Importance of adipocyte cyclooxygenase-2 and prostaglandin E2–prostaglandin E receptor 3 signaling in the development of obesity-induced adipose tissue inflammation and insulin resistance

Prostaglandin E2-induced inflammation: Relevance of prostaglandin E receptors

(2015) Kohichi Kawahara et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Human Adipocytes Induce Inflammation and Atrophy in Muscle Cells During Obesity

(2015) Vanessa Pellegrinelli et al.   DIABETES

Proinsulin-producing, hyperglycemia-induced adipose tissue macrophages underlie insulin resistance in high fat-fed diabetic mice

(2015) Eric Dale Buras et al.   FASEB JOURNAL

Nutrient and immune sensing are obligate pathways in metabolism, immunity, and disease

(2015) Abishek Iyer et al.   FASEB JOURNAL

Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity

(2015) Elise Dalmas et al.   NATURE MEDICINE

NPY antagonism reduces adiposity and attenuates age-related imbalance of adipose tissue metabolism

(2014) Seongjoon Park et al.   FASEB JOURNAL

Activation of prostaglandin E2-EP4 signaling reduces chemokine production in adipose tissue

(2014) Eva H. C. Tang et al.   JOURNAL OF LIPID RESEARCH

Prostaglandin E2 Receptor, EP3, Is Induced in Diabetic Islets and Negatively Regulates Glucose- and Hormone-Stimulated Insulin Secretion

(2013) M. E. Kimple et al.   DIABETES

Increased Saturated Fatty Acids in Obesity Alter Resolution of Inflammation in Part by Stimulating Prostaglandin Production

(2013) J. Hellmann et al.   JOURNAL OF IMMUNOLOGY

Prostaglandin E2-EP3 Signaling Induces Inflammatory Swelling by Mast Cell Activation

(2013) K. Morimoto et al.   JOURNAL OF IMMUNOLOGY

Endogenous oxidative stress, but not ER stress, induces hypoxia-independent VEGF120release through PI3K-dependent pathways in 3T3-L1 adipocytes

(2013) Kazuto Takahashi et al.   Obesity

CD36 level and trafficking are determinants of lipolysis in adipocytes

(2012) Dequan Zhou et al.   FASEB JOURNAL

Prostaglandins and Inflammation

(2011) Emanuela Ricciotti et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Innate immunity, insulin resistance and type 2 diabetes

(2011) J. M. Fernández-Real et al.   DIABETOLOGIA

Inhibition of prostaglandin E2 EP3 receptors improves stroke injury via anti-inflammatory and anti-apoptotic mechanisms

(2011) Yuri Ikeda-Matsuo et al.   JOURNAL OF NEUROIMMUNOLOGY

Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009

(2010) R. A. DeFronzo   DIABETOLOGIA

Cyclooxygenase-2 Deficiency Attenuates Adipose Tissue Differentiation and Inflammation in Mice

(2010) Sarbani Ghoshal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Suppressive effect of COX2 inhibitor on the progression of adipose inflammation in high-fat-induced obese rats

(2009) P.-S. Hsieh et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Cyclooxygenase-2 inhibition reverts the decrease in adiponectin levels and attenuates the loss of white adipose tissue during chronic inflammation

(2009) Miriam Granado et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Glucocorticoids and Thiazolidinediones Interfere with Adipocyte-mediated Macrophage Chemotaxis and Recruitment

(2009) David Patsouris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency

(2009) Kathy Jaworski et al.   NATURE MEDICINE

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

(2009) Satoshi Nishimura et al.   NATURE MEDICINE

JNK- and IκB-dependent pathways regulate MCP-1 but not adiponectin release from artificially hypertrophied 3T3-L1 adipocytes preloaded with palmitate in vitro

(2008) Kazuto Takahashi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

T-lymphocyte Infiltration in Visceral Adipose Tissue

(2008) Ulrich Kintscher et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Human SGBS Cells – a Unique Tool for Studies of Human Fat Cell Biology

(2008) Pamela Fischer-Posovszky et al.   Obesity Facts

Prostaglandin as a Target Molecule for Pharmacotherapy of Allergic Inflammatory Diseases

(2008) Hiroichi Nagai   ALLERGOLOGY INTERNATIONAL