Human Cerebral Perfusion, Oxygen Consumption, and Lactate Production in Response to Hypoxic Exposure

In vivo validation of T2- and susceptibility-based Sv O2 measurements with jugular vein catheterization under hypoxia and hypercapnia

(2019) Xin Miao et al.   MAGNETIC RESONANCE IN MEDICINE

Carbon monoxide inhalation induces headache but no migraine in patients with migraine without aura

(2018) Hashmat Ghanizada et al.   CEPHALALGIA

A Non-invasive Method for Quantifying Cerebral Blood Flow by Hybrid PET/MR

(2018) Tracy Ssali et al.   JOURNAL OF NUCLEAR MEDICINE

Role of the carotid body chemoreceptors in glucose homeostasis and thermoregulation in humans

(2018) Michael J. Joyner et al.   JOURNAL OF PHYSIOLOGY-LONDON

Lactate in the brain: from metabolic end-product to signalling molecule

(2018) Pierre J. Magistretti et al.   NATURE REVIEWS NEUROSCIENCE

Cerebral blood flow, oxygen metabolism, and lactate during hypoxia in patients with obstructive sleep apnea

(2018) M L F Jensen et al.   SLEEP

Cerebral blood flow, oxygen metabolism, and lactate during hypoxia in patients with obstructive sleep apnea

(2018) M L F Jensen et al.   SLEEP

Phase contrast mapping MRI measurements of global cerebral blood flow across different perfusion states – A direct comparison with 15O-H2O positron emission tomography using a hybrid PET/MR system

(2018) Oriol Puig et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Higher physiological vulnerability to hypoxic exposure with advancing age in the human brain

(2018) Mark B Vestergaard et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Brain metabolic sensing and metabolic signaling at the level of an astrocyte

(2017) Nephtali Marina et al.   GLIA

Cerebral metabolism and vascular reactivity during breath-hold and hypoxic challenge in freedivers and healthy controls

(2017) Mark B Vestergaard et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Comparison of global cerebral blood flow measured by phase-contrast mapping MRI with 15 O-H2 O positron emission tomography

(2016) Mark Bitsch Vestergaard et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Aerobic glycolysis during brain activation: adrenergic regulation and influence of norepinephrine on astrocytic metabolism

(2016) Gerald A. Dienel et al.   JOURNAL OF NEUROCHEMISTRY

Oxygen-sensing by arterial chemoreceptors: Mechanisms and medical translation

(2016) José López-Barneo et al.   MOLECULAR ASPECTS OF MEDICINE

L-Lactate protects neurons against excitotoxicity: implication of an ATP-mediated signaling cascade

(2016) P. Jourdain et al.   Scientific Reports

A Lactate-Induced Response to Hypoxia

(2015) Dong Chul Lee et al.   CELL

Cerebral metabolic rate of oxygen in obstructive sleep apnea at rest and in response to breath-hold challenge

(2015) Zachary B Rodgers et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Is L-Lactate a Novel Signaling Molecule in the Brain?

(2015) Valentina Mosienko et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Acute hypoxia increases the cerebral metabolic rate – a magnetic resonance imaging study

(2015) Mark B Vestergaard et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Oxygen Sensing and Homeostasis

(2015) Nanduri R. Prabhakar et al.   PHYSIOLOGY

Lactate Transport and Signaling in the Brain: Potential Therapeutic Targets and Roles in Body—Brain Interaction

(2014) Linda Hildegard Bergersen   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Apoptotic Cell Death Under Hypoxia

(2014) Ataman Sendoel et al.   PHYSIOLOGY

Lactate promotes plasticity gene expression by potentiating NMDA signaling in neurons

(2014) J. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Moderate Hyperventilation during Intravenous Anesthesia Increases Net Cerebral Lactate Efflux

(2013) Frank Grüne et al.   ANESTHESIOLOGY

Lactate Receptor Sites Link Neurotransmission, Neurovascular Coupling, and Brain Energy Metabolism

(2013) K. H. Lauritzen et al.   CEREBRAL CORTEX

Lactate Modulates the Activity of Primary Cortical Neurons through a Receptor-Mediated Pathway

(2013) Luigi Bozzo et al.   PLoS One

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

Hypoxia and exercise provoke both lactate release and lactate oxidation by the human brain

(2012) Morten Overgaard et al.   FASEB JOURNAL

Oxygen Consumption and Blood Flow Coupling in Human Motor Cortex during Intense Finger Tapping: Implication for a Role of Lactate

(2012) Manouchehr S Vafaee et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Temporal dynamics of lactate concentration in the human brain during acute inspiratory hypoxia

(2012) Ashley D. Harris et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Normal glucose uptake in the brain and heart requires an endothelial cell-specific HIF-1 -dependent function

(2012) Y. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial hexokinase II (HKII) and phosphoprotein enriched in astrocytes (PEA15) form a molecular switch governing cellular fate depending on the metabolic state

(2012) P. Mergenthaler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid magnetic resonance measurement of global cerebral metabolic rate of oxygen consumption in humans during rest and hypercapnia

(2011) Varsha Jain et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Accuracy of the cylinder approximation for susceptometric measurement of intravascular oxygen saturation

(2011) Cheng Li et al.   MAGNETIC RESONANCE IN MEDICINE

Hypoxia induces angiogenic factors in brain microvascular endothelial cells

(2011) J. Luo et al.   MICROVASCULAR RESEARCH

FSL

(2011) Mark Jenkinson et al.   NEUROIMAGE

MRI Estimation of Global Brain Oxygen Consumption Rate

(2010) Varsha Jain et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Glial and neuronal control of brain blood flow

(2010) David Attwell et al.   NATURE

Pathological role of hypoxia in Alzheimer's disease

(2009) Xin Zhang et al.   EXPERIMENTAL NEUROLOGY

Cell-cell and intracellular lactate shuttles

(2009) George A. Brooks   JOURNAL OF PHYSIOLOGY-LONDON

Biology of HIF-1α

(2008) A Weidemann et al.   CELL DEATH AND DIFFERENTIATION

Brain metabolism dictates the polarity of astrocyte control over arterioles

(2008) Grant R. J. Gordon et al.   NATURE