Membrane Signaling Induced by High Doses of Ionizing Radiation in the Endothelial Compartment. Relevance in Radiation Toxicity

Ceramide mediates lung fibrosis in cystic fibrosis

(2013) Regan Ziobro et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Therapy of CF-Patients with Amitriptyline and Placebo - a Randomised, Double-Blind, Placebo-Controlled Phase IIb Multicenter, Cohort-Study

(2013) Lutz Nährlich et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Strategies for optimizing the response of cancer and normal tissues to radiation

(2013) Everett J. Moding et al.   NATURE REVIEWS DRUG DISCOVERY

Rho family GTPases

(2012) Alan Hall   BIOCHEMICAL SOCIETY TRANSACTIONS

Radiobiologie appliquée à l’endothélium

(2012) S. Supiot et al.   Cancer Radiotherapie

Lysosome fusion to the cell membrane is mediated by the dysferlin C2A domain in coronary arterial endothelial cells

(2012) W.-Q. Han et al.   JOURNAL OF CELL SCIENCE

Anti-ceramide antibody prevents the radiation gastrointestinal syndrome in mice

(2012) Jimmy Rotolo et al.   JOURNAL OF CLINICAL INVESTIGATION

TRAIL death receptor 4 signaling via lysosome fusion and membrane raft clustering in coronary arterial endothelial cells: evidence from ASM knockout mice

(2012) Xiang Li et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Requirement of translocated lysosomal V1 H+-ATPase for activation of membrane acid sphingomyelinase and raft clustering in coronary endothelial cells

(2012) Ming Xu et al.   MOLECULAR BIOLOGY OF THE CELL

Stereotactic body radiation therapy for abdominal oligometastases: a biological and clinical review

(2012) Mohammed Almaghrabi et al.   Radiation Oncology

Mast Cells and Ionizing Radiation Induce a Synergistic Expression of Inflammatory Genes in Endothelial Cells by a Mechanism Involving p38α MAP Kinase and (p65) NF-κB Activation

(2012) Karl Blirando et al.   RADIATION RESEARCH

RhoA GTPase regulates radiation-induced alterations in endothelial cell adhesion and migration

(2011) Matthieu Rousseau et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ionizing radiation-induced metabolic oxidative stress and prolonged cell injury

(2011) Edouard I. Azzam et al.   CANCER LETTERS

Identification of Novel Functional Inhibitors of Acid Sphingomyelinase

(2011) Johannes Kornhuber et al.   PLoS One

Sphingosine-1-phosphate signaling and its role in disease

(2011) Michael Maceyka et al.   TRENDS IN CELL BIOLOGY

Recent advances in radiotherapy

(2010) SA Bhide et al.   BMC Medicine

Sphingosine-1-Phosphate Activates the AKT Pathway to Protect Small Intestines from Radiation-Induced Endothelial Apoptosis

(2010) S. Bonnaud et al.   CANCER RESEARCH

Small Molecule Inhibitors of Acid Sphingomyelinase

(2010) Christoph Arenz   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): A Novel Pharmacological Group of Drugs with Broad Clinical Applications

(2010) Johannes Kornhuber et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Caspase-8 and caspase-7 sequentially mediate proteolytic activation of acid sphingomyelinase in TNF-R1 receptosomes

(2010) Bärbel Edelmann et al.   EMBO JOURNAL

Ceramide-rich platforms in transmembrane signaling

(2010) Branka Stancevic et al.   FEBS LETTERS

Effect of Irradiation on Microvascular Endothelial Cells of Parotid Glands in the Miniature Pig

(2010) Junji Xu et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Syntaxin 4 Is Required for Acid Sphingomyelinase Activity and Apoptotic Function

(2010) Cristiana Perrotta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endothelial Membrane Remodeling Is Obligate for Anti-Angiogenic Radiosensitization during Tumor Radiosurgery

(2010) Jean-Philip Truman et al.   PLoS One

Activation of Membrane NADPH Oxidase Associated with Lysosome-Targeted Acid Sphingomyelinase in Coronary Endothelial Cells

(2009) Jun-Xiang Bao et al.   ANTIOXIDANTS & REDOX SIGNALING

Phosphorylation of endothelial nitric oxide synthase by atypical PKC  contributes to angiopoietin-1-dependent inhibition of VEGF-induced endothelial permeability in vitro

(2009) M. Oubaha et al.   BLOOD

A Ceramide-binding C1 Domain Mediates Kinase Suppressor of Ras Membrane Translocation

(2009) Xianglei Yin et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Sphingomyelin metabolism at the plasma membrane: Implications for bioactive sphingolipids

(2009) Delphine Milhas et al.   FEBS LETTERS

Pravastatin Limits Radiation-Induced Vascular Dysfunction in the Skin

(2009) Valerie Holler et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Stereotactic body radiation therapy: a novel treatment modality

(2009) Simon S. Lo et al.   Nature Reviews Clinical Oncology

Rôle de l’endothélium dans les dommages radio-induits aux tissus sains

(2008) F. Milliat et al.   ANNALES DE CARDIOLOGIE ET D ANGEIOLOGIE

Ceramide-enriched membrane domains—Structure and function

(2008) Yang Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Peroxynitrite-dependent activation of protein phosphatase type 2A mediates microvascular endothelial barrier dysfunction

(2008) F. Wu et al.   CARDIOVASCULAR RESEARCH

NADPH oxidase mediates radiation-induced oxidative stress in rat brain microvascular endothelial cells

(2008) J. Racquel Collins-Underwood et al.   FREE RADICAL BIOLOGY AND MEDICINE

High-Dose Single-Fraction Radiotherapy: Exploiting a New Biology?

(2008) J. Martin Brown et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Normal tissue toxicity after small field hypofractionated stereotactic body radiation

(2008) Michael T Milano et al.   Radiation Oncology

Critical Role of Lipid Raft Redox Signaling Platforms in Endostatin-Induced Coronary Endothelial Dysfunction

(2007) Si Jin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A novel role for protein kinase Cδ-mediated phosphorylation of acid sphingomyelinase in UV light-induced mitochondrial injury

(2007) Youssef H. Zeidan et al.   FASEB JOURNAL