Fusobacterium nucleatum secretes amyloid‐like FadA to enhance pathogenicity

Fusobacterium nucleatum host-cell binding and invasion induces IL-8 and CXCL1 secretion that drives colorectal cancer cell migration

(2020) Michael A. Casasanta et al.   Science Signaling

Analysis of 16S rRNA genes reveals reduced Fusobacterial community diversity when translocating from saliva to GI sites

(2020) Miles Richardson et al.   Gut Microbes

Human colon mucosal biofilms from healthy or colon cancer hosts are carcinogenic

(2019) Sarah Tomkovich et al.   JOURNAL OF CLINICAL INVESTIGATION

Fusobacterium nucleatum promotes colorectal cancer by inducing Wnt/β‐catenin modulator Annexin A1

(2019) Mara Roxana Rubinstein et al.   EMBO REPORTS

Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation

(2019) Andrew Maltez Thomas et al.   NATURE MEDICINE

Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer

(2019) Jakob Wirbel et al.   NATURE MEDICINE

Periodontitis is associated with an increased risk for proximal colorectal neoplasms

(2019) Gun Woo Kim et al.   Scientific Reports

Utilizing Whole Fusobacterium Genomes to Identify, Correct, and Characterize Potential Virulence Protein Families

(2019) Ariana Umana et al.   JOURNAL OF BACTERIOLOGY

Increased Abundance of Clostridium and Fusobacterium in Gastric Microbiota of Patients with Gastric Cancer in Taiwan

(2018) Yung-Yu Hsieh et al.   Scientific Reports

Progress in characterizing the linkage between Fusobacterium nucleatum and gastrointestinal cancer

(2018) Yang Liu et al.   JOURNAL OF GASTROENTEROLOGY

The cytotoxic Staphylococcus aureus PSMα3 reveals a cross-α amyloid-like fibril

(2017) Einav Tayeb-Fligelman et al.   SCIENCE

Analysis ofFusobacteriumpersistence and antibiotic response in colorectal cancer

(2017) Susan Bullman et al.   SCIENCE

Amyloid-like Self-Assembly of a Cellular Compartment

(2016) Elvan Boke et al.   CELL

Fap2 Mediates Fusobacterium nucleatum Colorectal Adenocarcinoma Enrichment by Binding to Tumor-Expressed Gal-GalNAc

(2016) Jawad Abed et al.   Cell Host & Microbe

Regulated Formation of an Amyloid-like Translational Repressor Governs Gametogenesis

(2015) Luke E. Berchowitz et al.   CELL

Fusobacterium nucleatumin colorectal carcinoma tissue and patient prognosis

(2015) Kosuke Mima et al.   GUT

Fap2 of Fusobacterium nucleatum Is a Galactose-Inhibitable Adhesin Involved in Coaggregation, Cell Adhesion, and Preterm Birth

(2015) S. Coppenhagen-Glazer et al.   INFECTION AND IMMUNITY

Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis

(2015) Kei Mitsuhashi et al.   Oncotarget

Inexpensive Multiplexed Library Preparation for Megabase-Sized Genomes

(2015) Michael Baym et al.   PLoS One

Evolution of Invasion in a Diverse Set of Fusobacterium Species

(2014) Abigail Manson McGuire et al.   mBio

Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment

(2013) Aleksandar D. Kostic et al.   Cell Host & Microbe

Fusobacterium nucleatum Promotes Colorectal Carcinogenesis by Modulating E-Cadherin/β-Catenin Signaling via its FadA Adhesin

(2013) Mara Roxana Rubinstein et al.   Cell Host & Microbe

Comparative Microbial Analysis of Paired Amniotic Fluid and Cord Blood from Pregnancies Complicated by Preterm Birth and Early-Onset Neonatal Sepsis

(2013) Xiaowei Wang et al.   PLoS One

Identification of Oral Bacterial DNA in Synovial Fluid of Patients With Arthritis With Native and Failed Prosthetic Joints

(2012) Stéphanie Témoin et al.   JCR-JOURNAL OF CLINICAL RHEUMATOLOGY

Composition of the adult digestive tract bacterial microbiome based on seven mouth surfaces, tonsils, throat and stool samples

(2012) Nicola Segata et al.   GENOME BIOLOGY

Signal peptide of FadA adhesin fromFusobacterium nucleatumplays a novel structural role by modulating the filament's length and width

(2011) Stéphanie Témoin et al.   FEBS LETTERS

Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma

(2011) M. Castellarin et al.   GENOME RESEARCH

Genomic analysis identifies association of Fusobacterium with colorectal carcinoma

(2011) A. D. Kostic et al.   GENOME RESEARCH

Invasive potential of gut mucosa-derived fusobacterium nucleatum positively correlates with IBD status of the host

(2011) Jaclyn Strauss et al.   INFLAMMATORY BOWEL DISEASES

Fusobacterium nucleatum adhesin FadA binds vascular endothelial cadherin and alters endothelial integrity

(2011) Yann Fardini et al.   MOLECULAR MICROBIOLOGY

Fusobacterium nucleatum Outer Membrane Proteins Fap2 and RadD Induce Cell Death in Human Lymphocytes

(2010) C. W. Kaplan et al.   INFECTION AND IMMUNITY

Term Stillbirth Caused by Oral Fusobacterium nucleatum

(2010) Yiping W. Han et al.   OBSTETRICS AND GYNECOLOGY

Responses to Amyloids of Microbial and Host Origin Are Mediated through Toll-like Receptor 2

(2009) Çagla Tükel et al.   Cell Host & Microbe

Acute appendicitis is characterised by local invasion with Fusobacterium nucleatum/necrophorum

(2009) A. Swidsinski et al.   GUT

Complementation of the fadA Mutation in Fusobacterium nucleatum Demonstrates that the Surface-Exposed Adhesin Promotes Cellular Invasion and Placental Colonization

(2009) A. Ikegami et al.   INFECTION AND IMMUNITY

Periodontal Therapy Reduces the Severity of Active Rheumatoid Arthritis in Patients Treated With or Without Tumor Necrosis Factor Inhibitors

(2009) P. Ortiz et al.   JOURNAL OF PERIODONTOLOGY

Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation

(2009) Lynette Cegelski et al.   Nature Chemical Biology

Crystal Structure of FadA Adhesin fromFusobacterium nucleatumReveals a Novel Oligomerization Motif, the Leucine Chain

(2008) Stanley Nithianantham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Uncultivated Bacteria as Etiologic Agents of Intra-Amniotic Inflammation Leading to Preterm Birth

(2008) Y. W. Han et al.   JOURNAL OF CLINICAL MICROBIOLOGY

TheFusobacterium nucleatumouter membrane protein RadD is an arginine-inhibitable adhesin required for inter-species adherence and the structured architecture of multispecies biofilm

(2008) Christopher W. Kaplan et al.   MOLECULAR MICROBIOLOGY