Medical countermeasures for unwanted CBRN exposures: part II radiological and nuclear threats with review of recent countermeasure patents

Radioprotective Efficacy of Gamma-Tocotrienol in Nonhuman Primates

(2016) Vijay K. Singh et al.   RADIATION RESEARCH

Product Development Under FDA’s Animal Rule

(2016) Theresa Allio   Therapeutic Innovation & Regulatory Science

Colony-stimulating factors for the treatment of the hematopoietic component of the acute radiation syndrome (H-ARS): A review

(2015) Vijay K. Singh et al.   CYTOKINE

Animal models for acute radiation syndrome drug discovery

(2015) Vijay K Singh et al.   Expert Opinion on Drug Discovery

Patents for Toll-like receptor ligands as radiation countermeasures for acute radiation syndrome

(2015) Vijay K Singh et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Use of biomarkers for assessing radiation injury and efficacy of countermeasures

(2015) Vijay K Singh et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

The Effect of Radiation Dose and Variation in Neupogen® Initiation Schedule on the Mitigation of Myelosuppression during the Concomitant GI-ARS and H-ARS in a Nonhuman Primate Model of High-dose Exposure with Marrow Sparing

(2015) Thomas J. MacVittie et al.   HEALTH PHYSICS

Medical Countermeasures for Radiation Exposure and Related Injuries

(2015) Vijay K. Singh et al.   HEALTH PHYSICS

Attenuation of radiation-induced gastrointestinal damage by epidermal growth factor and bone marrow transplantation in mice

(2015) Jaroslav Pejchal et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Combined immunomodulator and antimicrobial therapy eliminates polymicrobial sepsis and modulates cytokine production in combined injured mice

(2015) Thomas B. Elliott et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Novel regenerative peptide TP508 mitigates radiation-induced gastrointestinal damage by activating stem cells and preserving crypt integrity

(2015) Carla Kantara et al.   LABORATORY INVESTIGATION

Pegfilgrastim Improves Survival of Lethally Irradiated Nonhuman Primates

(2015) Kim G. Hankey et al.   RADIATION RESEARCH

Association of Hematological Nadirs and Survival in a Nonhuman Primate Model of Hematopoietic Syndrome of Acute Radiation Syndrome

(2015) Zoya Gluzman-Poltorak et al.   RADIATION RESEARCH

Total Body Irradiation in the “Hematopoietic” Dose Range Induces Substantial Intestinal Injury in Non-Human Primates

(2015) Junru Wang et al.   RADIATION RESEARCH

Mitigation of the Hematopoietic and Gastrointestinal Acute Radiation Syndrome by Octadecenyl Thiophosphate, a Small Molecule Mimic of Lysophosphatidic Acid

(2015) Wenlin Deng et al.   RADIATION RESEARCH

The Toll-Like Receptor 5 Agonist Entolimod Mitigates Lethal Acute Radiation Syndrome in Non-Human Primates

(2015) Vadim I. Krivokrysenko et al.   PLoS One

Recombinant interleukin-12, but not granulocyte-colony stimulating factor, improves survival in lethally irradiated nonhuman primates in the absence of supportive care: Evidence for the development of a frontline radiation medical countermeasure

(2014) Zoya Gluzman-Poltorak et al.   AMERICAN JOURNAL OF HEMATOLOGY

Granulocyte colony-stimulating factor-producing lung cancer and acute respiratory distress syndrome

(2014) Ryota Inokuchi et al.   Clinical Respiratory Journal

Biologics as countermeasures for acute radiation syndrome: where are we now?

(2014) Vijay K Singh et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Radiation countermeasure agents: an update (2011 – 2014)

(2014) Vijay K Singh et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

2013 Dade W. Moeller Lecture

(2014) John E. Moulder   HEALTH PHYSICS

Randomized comparison of single dose of recombinant human IL-12 versus placebo for restoration of hematopoiesis and improved survival in rhesus monkeys exposed to lethal radiation

(2014) Zoya Gluzman-Poltorak et al.   Journal of Hematology & Oncology

Pegylated G-CSF Inhibits Blood Cell Depletion, Increases Platelets, Blocks Splenomegaly, and Improves Survival after Whole-Body Ionizing Irradiation but Not after Irradiation Combined with Burn

(2014) Juliann G. Kiang et al.   Oxidative Medicine and Cellular Longevity

Granulocyte colony-stimulating factor antibody abrogates radioprotective efficacy of gamma-tocotrienol, a promising radiation countermeasure

(2013) Shilpa Kulkarni et al.   CYTOKINE

Survival Efficacy of the PEGylated G-CSFs Maxy-G34 and Neulasta in a Mouse Model of Lethal H-ARS, and Residual Bone Marrow Damage in Treated Survivors

(2013) Hui Lin Chua et al.   HEALTH PHYSICS

The Gottingen Minipig Is a Model of the Hematopoietic Acute Radiation Syndrome: G-Colony Stimulating Factor Stimulates Hematopoiesis and Enhances Survival From Lethal Total-Body γ-Irradiation

(2013) Maria Moroni et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Vitamin E: tocopherols and tocotrienols as potential radiation countermeasures

(2013) Vijay K. Singh et al.   JOURNAL OF RADIATION RESEARCH

Anti-ceramide antibody prevents the radiation gastrointestinal syndrome in mice

(2012) Jimmy Rotolo et al.   JOURNAL OF CLINICAL INVESTIGATION

HemaMax™, a Recombinant Human Interleukin-12, Is a Potent Mitigator of Acute Radiation Injury in Mice and Non-Human Primates

(2012) Lena A. Basile et al.   PLoS One

Pegfilgrastim Administered in an Abbreviated Schedule, Significantly Improved Neutrophil Recovery after High-Dose Radiation-Induced Myelosuppression in Rhesus Macaques

(2012) A. M. Farese et al.   RADIATION RESEARCH

Filgrastim Improves Survival in Lethally Irradiated Nonhuman Primates

(2012) Ann M. Farese et al.   RADIATION RESEARCH

A review of radiation countermeasure work ongoing at the Armed Forces Radiobiology Research Institute

(2011) Vijay K. Singh et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Radiation Injury After a Nuclear Detonation: Medical Consequences and the Need for Scarce Resources Allocation

(2011) Andrea L. DiCarlo et al.   Disaster Medicine and Public Health Preparedness

Regulation of Ceramide Synthase-Mediated Crypt Epithelium Apoptosis by DNA Damage Repair Enzymes

(2010) J. A. Rotolo et al.   CANCER RESEARCH

RADIATION COMBINED INJURY: OVERVIEW OF NIAID RESEARCH

(2010) Andrea L. DiCarlo et al.   HEALTH PHYSICS

Experimental Research on the Management of Combined Radiation-Burn Injury in China

(2010) Xin-Ze Ran et al.   RADIATION RESEARCH

Docking and 3D QSAR studies of protoporphyrinogen oxidase inhibitor 3H-pyrazolo[3,4-d][1,2,3]triazin-4-one derivatives

(2009) Kunal Roy et al.   JOURNAL OF MOLECULAR MODELING

Timing of Lethality From Gastrointestinal Syndrome in Mice Revisited

(2008) Jimmy A. Rotolo et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS