The Toll-Like Receptor 5 Agonist Entolimod Mitigates Lethal Acute Radiation Syndrome in Non-Human Primates

Colony-stimulating factors for the treatment of the hematopoietic component of the acute radiation syndrome (H-ARS): A review

(2015) Vijay K. Singh et al.   CYTOKINE

Toll-like receptor-5 agonist Entolimod broadens the therapeutic window of 5-fluorouracil by reducing its toxicity to normal tissues in mice

(2015) Bojidar M. Kojouharov et al.   Oncotarget

Evaluation of Toll-like, chemokine, and integrin receptors on monocytes and neutrophils from peripheral blood of septic patients and their correlation with clinical outcomes

(2014) S.C. Silva et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Radiation countermeasure agents: an update (2011 – 2014)

(2014) Vijay K Singh et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Randomized comparison of single dose of recombinant human IL-12 versus placebo for restoration of hematopoiesis and improved survival in rhesus monkeys exposed to lethal radiation

(2014) Zoya Gluzman-Poltorak et al.   Journal of Hematology & Oncology

Flagellin Treatment Protects against Chemicals, Bacteria, Viruses, and Radiation

(2014) M. Vijay-Kumar et al.   JOURNAL OF IMMUNOLOGY

TLR Expression on Neutrophils at the Pulmonary Site of Infection: TLR1/TLR2-Mediated Up-Regulation of TLR5 Expression in Cystic Fibrosis Lung Disease

(2014) B. Koller et al.   JOURNAL OF IMMUNOLOGY

A Flagellin-Derived Toll-Like Receptor 5 Agonist Stimulates Cytotoxic Lymphocyte-Mediated Tumor Immunity

(2014) Nicholas D. Leigh et al.   PLoS One

The effect of gamma radiation on the lipid profile of irradiated red blood cells

(2013) Grazielle Aparecida Silva Maia et al.   ANNALS OF HEMATOLOGY

The Role of Platelets and their Microparticles in Rehabilitation of Ischemic Brain Tissue

(2013) Yael Hayon et al.   CNS & Neurological Disorders-Drug Targets

The Ability of Filgrastim to Mitigate Mortality Following LD50/60 Total-body Irradiation Is Administration Time-Dependent

(2013) Ann M. Farese et al.   HEALTH PHYSICS

Linking the Human Response to Unplanned Radiation and Treatment to the Nonhuman Primate Response to Controlled Radiation and Treatment

(2013) Harald Dörr et al.   HEALTH PHYSICS

Central role of liver in anticancer and radioprotective activities of Toll-like receptor 5 agonist

(2013) L. G. Burdelya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Flagellin Administration Protects Respiratory Tract from Burkholderia cepacia Infection

(2012) Ayaid Khadem Zgair   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Prevention and Mitigation of Acute Radiation Syndrome in Mice by Synthetic Lipopeptide Agonists of Toll-Like Receptor 2 (TLR2)

(2012) Alexander N. Shakhov et al.   PLoS One

HemaMax™, a Recombinant Human Interleukin-12, Is a Potent Mitigator of Acute Radiation Injury in Mice and Non-Human Primates

(2012) Lena A. Basile et al.   PLoS One

CBLB613: A TLR 2/6 Agonist, Natural Lipopeptide ofMycoplasma arginini, as a Novel Radiation Countermeasure

(2012) Vijay K. Singh et al.   RADIATION RESEARCH

Filgrastim Improves Survival in Lethally Irradiated Nonhuman Primates

(2012) Ann M. Farese et al.   RADIATION RESEARCH

Regulation and Functions of the IL-10 Family of Cytokines in Inflammation and Disease

(2011) Wenjun Ouyang et al.   Annual Review of Immunology

Acute radiation syndrome caused by accidental radiation exposure - therapeutic principles

(2011) Harald Dörr et al.   BMC Medicine

Radioprotective efficacy of tocopherol succinate is mediated through granulocyte-colony stimulating factor

(2011) Pankaj K. Singh et al.   CYTOKINE

Flagellin administration protects gut mucosal tissue from irradiation-induced apoptosis via MKP-7 activity

(2011) R. M. Jones et al.   GUT

Toll-like Receptor 5 Agonist Protects Mice From Dermatitis and Oral Mucositis Caused by Local Radiation: Implications for Head-and-Neck Cancer Radiotherapy

(2011) Lyudmila G. Burdelya et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Radiation Injury After a Nuclear Detonation: Medical Consequences and the Need for Scarce Resources Allocation

(2011) Andrea L. DiCarlo et al.   Disaster Medicine and Public Health Preparedness

Ketamine Inhibits Transcription Factors Activator Protein 1 and Nuclear Factor-κB, Interleukin-8 Production, as well as CD11b and CD16 Expression: Studies in Human Leukocytes and Leukocytic Cell Lines

(2010) Ingeborg D. Welters et al.   ANESTHESIA AND ANALGESIA

Survivin and IAP proteins in cell-death mechanisms

(2010) Dario C. Altieri   BIOCHEMICAL JOURNAL

New role of the BCL2 family of proteins in the regulation of mitochondrial dynamics

(2010) Stephane G Rolland et al.   CURRENT OPINION IN CELL BIOLOGY

RATIONALE AND RECOMMENDATIONS FOR TREATMENT OF RADIATION INJURY WITH CYTOKINES

(2010) Nicholas Dainiak   HEALTH PHYSICS

Cell type-specific regulation of IL-10 expression in inflammation and disease

(2010) Christian M. Hedrich et al.   IMMUNOLOGIC RESEARCH

Mucosal Administration of Flagellin Protects Mice from Streptococcus pneumoniae Lung Infection

(2010) N. Munoz et al.   INFECTION AND IMMUNITY

Flagellin Stimulates Protective Lung Mucosal Immunity: Role of Cathelicidin-Related Antimicrobial Peptide

(2010) F.-s. Yu et al.   JOURNAL OF IMMUNOLOGY

TLR5 Signaling Stimulates the Innate Production of IL-17 and IL-22 by CD3negCD127+ Immune Cells in Spleen and Mucosa

(2010) L. Van Maele et al.   JOURNAL OF IMMUNOLOGY

The Antimicrobial Heterodimer S100A8/S100A9 (Calprotectin) Is Upregulated by Bacterial Flagellin in Human Epidermal Keratinocytes

(2010) Arby Abtin et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Flagellin delays spontaneous human neutrophil apoptosis

(2010) Gabriela V Salamone et al.   LABORATORY INVESTIGATION

Topical flagellin protects the injured corneas from Pseudomonas aeruginosa infection

(2010) Ashok Kumar et al.   MICROBES AND INFECTION

“Where, O Death, Is Thy Sting?” A Brief Review of Apoptosis Biology

(2010) Andrew H. Wyllie   MOLECULAR NEUROBIOLOGY

TLR5 activation induces secretory interleukin-1 receptor antagonist (sIL-1Ra) and reduces inflammasome-associated tissue damage

(2010) F A Carvalho et al.   Mucosal Immunology

Flagellin-Induced Corneal Antimicrobial Peptide Production and Wound Repair Involve a Novel NF-κB–Independent and EGFR-Dependent Pathway

(2010) Nan Gao et al.   PLoS One

Animal Models for Medical Countermeasures to Radiation Exposure

(2010) Jacqueline P. Williams et al.   RADIATION RESEARCH

Beyond Clotting: The Powers of Platelets

(2010) M. Leslie   SCIENCE

Restoration and reversible expansion of the osteoblastic hematopoietic stem cell niche after marrow radioablation

(2009) M. Dominici et al.   BLOOD

Radioresistant cells expressing TLR5 control the respiratory epithelium's innate immune responses to flagellin

(2009) Laure Janot et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Regulated cell death pathways: New twists in modulation of BCL2 family function

(2009) N. Sasi et al.   MOLECULAR CANCER THERAPEUTICS

Bacterial infection-mediated mucosal signalling induces local renal ischaemia as a defence against sepsis

(2008) Keira Melican et al.   CELLULAR MICROBIOLOGY

Mesenchymal stem cells and their use as cell replacement therapy and disease modelling tool

(2008) J. García-Castro et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

An Agonist of Toll-Like Receptor 5 Has Radioprotective Activity in Mouse and Primate Models

(2008) L. G. Burdelya et al.   SCIENCE

PKB and the mitochondria: AKTing on apoptosis

(2007) Arnaud Parcellier et al.   CELLULAR SIGNALLING