NPY antagonism reduces adiposity and attenuates age-related imbalance of adipose tissue metabolism

Ablation of PRDM16 and Beige Adipose Causes Metabolic Dysfunction and a Subcutaneous to Visceral Fat Switch

(2014) Paul Cohen et al.   CELL

A key role for neuropeptide Y in lifespan extension and cancer suppression via dietary restriction

(2014) Takuya Chiba et al.   Scientific Reports

Sirtuin deacetylases in neurodegenerative diseases of aging

(2013) Adrianna Z Herskovits et al.   CELL RESEARCH

MicroRNA-146b promotes adipogenesis by suppressing the SIRT1-FOXO1 cascade

(2013) Jiyun Ahn et al.   EMBO Molecular Medicine

Antiobese function of platelet-activating factor: increased adiposity in platelet-activating factor receptor-deficient mice with age

(2013) Junko Sugatani et al.   FASEB JOURNAL

Aging and long-term caloric restriction regulate neuropeptide Y receptor subtype densities in the rat brain

(2013) Christelle Veyrat-Durebex et al.   NEUROPEPTIDES

Aging leads to a programmed loss of brown adipocytes in murine subcutaneous white adipose tissue

(2012) Nicole H. Rogers et al.   AGING CELL

Central nervous system neuropeptide Y signaling via the Y1 receptor partially dissociates feeding behavior from lipoprotein metabolism in lean rats

(2012) Jennifer M. Rojas et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

High-Fat Diet Triggers Inflammation-Induced Cleavage of SIRT1 in Adipose Tissue To Promote Metabolic Dysfunction

(2012) Angeliki Chalkiadaki et al.   Cell Metabolism

A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism

(2012) Mark A. Herman et al.   NATURE

Sexual Dimorphic Regulation of Body Weight Dynamics and Adipose Tissue Lipolysis

(2012) Verena Benz et al.   PLoS One

Knockdown of NPY Expression in the Dorsomedial Hypothalamus Promotes Development of Brown Adipocytes and Prevents Diet-Induced Obesity

(2011) Pei-Ting Chao et al.   Cell Metabolism

CREB and ChREBP oppositely regulate SIRT1 expression in response to energy availability

(2011) Lilia G Noriega et al.   EMBO REPORTS

SIRT1 controls lipolysis in adipocytes via FOXO1-mediated expression of ATGL

(2011) Partha Chakrabarti et al.   JOURNAL OF LIPID RESEARCH

The cAMP/PKA Pathway Rapidly Activates SIRT1 to Promote Fatty Acid Oxidation Independently of Changes in NAD+

(2011) Zachary Gerhart-Hines et al.   MOLECULAR CELL

Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway

(2011) Hyunkyung Jeong et al.   NATURE MEDICINE

Estrogen inhibits NPY secretion through membrane-associated estrogen receptor (ER)-α in clonal, immortalized hypothalamic neurons

(2010) S S Dhillon et al.   INTERNATIONAL JOURNAL OF OBESITY

Agrp Neurons Mediate Sirt1's Action on the Melanocortin System and Energy Balance: Roles for Sirt1 in Neuronal Firing and Synaptic Plasticity

(2010) M. O. Dietrich et al.   JOURNAL OF NEUROSCIENCE

Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies

(2009) Prospective Studies Collaboration   LANCET

Lipolysis and lipid mobilization in human adipose tissue

(2009) Max Lafontan et al.   PROGRESS IN LIPID RESEARCH

Visceral adipose tissue modulates mammalian longevity

(2008) Radhika Muzumdar et al.   AGING CELL

Cardiac overexpression of hormone-sensitive lipase inhibits myocardial steatosis and fibrosis in streptozotocin diabetic mice

(2008) Masami Ueno et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Identification of a Lipokine, a Lipid Hormone Linking Adipose Tissue to Systemic Metabolism

(2008) Haiming Cao et al.   CELL

Neuropeptide Y is produced in visceral adipose tissue and promotes proliferation of adipocyte precursor cells via the Y1 receptor

(2008) Kaiping Yang et al.   FASEB JOURNAL

Hepatic Overexpression of Hormone-sensitive Lipase and Adipose Triglyceride Lipase Promotes Fatty Acid Oxidation, Stimulates Direct Release of Free Fatty Acids, and Ameliorates Steatosis

(2008) Brendan N. Reid et al.   JOURNAL OF BIOLOGICAL CHEMISTRY