Oxidative stress disassembles the p38/NPM/PP2A complex, which leads to modulation of nucleophosmin-mediated signaling to DNA damage response

Ceramide-Initiated Protein Phosphatase 2A Activation Contributes to Arterial Dysfunction In Vivo

(2015) Leena P. Bharath et al.   DIABETES

Leukemia-Associated Mutations in Nucleophosmin Alter Recognition by CRM1: Molecular Basis of Aberrant Transport

(2015) Igor Arregi et al.   PLoS One

DNA-PK: A dynamic enzyme in a versatile DSB repair pathway

(2014) Anthony J. Davis et al.   DNA REPAIR

Role of polyphenols in improving endothelial dysfunction in diabetes

(2014) Valérie Schini-Kerth   FREE RADICAL BIOLOGY AND MEDICINE

Targeting Nucleophosmin 1 Represents a Rational Strategy for Radiation Sensitization

(2014) Konjeti R. Sekhar et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Nucleophosmin modulates stability, activity, and nucleolar accumulation of base excision repair proteins

(2014) Mattia Poletto et al.   MOLECULAR BIOLOGY OF THE CELL

Phosphorylated STAT3 physically interacts with NPM and transcriptionally enhances its expression in cancer

(2014) Z Ren et al.   ONCOGENE

SnapShot: p38 MAPK Substrates

(2013) Natalia Trempolec et al.   CELL

DNA repair mechanisms in dividing and non-dividing cells

(2013) Teruaki Iyama et al.   DNA REPAIR

Oxidative stress induces inactivation of protein phosphatase 2A, promoting proinflammatory NF-κB in aged rat kidney

(2013) Kyung Jin Jung et al.   FREE RADICAL BIOLOGY AND MEDICINE

Membrane Signaling Induced by High Doses of Ionizing Radiation in the Endothelial Compartment. Relevance in Radiation Toxicity

(2013) Isabelle Corre et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nucleophosmin1 Is a Negative Regulator of the Small GTPase Rac1

(2013) Younes Zoughlami et al.   PLoS One

The B55α-containing PP2A holoenzyme dephosphorylates FOXO1 in islet β-cells under oxidative stress

(2012) Ling Yan et al.   BIOCHEMICAL JOURNAL

Nucleophosmin/B23 activates Aurora A at the centrosome through phosphorylation of serine 89

(2012) David Reboutier et al.   JOURNAL OF CELL BIOLOGY

In silico studies of potential phosphoresidues in the human nucleophosmin/B23: Its kinases and related biological processes

(2012) Gioser Ramos-Echazábal et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Nucleolar NF-κB/RelA mediates apoptosis by causing cytoplasmic relocalization of nucleophosmin

(2011) N Khandelwal et al.   CELL DEATH AND DIFFERENTIATION

The Novel Chemical Entity YTR107 Inhibits Recruitment of Nucleophosmin to Sites of DNA Damage, Suppressing Repair of DNA Double-Strand Breaks and Enhancing Radiosensitization

(2011) K. R. Sekhar et al.   CLINICAL CANCER RESEARCH

Effects of Salvianolic Acid B on Protein Expression in Human Umbilical Vein Endothelial Cells

(2011) Tsong-Min Chang et al.   Evidence-based Complementary and Alternative Medicine

Mitochondrial c-Jun N-terminal Kinase (JNK) Signaling Initiates Physiological Changes Resulting in Amplification of Reactive Oxygen Species Generation

(2011) Jeremy W. Chambers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recruitment of Phosphorylated NPM1 to Sites of DNA Damage through RNF8-Dependent Ubiquitin Conjugates

(2010) A. Koike et al.   CANCER RESEARCH

Reactive oxygen species and vascular biology: implications in human hypertension

(2010) Rhian M Touyz et al.   HYPERTENSION RESEARCH

Regulation of Vascular Endothelial Growth Factor-induced Endothelial Cell Migration by LIM Kinase 1-mediated Phosphorylation of Annexin 1

(2010) Maxime C. Côté et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ataxia Telangiectasia Mutated (ATM)-mediated DNA Damage Response in Oxidative Stress-induced Vascular Endothelial Cell Senescence

(2010) Hong Zhan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dephosphorylation of Nucleophosmin by PP1β Facilitates pRB Binding and Consequent E2F1-dependent DNA Repair

(2010) Chiao Yun Lin et al.   MOLECULAR BIOLOGY OF THE CELL

Nucleophosmin Phosphorylation by v-Cyclin-CDK6 Controls KSHV Latency

(2010) Grzegorz Sarek et al.   PLoS Pathogens

Nucleophosmin Redistribution following Heat Shock: A Role in Heat-Induced Radiosensitization

(2009) R. P. Vanderwaal et al.   CANCER RESEARCH

Oxidative Stress, Endothelial Dysfunction and Atherosclerosis

(2009) Victor Victor et al.   CURRENT PHARMACEUTICAL DESIGN

Hydrogen peroxide induces DNA single- and double-strand breaks in thyroid cells and is therefore a potential mutagen for this organ

(2009) Natacha Driessens et al.   ENDOCRINE-RELATED CANCER

Role of LOX-1 in monocyte adhesion-triggered redox, Akt/eNOS and Ca2+signaling pathways in endothelial cells

(2009) Nobuo Sakamoto et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Potentiation of vascular oxidative stress and nitric oxide-mediated endothelial dysfunction by high-fat diet in a mouse model of estrogen deficiency and hyperandrogenemia

(2009) Danesh Javeshghani et al.   Journal of the American Society of Hypertension

Altered nucleophosmin transport in acute myeloid leukaemia with mutated NPM1: molecular basis and clinical implications

(2009) B Falini et al.   LEUKEMIA

p38MAPK: stress responses from molecular mechanisms to therapeutics

(2009) Lydia R. Coulthard et al.   TRENDS IN MOLECULAR MEDICINE

p38 mitogen-activated protein kinase inhibitor LY2228820 enhances bortezomib-induced cytotoxicity and inhibits osteoclastogenesis in multiple myeloma; therapeutic implications

(2008) Kenji Ishitsuka et al.   BRITISH JOURNAL OF HAEMATOLOGY

Inflammation and endothelial dysfunction during aging: role of NF-κB

(2008) Anna Csiszar et al.   JOURNAL OF APPLIED PHYSIOLOGY

Regulation of endothelial barrier function by reactive oxygen and nitrogen species

(2008) Adel Boueiz et al.   MICROVASCULAR RESEARCH