CDC20 promotes bone formation via APC/C dependent ubiquitination and degradation of p65

Lineage Tracing of Cells Expressing the Ciliary Gene IFT140 During Bone Development

(2020) Yubei Chen et al.   DEVELOPMENTAL DYNAMICS

Activated Complement Factors as Disease Markers for Sepsis

(2015) Jean Charchaflieh et al.   DISEASE MARKERS

Activation of the APC/C Ubiquitin Ligase by Enhanced E2 Efficiency

(2014) Vanessa A. Van Voorhis et al.   CURRENT BIOLOGY

APCCdc20 Suppresses Apoptosis through Targeting Bim for Ubiquitination and Destruction

(2014) Lixin Wan et al.   DEVELOPMENTAL CELL

A subset of chondrogenic cells provides early mesenchymal progenitors in growing bones

(2014) Noriaki Ono et al.   NATURE CELL BIOLOGY

The master cell cycle regulator APC-Cdc20 regulates ciliary length and disassembly of the primary cilium

(2014) Weiping Wang et al.   eLife

High CDC20 expression is associated with poor prognosis in oral squamous cell carcinoma

(2013) Inês M. B. Moura et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

High expression of spindle assembly checkpoint proteins CDC20 and MAD2 is associated with poor prognosis in urothelial bladder cancer

(2013) Jung-Woo Choi et al.   VIRCHOWS ARCHIV

Mad2 and the APC/C compete for the same site on Cdc20 to ensure proper chromosome segregation

(2012) Daisuke Izawa et al.   JOURNAL OF CELL BIOLOGY

Increased CDC20 expression is associated with pancreatic ductal adenocarcinoma differentiation and progression

(2012) David Z Chang et al.   Journal of Hematology & Oncology

PPARγ is an E3 ligase that induces the degradation of NFκB/p65

(2012) Yongzhong Hou et al.   Nature Communications

Cdh1 Regulates Osteoblast Function through an APC/C-Independent Modulation of Smurf1

(2011) Lixin Wan et al.   MOLECULAR CELL

Cubism and the cell cycle: the many faces of the APC/C

(2011) Jonathon Pines   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)- -TrCP, sequentially regulate glycolysis during the cell cycle

(2011) S. Tudzarova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel functions for the anaphase-promoting complex in neurobiology

(2011) Sidharth V. Puram et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

APC/C-Cdh1

(2010) Xinxian Qiao et al.   CELL CYCLE

Entamoeba histolyticaCysteine Proteinase 5 Binds Integrin on Colonic Cells and Stimulates NFκB-mediated Pro-inflammatory Responses

(2010) Yongzhong Hou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Anaphase-Promoting Complex/Cyclosome Activator Cdh1 Modulates Rho GTPase by Targeting p190 RhoGAP for Degradation

(2010) H. Naoe et al.   MOLECULAR AND CELLULAR BIOLOGY

Multiple functions of Osterix are required for bone growth and homeostasis in postnatal mice

(2010) X. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Centrosomal Cdc20-APC Pathway Controls Dendrite Morphogenesis in Postmitotic Neurons

(2009) Albert H. Kim et al.   CELL

Cdh1 Regulates Cell Cycle through Modulating the Claspin/Chk1 and the Rb/E2F1 Pathways

(2009) Daming Gao et al.   MOLECULAR BIOLOGY OF THE CELL

The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C–Cdh1

(2009) Angel Herrero-Mendez et al.   NATURE CELL BIOLOGY

The emerging role of APC/CCdh1 in controlling differentiation, genomic stability and tumor suppression

(2009) R Wäsch et al.   ONCOGENE

A Cdc20-APC Ubiquitin Signaling Pathway Regulates Presynaptic Differentiation

(2009) Y. Yang et al.   SCIENCE

The Cdc14B-Cdh1-Plk1 Axis Controls the G2 DNA-Damage-Response Checkpoint

(2008) Florian Bassermann et al.   CELL

CHIP promotes Runx2 degradation and negatively regulates osteoblast differentiation

(2008) Xueni Li et al.   JOURNAL OF CELL BIOLOGY

A Role for the Fizzy/Cdc20 Family of Proteins in Activation of the APC/C Distinct from Substrate Recruitment

(2008) Yuu Kimata et al.   MOLECULAR CELL