Platelet-rich plasma, a source of autologous growth factors and biomimetic scaffold for peripheral nerve regeneration

A new strategy to tackle severe knee osteoarthritis: Combination of intra-articular and intraosseous injections of Platelet Rich Plasma

(2016) Mikel Sánchez et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Advances in peripheral nervous system regenerative therapeutic strategies: A biomaterials approach

(2016) Kyriakos Dalamagkas et al.   Materials Science & Engineering C-Materials for Biological Applications

Alignment of the Fibrin Network Within an Autologous Plasma Clot

(2016) Jan Gessmann et al.   TISSUE ENGINEERING PART C-METHODS

Deciphering the Role of Emx1 in Neurogenesis: A Neuroproteomics Approach

(2016) Firas H. Kobeissy et al.   Frontiers in Molecular Neuroscience

Role of macrophages in Wallerian degeneration and axonal regeneration after peripheral nerve injury

(2015) Peiwen Chen et al.   ACTA NEUROPATHOLOGICA

Peripheral nerve regeneration: Experimental strategies and future perspectives

(2015) Alessandro Faroni et al.   ADVANCED DRUG DELIVERY REVIEWS

Macrophage-Induced Blood Vessels Guide Schwann Cell-Mediated Regeneration of Peripheral Nerves

(2015) Anne-Laure Cattin et al.   CELL

Intranasal PRGF-Endoret enhances neuronal survival and attenuates NF-κB-dependent inflammation process in a mouse model of Parkinson's disease

(2015) Eduardo Anitua et al.   JOURNAL OF CONTROLLED RELEASE

Infiltration of plasma rich in growth factors enhances in vivo angiogenesis and improves reperfusion and tissue remodeling after severe hind limb ischemia

(2015) Eduardo Anitua et al.   JOURNAL OF CONTROLLED RELEASE

Ultrasound-guided plasma rich in growth factors injections and scaffolds hasten motor nerve functional recovery in an ovine model of nerve crush injury

(2015) Mikel Sánchez et al.   Journal of Tissue Engineering and Regenerative Medicine

Platelet-Rich Plasma Promotes Axon Regeneration, Wound Healing, and Pain Reduction: Fact or Fiction

(2015) Damien P. Kuffler   MOLECULAR NEUROBIOLOGY

Single injection of platelet-rich plasma as a novel treatment of carpal tunnel syndrome

(2015) VasileiosS Nikolaou et al.   Neural Regeneration Research

Polymer Scaffolds with Preferential Parallel Grooves Enhance Nerve Regeneration

(2015) Atefeh Mobasseri et al.   TISSUE ENGINEERING PART A

Anti-inflammatory effects of platelet biomaterials in a macrophage cellular model

(2015) T.-Y. Renn et al.   VOX SANGUINIS

Schwann Cells: Development and Role in Nerve Repair

(2015) Kristján R. Jessen et al.   Cold Spring Harbor Perspectives in Biology

Gene therapy and peripheral nerve repair: a perspective

(2015) Stefan A. Hoyng et al.   Frontiers in Molecular Neuroscience

Contrasting the Glial Response to Axon Injury in the Central and Peripheral Nervous Systems

(2014) Amanda Brosius Lutz et al.   DEVELOPMENTAL CELL

A comparative morphological, electrophysiological and functional analysis of axon regeneration through peripheral nerve autografts genetically modified to overexpress BDNF, CNTF, GDNF, NGF, NT3 or VEGF

(2014) Stefan A. Hoyng et al.   EXPERIMENTAL NEUROLOGY

Morphogen and proinflammatory cytokine release kinetics from PRGF-Endoret fibrin scaffolds: Evaluation of the effect of leukocyte inclusion

(2014) E. Anitua et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Nerve Regeneration: Is There an Alternative to Nervous Graft?

(2014) Rodrigo Sabongi et al.   JOURNAL OF RECONSTRUCTIVE MICROSURGERY

Biologic Strategies to Improve Nerve Regeneration after Peripheral Nerve Repair

(2014) Mitra Lavasani et al.   JOURNAL OF RECONSTRUCTIVE MICROSURGERY

An Autologously Generated Platelet-Rich Plasma Suturable Membrane May Enhance Peripheral Nerve Regeneration after Neurorraphy in an Acute Injury Model of Sciatic Nerve Neurotmesis

(2014) Elisabetta Giannessi et al.   JOURNAL OF RECONSTRUCTIVE MICROSURGERY

An inside-out vein graft filled with platelet-rich plasma for repair of a short sciatic nerve defect in rats

(2014) JongWoong Park et al.   Neural Regeneration Research

Plasma rich in growth factors (PRGF-Endoret) reduces neuropathologic hallmarks and improves cognitive functions in an Alzheimer's disease mouse model

(2014) Eduardo Anitua et al.   NEUROBIOLOGY OF AGING

Diminished Schwann Cell Repair Responses Underlie Age-Associated Impaired Axonal Regeneration

(2014) Michio W. Painter et al.   NEURON

An assessment of current techniques for inducing axon regeneration and neurological recovery following peripheral nerve trauma

(2014) Damien P. Kuffler   PROGRESS IN NEUROBIOLOGY

Growth Factors Engineered for Super-Affinity to the Extracellular Matrix Enhance Tissue Healing

(2014) M. M. Martino et al.   SCIENCE

Improved Peripheral Nerve Regeneration Using Acellular Nerve Allografts Loaded with Platelet-Rich Plasma

(2014) Canbin Zheng et al.   TISSUE ENGINEERING PART A

Sculpting the blank slate: How fibrin’s support of vascularization can inspire biomaterial design

(2013) Jacob Ceccarelli et al.   Acta Biomaterialia

Fibrin-based biomaterials: Modulation of macroscopic properties through rational design at the molecular level

(2013) Ashley C. Brown et al.   Acta Biomaterialia

Comparison and characterization of multiple biomaterial conduits for peripheral nerve repair

(2013) William T. Daly et al.   BIOMATERIALS

Engineering peripheral nerve repair

(2013) Laura M Marquardt et al.   CURRENT OPINION IN BIOTECHNOLOGY

Cell therapy with bone marrow stromal cells after intracerebral hemorrhage: impact of platelet-rich plasma scaffolds

(2013) Jesus Vaquero et al.   CYTOTHERAPY

Combined treatment with platelet-rich plasma and brain-derived neurotrophic factor-overexpressing bone marrow stromal cells supports axonal remyelination in a rat spinal cord hemi-section model

(2013) Tengfei Zhao et al.   CYTOTHERAPY

Gene therapy approaches to enhance regeneration of the injured peripheral nerve

(2013) Fred de Winter et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Sensory improvement of leprosy peripheral neuropathy in patients treated with perineural injection of platelet-rich plasma

(2013) Sukma Anjayani et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Peripheral Nerve Repair and Reconstruction

(2013) Justin W. Griffin et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Nerve Repair by Means of Tubulization: Past, Present, Future

(2013) P. Konofaos et al.   JOURNAL OF RECONSTRUCTIVE MICROSURGERY

High-throughput proteomic characterization of plasma rich in growth factors (PRGF-Endoret)-derived fibrin clot interactome

(2013) Eduardo Anitua et al.   Journal of Tissue Engineering and Regenerative Medicine

Effect of platelet-rich plasma (PRP) concentration on proliferation, neurotrophic function and migration of Schwann cellsin vitro

(2013) Canbin Zheng et al.   Journal of Tissue Engineering and Regenerative Medicine

Ultrasound-guided platelet-rich plasma injections for the treatment of common peroneal nerve palsy associated with multiple ligament injuries of the knee

(2013) M. Sánchez et al.   KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY

Effect of platelet rich plasma and platelet rich fibrin on sciatic nerve regeneration in a rat model

(2013) Martina Lichtenfels et al.   MICROSURGERY

Platelet-rich plasma limits the nerve injury caused by 10% dextrose in the rabbit median nerve

(2013) Gi-Young Park et al.   MUSCLE & NERVE

Advances in peripheral nerve regeneration

(2013) Jami Scheib et al.   Nature Reviews Neurology

Intranasal Delivery of Plasma and Platelet Growth Factors Using PRGF-Endoret System Enhances Neurogenesis in a Mouse Model of Alzheimer’s Disease

(2013) Eduardo Anitua et al.   PLoS One

Heparin-binding domain of fibrin(ogen) binds growth factors and promotes tissue repair when incorporated within a synthetic matrix

(2013) M. M. Martino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endogenous morphogens and fibrin bioscaffolds for stem cell therapeutics

(2013) Eduardo Anitua et al.   TRENDS IN BIOTECHNOLOGY

Resident mesenchymal cells and fibrosis

(2012) Nicol Hutchison et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Effect of modulating macrophage phenotype on peripheral nerve repair

(2012) Nassir Mokarram et al.   BIOMATERIALS

The protection of MSCs from apoptosis in nerve regeneration by TGFβ1 through reducing inflammation and promoting VEGF-dependent angiogenesis

(2012) Hailang Luo et al.   BIOMATERIALS

Long-Distance Growth and Connectivity of Neural Stem Cells after Severe Spinal Cord Injury

(2012) Paul Lu et al.   CELL

Repeat Operation for Treatment of Persistent Pudendal Nerve Entrapment After Pudendal Neurolysis

(2012) Michael Hibner et al.   Journal of Minimally Invasive Gynecology

The Neuroprotective Effect of Platelet‐rich Plasma on Erectile Function in Bilateral Cavernous Nerve Injury Rat Model

(2012) Chien‐Chih Wu et al.   Journal of Sexual Medicine

The challenges and beauty of peripheral nerve regrowth

(2012) Douglas W. Zochodne   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

Regenerative cell injection in denervated muscle reduces atrophy and enhances recovery following nerve repair

(2012) Dominique Schaakxs et al.   MUSCLE & NERVE

Platelet-Derived Growth Factors-BB and Fibroblast Growth Factors-Base Induced Proliferation of Schwann Cells in a 3D Environment

(2012) Huajun Jiang et al.   NEUROCHEMICAL RESEARCH

c-Jun Reprograms Schwann Cells of Injured Nerves to Generate a Repair Cell Essential for Regeneration

(2012) Peter J. Arthur-Farraj et al.   NEURON

Human platelet-rich plasma promotes axon growth in brain–spinal cord coculture

(2012) Michiko Takeuchi et al.   NEUROREPORT

Specificity of peripheral nerve regeneration: Interactions at the axon level

(2012) Ilary Allodi et al.   PROGRESS IN NEUROBIOLOGY

Perspectives in regeneration and tissue engineering of peripheral nerves

(2011) Stefania Raimondo et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

Wallerian degeneration and peripheral nerve conditions for both axonal regeneration and neuropathic pain induction

(2011) Petr Dubový   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

Synergistic Effects of Bone Mesenchymal Stem Cells and Chondroitinase ABC on Nerve Regeneration After Acellular Nerve Allograft in Rats

(2011) Ying Wang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Signaling cue presentation and cell delivery to promote nerve regeneration

(2011) Kellin Krick et al.   CURRENT OPINION IN BIOTECHNOLOGY

Accelerating axonal growth promotes motor recovery after peripheral nerve injury in mice

(2011) Chi Him Eddie Ma et al.   JOURNAL OF CLINICAL INVESTIGATION

Perspectives and challenges in regenerative medicine using plasma rich in growth factors

(2011) Eduardo Anitua et al.   JOURNAL OF CONTROLLED RELEASE

Prevention of the β-amyloid peptide-induced inflammatory process by inhibition of double-stranded RNA-dependent protein kinase in primary murine mixed co-cultures

(2011) J Couturier et al.   Journal of Neuroinflammation

The effect of melatonin and platelet gel on sciatic nerve repair: An electrophysiological and stereological study

(2011) SüLeyman Kaplan et al.   MICROSURGERY

Neurological Recovery Across a 12-cm-Long Ulnar Nerve Gap Repaired 3.25 Years Post Trauma

(2011) Damien P. Kuffler et al.   NEUROSURGERY

Next Generation Nerve Guides: Materials, Fabrication, Growth Factors, and Cell Delivery

(2011) Juliet H.A. Bell et al.   TISSUE ENGINEERING PART B-REVIEWS

CYLD regulates keratinocyte differentiation and skin cancer progression in humans

(2011) J P Alameda et al.   Cell Death & Disease

Topography, Cell Response, and Nerve Regeneration

(2010) Diane Hoffman-Kim et al.   Annual Review of Biomedical Engineering

Ligamentization of Tendon Grafts Treated With an Endogenous Preparation Rich in Growth Factors: Gross Morphology and Histology

(2010) Mikel Sánchez et al.   ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY

EphB Signaling Directs Peripheral Nerve Regeneration through Sox2-Dependent Schwann Cell Sorting

(2010) Simona Parrinello et al.   CELL

Cell therapy for spinal cord repair: optimization of biologic scaffolds for survival and neural differentiation of human bone marrow stromal cells

(2010) Mercedes Zurita et al.   CYTOTHERAPY

Effects of insulin-like growth factor–I and platelet-rich plasma on sciatic nerve crush injury in a rat model

(2010) Erhan Emel et al.   JOURNAL OF NEUROSURGERY

Schwann cell delivery of neurotrophic factors for peripheral nerve regeneration

(2010) Srinivas Madduri et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

Effect of neural-induced mesenchymal stem cells and platelet-rich plasma on facial nerve regeneration in an acute nerve injury model

(2010) Hyong-Ho Cho et al.   LARYNGOSCOPE

Hepatocyte Growth Factor Modulates Interleukin-6 Production in Bone Marrow Derived Macrophages: Implications for Inflammatory Mediated Diseases

(2010) Gina M. Coudriet et al.   PLoS One

Repairing injured peripheral nerves: Bridging the gap

(2010) Ronald Deumens et al.   PROGRESS IN NEUROBIOLOGY

The effect of platelet-rich plasma on the neovascularization of surgically created equine superficial digital flexor tendon lesions

(2010) G. Bosch et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

Sustained Growth Factor Delivery Promotes Axonal Regeneration in Long Gap Peripheral Nerve Repair

(2010) Lauren E. Kokai et al.   TISSUE ENGINEERING PART A

Repair and Neurorehabilitation Strategies for Spinal Cord Injury

(2009) Robert L. Ruff et al.   Annals of the New York Academy of Sciences

Thin-film enhanced nerve guidance channels for peripheral nerve repair

(2009) Isaac P. Clements et al.   BIOMATERIALS

Management of nerve gaps: Autografts, allografts, nerve transfers, and end-to-side neurorrhaphy

(2009) Wilson Z. Ray et al.   EXPERIMENTAL NEUROLOGY

The effect of laminin peptide gradient in enzymatically cross-linked collagen scaffolds on neurite growth

(2009) Li Yao et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Adipose-derived stem cells enhance peripheral nerve regeneration

(2009) P.G. di Summa et al.   Journal of Plastic Reconstructive and Aesthetic Surgery

Functional muscle regeneration with combined delivery of angiogenesis and myogenesis factors

(2009) Cristina Borselli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Platelet-Rich Therapies in the Treatment of Orthopaedic Sport Injuries

(2009) Mikel Sánchez et al.   SPORTS MEDICINE

Affinity-based release of glial-derived neurotrophic factor from fibrin matrices enhances sciatic nerve regeneration

(2008) Matthew D. Wood et al.   Acta Biomaterialia

Platelet-rich plasma accelerated surgical angio-genesis in vascular-implanted necrotic bone: An experimental study in rabbits

(2008) Kazunori Yokota et al.   Acta Orthopaedica

Interactions between Schwann cells and macrophages in injury and inherited demyelinating disease

(2008) Rudolf Martini et al.   GLIA

Schwann Cell Strip for Peripheral Nerve Repair

(2008) D. F. KALBERMATTEN et al.   Journal of Hand Surgery-European Volume

Effect of Platelet-Rich Plasma on Peripheral Nerve Regeneration

(2008) Yakup Sariguney et al.   JOURNAL OF RECONSTRUCTIVE MICROSURGERY

Fibrin gels and their clinical and bioengineering applications

(2008) P. A Janmey et al.   Journal of the Royal Society Interface

Neuronal death after peripheral nerve injury and experimental strategies for neuroprotection

(2008) Andrew M. Hart et al.   NEUROLOGICAL RESEARCH