The emerging role of GATA transcription factors in development and disease

Mutational Cooperativity Linked to Combinatorial Epigenetic Gain of Function in Acute Myeloid Leukemia

(2015) Alan H. Shih et al.   CANCER CELL

Regulation of GATA-binding Protein 2 Levels via Ubiquitin-dependent Degradation by Fbw7

(2015) Tomomi Nakajima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A microarray-based DNA methylation study of glioblastoma multiforme

(2014) Ramon Martinez et al.   Epigenetics

The promise of methylation on beads for cancer detection and treatment

(2014) Angela A Guzzetta et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Divergent functions of hematopoietic transcription factors in lineage priming and differentiation during erythro-megakaryopoiesis

(2014) Maxim Pimkin et al.   GENOME RESEARCH

Are GATA1 mutations occurring at random in Down syndrome transient leukemia?

(2014) Daniel Satgé   MEDICAL HYPOTHESES

Fbw7 Targets GATA3 through Cyclin-Dependent Kinase 2-Dependent Proteolysis and Contributes to Regulation of T-Cell Development

(2014) K. Kitagawa et al.   MOLECULAR AND CELLULAR BIOLOGY

Altered translation of GATA1 in Diamond-Blackfan anemia

(2014) Leif S Ludwig et al.   NATURE MEDICINE

Cyclin D2 is a GATA4 cofactor in cardiogenesis

(2014) A. Yamak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exome sequencing identifies putative drivers of progression of transient myeloproliferative disorder to AMKL in infants with Down syndrome

(2013) S. I. Nikolaev et al.   BLOOD

The Gata1 5' region harbors distinct cis-regulatory modules that direct gene activation in erythroid cells and gene inactivation in HSCs

(2013) J. Takai et al.   BLOOD

GATA1-mutant clones are frequent and often unsuspected in babies with Down syndrome: identification of a population at risk of leukemia

(2013) I. Roberts et al.   BLOOD

Control of Alveolar Differentiation by the Lineage Transcription Factors GATA6 and HOPX Inhibits Lung Adenocarcinoma Metastasis

(2013) William K.C. Cheung et al.   CANCER CELL

GATA3 controls the specification of prosensory domain and neuronal survival in the mouse cochlea

(2013) Xiong-jian Luo et al.   HUMAN MOLECULAR GENETICS

HPV-related methylation signature predicts survival in oropharyngeal squamous cell carcinomas

(2013) Efterpi Kostareli et al.   JOURNAL OF CLINICAL INVESTIGATION

AKT collaborates with ERG and Gata1s to dysregulate megakaryopoiesis and promote AMKL

(2013) M J Stankiewicz et al.   LEUKEMIA

GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression

(2013) Jonathan Chou et al.   NATURE CELL BIOLOGY

The landscape of somatic mutations in Down syndrome–related myeloid disorders

(2013) Kenichi Yoshida et al.   NATURE GENETICS

Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse

(2013) Virginia Perez-Andreu et al.   NATURE GENETICS

Expression and regulation of intergenic long noncoding RNAs during T cell development and differentiation

(2013) Gangqing Hu et al.   NATURE IMMUNOLOGY

GATA-3 controls the maintenance and proliferation of T cells downstream of TCR and cytokine signaling

(2013) Yunqi Wang et al.   NATURE IMMUNOLOGY

GATA-3 regulates the self-renewal of long-term hematopoietic stem cells

(2013) Catherine Frelin et al.   NATURE IMMUNOLOGY

Core Transcriptional Regulatory Circuit Controlled by the TAL1 Complex in Human T Cell Acute Lymphoblastic Leukemia

(2012) Takaomi Sanda et al.   CANCER CELL

The GATA2 Transcriptional Network Is Requisite for RAS Oncogene-Driven Non-Small Cell Lung Cancer

(2012) Madhu S. Kumar et al.   CELL

Signaling from the Sympathetic Nervous System Regulates Hematopoietic Stem Cell Emergence during Embryogenesis

(2012) Simon R. Fitch et al.   Cell Stem Cell

GADD45G Functions in Male Sex Determination by Promoting p38 Signaling and Sry Expression

(2012) Mathias S. Gierl et al.   DEVELOPMENTAL CELL

PRC2 directly methylates GATA4 and represses its transcriptional activity

(2012) A. He et al.   GENES & DEVELOPMENT

Gata6is required for complete acinar differentiation and maintenance of the exocrine pancreas in adult mice

(2012) Paola Martinelli et al.   GUT

Histone acetylation and DNA demethylation of T cells result in an anaplastic large cell lymphoma-like phenotype

(2012) M. Joosten et al.   HAEMATOLOGICA

Mutational spectrum of the GATA5 gene associated with familial atrial fibrillation

(2012) Yi-Qing Yang et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Prevalence and spectrum of GATA5 mutations associated with congenital heart disease

(2012) Jin-Qi Jiang et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

GATA2 mutations are frequent in intermediate-risk karyotype AML with biallelic CEBPA mutations and are associated with favorable prognosis

(2012) A Fasan et al.   LEUKEMIA

Heart repair by reprogramming non-myocytes with cardiac transcription factors

(2012) Kunhua Song et al.   NATURE

In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes

(2012) Li Qian et al.   NATURE

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

(2012) Jinghui Zhang et al.   NATURE

Association analyses identify multiple new lung cancer susceptibility loci and their interactions with smoking in the Chinese population

(2012) Jing Dong et al.   NATURE GENETICS

Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies

(2012) E. H. Bresnick et al.   NUCLEIC ACIDS RESEARCH

Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21

(2012) A. Roy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trisomy 21-associated defects in human primitive hematopoiesis revealed through induced pluripotent stem cells

(2012) S. T. Chou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Altered hematopoiesis in trisomy 21 as revealed through in vitro differentiation of isogenic human pluripotent cells

(2012) G. A. MacLean et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nephric duct insertion is a crucial step in urinary tract maturation that is regulated by a Gata3-Raldh2-Ret molecular network in mice

(2011) I. Chia et al.   DEVELOPMENT

Evaluation of the Methylation Status of Tumour Suppressor Genes for Predicting Bacillus Calmette-Guérin Response in Patients With T1G3 High-Risk Bladder Tumours

(2011) Miriam Agundez et al.   EUROPEAN UROLOGY

GATA Factors Regulate Proliferation, Differentiation, and Gene Expression in Small Intestine of Mature Mice

(2011) Eva Beuling et al.   GASTROENTEROLOGY

Loss of Gata5 in mice leads to bicuspid aortic valve

(2011) Brigitte Laforest et al.   JOURNAL OF CLINICAL INVESTIGATION

A GATA4-regulated tumor suppressor network represses formation of malignant human astrocytomas

(2011) Sameer Agnihotri et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Gata2 Is Required for Migration and Differentiation of Retinorecipient Neurons in the Superior Colliculus

(2011) R. T. Willett et al.   JOURNAL OF NEUROSCIENCE

Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors

(2011) Pengyu Huang et al.   NATURE

GATA2 mutations lead to MDS and AML

(2011) R. Katherine Hyde et al.   NATURE GENETICS

Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia

(2011) Christopher N Hahn et al.   NATURE GENETICS

Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes

(2011) J. M. Lamonica et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Serine 105 phosphorylation of transcription factor GATA4 is necessary for stress-induced cardiac hypertrophy in vivo

(2011) J. H. van Berlo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss-of-function mutation in GATA4 causes anomalies of human testicular development

(2011) D. Lourenco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hopx and Hdac2 Interact to Modulate Gata4 Acetylation and Embryonic Cardiac Myocyte Proliferation

(2010) Chinmay M. Trivedi et al.   DEVELOPMENTAL CELL

Characterization and In Vivo Pharmacological Rescue of a Wnt2-Gata6 Pathway Required for Cardiac Inflow Tract Development

(2010) Ying Tian et al.   DEVELOPMENTAL CELL

Conditional Gata4 deletion in mice induces bile acid absorption in the proximal small intestine

(2010) E. Beuling et al.   GUT

From the cradle to the grave: activities of GATA-3 throughout T-cell development and differentiation

(2010) Tomonori Hosoya et al.   IMMUNOLOGICAL REVIEWS

Cyclin-dependent Kinase-9 Is a Component of the p300/GATA4 Complex Required for Phenylephrine-induced Hypertrophy in Cardiomyocytes

(2010) Yoichi Sunagawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gata3-deficient mice develop parathyroid abnormalities due to dysregulation of the parathyroid-specific transcription factor Gcm2

(2010) Irina V. Grigorieva et al.   JOURNAL OF CLINICAL INVESTIGATION

The Gata3 Transcription Factor Is Required for the Survival of Embryonic and Adult Sympathetic Neurons

(2010) K. Tsarovina et al.   JOURNAL OF NEUROSCIENCE

SUMO-Specific Protease 2 Is Essential for Suppression of Polycomb Group Protein-Mediated Gene Silencing during Embryonic Development

(2010) Xunlei Kang et al.   MOLECULAR CELL

Loss of type III transforming growth factor-β receptor expression is due to methylation silencing of the transcription factor GATA3 in renal cell carcinoma

(2010) S J Cooper et al.   ONCOGENE

Methylation ofGATA-4andGATA-5and development of sporadic gastric carcinomas

(2010) Xian-Zi Wen   WORLD JOURNAL OF GASTROENTEROLOGY

Mutational spectrum at GATA1 provides insights into mutagenesis and leukemogenesis in Down syndrome

(2009) D. C. Cabelof et al.   BLOOD

Acute megakaryoblastic leukaemia (AMKL) and transient myeloproliferative disorder (TMD) in Down syndrome: a multi-step model of myeloid leukaemogenesis

(2009) Anindita Roy et al.   BRITISH JOURNAL OF HAEMATOLOGY

CDK Inhibitor p18INK4c Is a Downstream Target of GATA3 and Restrains Mammary Luminal Progenitor Cell Proliferation and Tumorigenesis

(2009) Xin-Hai Pei et al.   CANCER CELL

GATA4 and GATA5 are Potential Tumor Suppressors and Biomarkers in Colorectal Cancer

(2009) D. M.E.I. Hellebrekers et al.   CLINICAL CANCER RESEARCH

Gata4andGata5Cooperatively Regulate Cardiac Myocyte Proliferation in Mice

(2009) Manvendra K. Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of GATA6 Leads to Nuclear Deformation and Aneuploidy in Ovarian Cancer

(2009) C. D. Capo-chichi et al.   MOLECULAR AND CELLULAR BIOLOGY

GATA3 inhibits breast cancer growth and pulmonary breast cancer metastasis

(2009) A B Dydensborg et al.   ONCOGENE

GATA4 is a regulator of astrocyte cell proliferation and apoptosis in the human and murine central nervous system

(2009) S Agnihotri et al.   ONCOGENE

GATA6 mutations cause human cardiac outflow tract defects by disrupting semaphorin-plexin signaling

(2009) K. Kodo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cochrane Systematic Review of Colorectal Cancer Screening Using the Fecal Occult Blood Test (Hemoccult): An Update

(2008) Paul Hewitson et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

GATA-2 regulates granulocyte-macrophage progenitor cell function

(2008) N. P. Rodrigues et al.   BLOOD

GATA-3 Links Tumor Differentiation and Dissemination in a Luminal Breast Cancer Model

(2008) Hosein Kouros-Mehr et al.   CANCER CELL

Gata2 is a tissue-specific post-mitotic selector gene for midbrain GABAergic neurons

(2008) K. Kala et al.   DEVELOPMENT

GATA4 Is Essential for Jejunal Function in Mice

(2008) Michele A. Battle et al.   GASTROENTEROLOGY

Identification of p300-targeted Acetylated Residues in GATA4 during Hypertrophic Responses in Cardiac Myocytes

(2008) Tomohide Takaya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA methylation profiles in diffuse large B-cell lymphoma and their relationship to gene expression status

(2008) B L Pike et al.   LEUKEMIA

A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration

(2008) Yuzhen Zhang et al.   NATURE GENETICS

Gain-of-function mutation of GATA-2 in acute myeloid transformation of chronic myeloid leukemia

(2008) S.-J. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA