p53 as guardian of the mitochondrial genome

Cooperation of protein machineries in mitochondrial protein sorting

(2015) Lena-Sophie Wenz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Tumor suppressor p53 and its mutants in cancer metabolism

(2015) Juan Liu et al.   CANCER LETTERS

Mitochondrial DNA Variation in Human Radiation and Disease

(2015) Douglas C. Wallace   CELL

Bimolecular Fluorescence Complementation (BiFC) Analysis: Advances and Recent Applications for Genome-Wide Interaction Studies

(2015) Kristi E. Miller et al.   JOURNAL OF MOLECULAR BIOLOGY

The dynamics of mitochondrial DNA heteroplasmy: implications for human health and disease

(2015) James B. Stewart et al.   NATURE REVIEWS GENETICS

p53 in survival, death and metabolic health: a lifeguard with a licence to kill

(2015) Flore Kruiswijk et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cross-strand binding of TFAM to a single mtDNA molecule forms the mitochondrial nucleoid

(2015) Christian Kukat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial-nuclear DNA mismatch matters

(2015) K. J. Dunham-Snary et al.   SCIENCE

Protecting the mitochondrial powerhouse

(2015) Morten Scheibye-Knudsen et al.   TRENDS IN CELL BIOLOGY

Direct interaction between p53 and Tid1 proteins affects p53 mitochondrial localization and apoptosisy as a Target for Cancer Therapy?

(2015)   Oncotarget

Mitochondrial genome maintenance in health and disease

(2014) William C. Copeland et al.   DNA REPAIR

p53 Is Required for Cisplatin-induced Processing of the Mitochondrial Fusion Protein L-Opa1 That Is Mediated by the Mitochondrial Metallopeptidase Oma1 in Gynecologic Cancers

(2014) Bao Kong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective propagation of functional mitochondrial DNA during oogenesis restricts the transmission of a deleterious mitochondrial variant

(2014) Jahda H Hill et al.   NATURE GENETICS

Mitochondrial dynamics and inheritance during cell division, development and disease

(2014) Prashant Mishra et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Inhibition of p53 preserves Parkin-mediated mitophagy and pancreatic  -cell function in diabetes

(2014) A. Hoshino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RECQL4 and p53 potentiate the activity of polymerase γ and maintain the integrity of the human mitochondrial genome

(2013) Shruti Gupta et al.   CARCINOGENESIS

Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses

(2013) D. Kenzelmann Broz et al.   GENES & DEVELOPMENT

Increased Oxidative Metabolism in the Li–Fraumeni Syndrome

(2013) Ping-Yuan Wang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mitochondrial disulfide relay mediates translocation of p53 and partitions its subcellular activity

(2013) J. Zhuang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial DNA Genetics and the Heteroplasmy Conundrum in Evolution and Disease

(2013) D. C. Wallace et al.   Cold Spring Harbor Perspectives in Biology

Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart

(2013) Atsushi Hoshino et al.   Nature Communications

RECQL4 localizes to mitochondria and preserves mitochondrial DNA integrity

(2012) Deborah L. Croteau et al.   AGING CELL

p53 Opens the Mitochondrial Permeability Transition Pore to Trigger Necrosis

(2012) Angelina V. Vaseva et al.   CELL

Metabolic regulation of oxygen and redox homeostasis by p53: Lessons from evolutionary biology?

(2012) Jie Zhuang et al.   FREE RADICAL BIOLOGY AND MEDICINE

RECQL4 is essential for the transport of p53 to mitochondria in normal human cells in the absence of exogenous stress

(2012) S. De et al.   JOURNAL OF CELL SCIENCE

Physiological Roles of Mitochondrial Reactive Oxygen Species

(2012) Laura A. Sena et al.   MOLECULAR CELL

Minimizing the damage: repair pathways keep mitochondrial DNA intact

(2012) Lawrence Kazak et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitochondrial dysfunction in ataxia-telangiectasia

(2011) Y. A. Valentin-Vega et al.   BLOOD

Repair of persistent strand breaks in the mitochondrial genome

(2011) Peter Sykora et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect

(2011) C. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Mitochondrial Proteome and Human Disease

(2010) Sarah E. Calvo et al.   Annual Review of Genomics and Human Genetics

p53, Aerobic Metabolism, and Cancer

(2010) Cory U. Lago et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial Liaisons of p53

(2010) Lorenzo Galluzzi et al.   ANTIOXIDANTS & REDOX SIGNALING

Oxidation-driven protein import into mitochondria: Insights and blind spots

(2010) Jan Riemer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Autophagy regulation by p53

(2010) Maria Chiara Maiuri et al.   CURRENT OPINION IN CELL BIOLOGY

The mitochondrial transcription factor A functions in mitochondrial base excision repair

(2010) Chandrika Canugovi et al.   DNA REPAIR

Human mitochondrial transcription factor A is required for the segregation of mitochondrial DNA in cultured cells

(2010) Katsumi Kasashima et al.   EXPERIMENTAL CELL RESEARCH

Reconstitution of the mitochondrial Hsp70 (mortalin)-p53 interaction using purified proteins - Identification of additional interacting regions

(2010) Ohad Iosefson et al.   FEBS LETTERS

Mechanisms of mitophagy

(2010) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells

(2010) D.-F. Suen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial respiration protects against oxygen-associated DNA damage

(2010) Ho Joong Sung et al.   Nature Communications

miR-30 Regulates Mitochondrial Fission through Targeting p53 and the Dynamin-Related Protein-1 Pathway

(2010) Jincheng Li et al.   PLoS Genetics

Loss of p53 causes mitochondrial DNA depletion and altered mitochondrial reactive oxygen species homeostasis

(2009) Maria A. Lebedeva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Importing Mitochondrial Proteins: Machineries and Mechanisms

(2009) Agnieszka Chacinska et al.   CELL

p53 Improves Aerobic Exercise Capacity and Augments Skeletal Muscle Mitochondrial DNA Content

(2009) Joon-Young Park et al.   CIRCULATION RESEARCH

Cytoplasmic functions of the tumour suppressor p53

(2009) Douglas R. Green et al.   NATURE

Biophysical characterizations of human mitochondrial transcription factor A and its binding to tumor suppressor p53

(2009) Tuck Seng Wong et al.   NUCLEIC ACIDS RESEARCH

Membrane association of mitochondrial DNA facilitates base excision repair in mammalian mitochondria

(2009) Pierre Boesch et al.   NUCLEIC ACIDS RESEARCH

Tid1 is a new regulator of p53 mitochondrial translocation and apoptosis in cancer

(2009) B Y Ahn et al.   ONCOGENE

Expression and Maintenance of Mitochondrial DNA

(2008) Gerald S. Shadel   AMERICAN JOURNAL OF PATHOLOGY

p53 in mitochondria enhances the accuracy of DNA synthesis

(2008) M Bakhanashvili et al.   CELL DEATH AND DIFFERENTIATION

Bimodal Protein Targeting through Activation of Cryptic Mitochondrial Targeting Signals by an Inducible Cytosolic Endoprotease

(2008) Ettickan Boopathi et al.   MOLECULAR CELL

Physical and functional interactions between human mitochondrial single-stranded DNA-binding protein and tumour suppressor p53

(2008) T. S. Wong et al.   NUCLEIC ACIDS RESEARCH

A Mouse Model of Mitochondrial Disease Reveals Germline Selection Against Severe mtDNA Mutations

(2008) Weiwei Fan et al.   SCIENCE

Homeostatic functions of the p53 tumor suppressor: Regulation of energy metabolism and antioxidant defense

(2008) Ivan A. Olovnikov et al.   SEMINARS IN CANCER BIOLOGY