Artemisitene activates the Nrf2-dependent antioxidant response and protects against bleomycin-induced lung injury

Oncogenic KRAS Confers Chemoresistance by Upregulating NRF2

(2014) S. Tao et al.   CANCER RESEARCH

Oxaliplatin activates the Keap1/Nrf2 antioxidant system conferring protection against the cytotoxicity of anticancer drugs

(2014) Xiu Jun Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protective and Therapeutic Effect of Molsidomine on Bleomycin-Induced Lung Fibrosis in Rats

(2014) Talat Kilic et al.   INFLAMMATION

Tanshinone I Activates the Nrf2-Dependent Antioxidant Response and Protects Against As(III)-Induced Lung Inflammation In Vitro and In Vivo

(2013) Shasha Tao et al.   ANTIOXIDANTS & REDOX SIGNALING

The emerging role of the Nrf2-Keap1 signaling pathway in cancer

(2013) M. C. Jaramillo et al.   GENES & DEVELOPMENT

Nrf2 suppresses lupus nephritis through inhibition of oxidative injury and the NF-κB-mediated inflammatory response

(2013) Tao Jiang et al.   KIDNEY INTERNATIONAL

Dysregulated Proinflammatory and Fibrogenic Phenotype of Fibroblasts in Cystic Fibrosis

(2013) François Huaux et al.   PLoS One

Bardoxolone Brings Nrf2-Based Therapies to Light

(2012) Donna D. Zhang   ANTIOXIDANTS & REDOX SIGNALING

Crosstalk between Nrf2 and the proteasome: Therapeutic potential of Nrf2 inducers in vascular disease and aging

(2012) Sarah J. Chapple et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

PALB2 Interacts with KEAP1 To Promote NRF2 Nuclear Accumulation and Function

(2012) J. Ma et al.   MOLECULAR AND CELLULAR BIOLOGY

Sulforaphane prevents pulmonary damage in response to inhaled arsenic by activating the Nrf2-defense response

(2012) Yi Zheng et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Therapeutic Potential of Nrf2 Activators in Streptozotocin-Induced Diabetic Nephropathy

(2011) Hongting Zheng et al.   DIABETES

KEAP1 gene mutations and NRF2 activation are common in pulmonary papillary adenocarcinoma

(2011) Qing Kay Li et al.   JOURNAL OF HUMAN GENETICS

Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism

(2011) D. Ren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting Nrf2 Signaling Improves Bacterial Clearance by Alveolar Macrophages in Patients with COPD and in a Mouse Model

(2011) C. J. Harvey et al.   Science Translational Medicine

The Nrf2-Keap1-ARE Signaling Pathway: The Regulation and Dual Function of Nrf2 in Cancer

(2010) Donna D. Zhang   ANTIOXIDANTS & REDOX SIGNALING

Cancer Chemoprevention Mechanisms Mediated Through the Keap1–Nrf2 Pathway

(2010) John D. Hayes et al.   ANTIOXIDANTS & REDOX SIGNALING

Regulation of the Nrf2–Keap1 Antioxidant Response by the Ubiquitin Proteasome System: An Insight into Cullin-Ring Ubiquitin Ligases

(2010) Nicole F. Villeneuve et al.   ANTIOXIDANTS & REDOX SIGNALING

BMP-7 as antagonist of organ fibrosis

(2010) Ralf Weiskirchen   Frontiers in Bioscience-Landmark

A Noncanonical Mechanism of Nrf2 Activation by Autophagy Deficiency: Direct Interaction between Keap1 and p62

(2010) A. Lau et al.   MOLECULAR AND CELLULAR BIOLOGY

Role of Proinflammatory Cytokines IL-18 and IL-1β in Bleomycin-Induced Lung Injury in Humans and Mice

(2009) Tomoaki Hoshino et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Direct Interaction between Nrf2 and p21Cip1/WAF1 Upregulates the Nrf2-Mediated Antioxidant Response

(2009) Weimin Chen et al.   MOLECULAR CELL

Nrf2 protects against As(III)-induced damage in mouse liver and bladder

(2009) Tao Jiang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2

(2008) X.-J. Wang et al.   CARCINOGENESIS

Oridonin Confers Protection against Arsenic-Induced Toxicity through Activation of the Nrf2-Mediated Defensive Response

(2008) Yu Du et al.   ENVIRONMENTAL HEALTH PERSPECTIVES