Proinsulin-producing, hyperglycemia-induced adipose tissue macrophages underlie insulin resistance in high fat-fed diabetic mice

Metabolic Dysfunction Drives a Mechanistically Distinct Proinflammatory Phenotype in Adipose Tissue Macrophages

(2014) Mario Kratz et al.   Cell Metabolism

Bone marrow-derived TNF-α causes diabetic neuropathy in mice

(2014) Hiroshi Urabe et al.   DIABETOLOGIA

Hyperglycemia induces abnormal gene expression in hematopoietic stem cells and their progeny in diabetic neuropathy

(2014) Miwako Katagi et al.   FEBS LETTERS

Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production

(2014) Aurora Merovci et al.   JOURNAL OF CLINICAL INVESTIGATION

Metabolic response to sodium-glucose cotransporter 2 inhibition in type 2 diabetic patients

(2014) Ele Ferrannini et al.   JOURNAL OF CLINICAL INVESTIGATION

Emerging roles of hematopoietic cells in the pathobiology of diabetic complications

(2014) Hideto Kojima et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Metabolic inflammation: role of cytokines in the crosstalk between adipose tissue and liver

(2013) Romana R. Gerner et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Adipose Tissue Macrophages: Amicus adipem?

(2013) Justin I. Odegaard et al.   Cell Metabolism

Obesity Activates a Program of Lysosomal-Dependent Lipid Metabolism in Adipose Tissue Macrophages Independently of Classic Activation

(2013) Xiaoyuan Xu et al.   Cell Metabolism

Hyperglycemia Promotes Myelopoiesis and Impairs the Resolution of Atherosclerosis

(2013) Prabhakara R. Nagareddy et al.   Cell Metabolism

Evaluation of the anti-inflammatory effects of phloretin and phlorizin in lipopolysaccharide-stimulated mouse macrophages

(2012) Wei-Tien Chang et al.   FOOD CHEMISTRY

The vagus nerve and the inflammatory reflex—linking immunity and metabolism

(2012) Valentin A. Pavlov et al.   Nature Reviews Endocrinology

Diabetes Adversely Affects Macrophages During Atherosclerotic Plaque Regression in Mice

(2011) S. Parathath et al.   DIABETES

Multimodality Imaging of  -Cells in Mouse Models of Type 1 and 2 Diabetes

(2011) J. Yong et al.   DIABETES

Chronic insulin therapy reduces adipose tissue macrophage content in LDL-receptor-deficient mice

(2011) J. Yoon et al.   DIABETOLOGIA

Bone marrow expression of poly(ADP-ribose) polymerase underlies diabetic neuropathy via hematopoietic-neuronal cell fusion

(2011) Tomoya Terashima et al.   FASEB JOURNAL

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

(2011) Bolormaa Vandanmagsar et al.   NATURE MEDICINE

Free fatty acids in the presence of high glucose amplify monocyte inflammation via Toll-like receptors

(2010) Mohan R. Dasu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The Triterpenoid 2-Cyano-3,12-dioxooleana-1,9-dien-28-oic-acid Methyl Ester Has Potent Anti-diabetic Effects in Diet-induced Diabetic Mice andLeprdb/dbMice

(2010) Pradip K. Saha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hematopoietic Cell-Specific Deletion of Toll-like Receptor 4 Ameliorates Hepatic and Adipose Tissue Insulin Resistance in High-Fat-Fed Mice

(2009) Maziyar Saberi et al.   Cell Metabolism

Regulatory Mechanisms for Adipose Tissue M1 and M2 Macrophages in Diet-Induced Obese Mice

(2009) S. Fujisaka et al.   DIABETES

MGL1 promotes adipose tissue inflammation and insulin resistance by regulating 7/4himonocytes in obesity

(2009) Daniel J. Westcott et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Insulin as an Anti-Inflammatory and Antiatherogenic Modulator

(2009) Paresh Dandona et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Adipose Macrophage Infiltration Is Associated With Insulin Resistance and Vascular Endothelial Dysfunction in Obese Subjects

(2008) Caroline M. Apovian et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Ablation of CD11c-Positive Cells Normalizes Insulin Sensitivity in Obese Insulin Resistant Animals

(2008) David Patsouris et al.   Cell Metabolism

Phenotypic Switching of Adipose Tissue Macrophages With Obesity Is Generated by Spatiotemporal Differences in Macrophage Subtypes

(2008) C. N. Lumeng et al.   DIABETES