Molecular Medicine Reports
- The effects of cytosporone-B, a novel antifibrotic agent, on vocal fold fibroblasts
- (2018) Nao Hiwatashi et al. LARYNGOSCOPE
- Transforming Growth Factor β/NR4A1-Inducible Breast Cancer Cell Migration and Epithelial-to-Mesenchymal Transition Is p38α (Mitogen-Activated Protein Kinase 14) Dependent
- (2017) Erik Hedrick et al. MOLECULAR AND CELLULAR BIOLOGY
- Celastrol-Induced Nur77 Interaction with TRAF2 Alleviates Inflammation by Promoting Mitochondrial Ubiquitination and Autophagy
- (2017) Mengjie Hu et al. MOLECULAR CELL
- Current perspective of diethylstilbestrol (DES) exposure in mothers and offspring
- (2017) Taher Al Jishi et al. REPRODUCTIVE TOXICOLOGY
- Nur77 attenuates endothelin-1 expression via downregulation of NF-κB and p38 MAPK in A549 cells and in an ARDS rat model
- (2016) Yujie Jiang et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- PAX3-FOXO1A Expression in Rhabdomyosarcoma Is Driven by the Targetable Nuclear Receptor NR4A1
- (2016) Alexandra Lacey et al. CANCER RESEARCH
- NR4A1-dependent Ly6Clowmonocytes contribute to reducing joint inflammation in arthritic mice through Treg cells
- (2016) Alexandre Brunet et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Penfluridol Represses Integrin Expression in Breast Cancer through Induction of Reactive Oxygen Species and Downregulation of Sp Transcription Factors
- (2016) Erik Hedrick et al. MOLECULAR CANCER THERAPEUTICS
- Pharmacological Activators of the NR4A Nuclear Receptors Enhance LTP in a CREB/CBP-Dependent Manner
- (2016) Morgan S Bridi et al. NEUROPSYCHOPHARMACOLOGY
- Nuclear receptor 4A1 (NR4A1) as a drug target for treating rhabdomyosarcoma (RMS)
- (2016) Alexandra Lacey et al. Oncotarget
- EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals
- (2015) A. C. Gore et al. ENDOCRINE REVIEWS
- Nuclear receptor 4A1 as a drug target for breast cancer chemotherapy
- (2015) Erik Hedrick et al. ENDOCRINE-RELATED CANCER
- Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation
- (2015) Li Li et al. Nature Chemical Biology
- Advances in our structural understanding of orphan nuclear receptors
- (2015) Nerea Gallastegui et al. TRENDS IN BIOCHEMICAL SCIENCES
- Nuclear Receptor 4A1 (NR4A1) as a Drug Target for Renal Cell Adenocarcinoma
- (2015) Erik Hedrick et al. PLoS One
- Diindolylmethane Analogs Bind NR4A1 and Are NR4A1 Antagonists in Colon Cancer Cells
- (2014) Syng-Ook Lee et al. MOLECULAR ENDOCRINOLOGY
- Novel Para-Phenyl Substituted Diindolylmethanes Protect Against MPTP Neurotoxicity and Suppress Glial Activation in a Mouse Model of Parkinson’s Disease
- (2014) Briana R. De Miranda et al. TOXICOLOGICAL SCIENCES
- Nuclear receptor NR4A1 promotes breast cancer invasion and metastasis by activating TGF-β signalling
- (2014) FangFang Zhou et al. Nature Communications
- Allosteric Controls of Nuclear Receptor Function in the Regulation of Transcription
- (2013) Isabelle Billas et al. JOURNAL OF MOLECULAR BIOLOGY
- Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway
- (2013) Wei-jia Wang et al. Nature Chemical Biology
- Structure-dependent activation of NR4A2 (Nurr1) by 1,1-bis(3′-indolyl)-1-(aromatic)methane analogs in pancreatic cancer cells
- (2012) Xi Li et al. BIOCHEMICAL PHARMACOLOGY
- The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK
- (2012) Yan-yan Zhan et al. Nature Chemical Biology
- Relative impact of 3- and 5-hydroxyl groups of cytosporone B on cancer cell viability
- (2012) Zebin Xia et al. MedChemComm
- Discovery of a Protein–Metabolite Interaction between Unsaturated Fatty Acids and the Nuclear Receptor Nur77 Using a Metabolomics Approach
- (2011) Nawaporn Vinayavekhin et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Structural basis for nuclear hormone receptor DNA binding
- (2011) Christine Helsen et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- The nuclear receptor TR3 regulates mTORC1 signaling in lung cancer cells expressing wild-type p53
- (2011) S-O Lee et al. ONCOGENE
- Inactivation of the Orphan Nuclear Receptor TR3/Nur77 Inhibits Pancreatic Cancer Cell and Tumor Growth
- (2010) S.-O. Lee et al. CANCER RESEARCH
- A Unique Pharmacophore for Activation of the Nuclear Orphan Receptor Nur77 In vivo and In vitro
- (2010) Jing-jing Liu et al. CANCER RESEARCH
- Minireview: Nuclear Hormone Receptor 4A Signaling: Implications for Metabolic Disease
- (2010) Michael A. Pearen et al. MOLECULAR ENDOCRINOLOGY
- Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas
- (2009) Neil J. McKenna et al. MOLECULAR ENDOCRINOLOGY
- Non-classical genomic estrogen receptor (ER)/specificity protein and ER/activating protein-1 signaling pathways
- (2008) Stephen Safe et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- Cytosporone B is an agonist for nuclear orphan receptor Nur77
- (2008) Yanyan Zhan et al. Nature Chemical Biology
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More