Loss of Y chromosome at the interface between aging and Alzheimer’s disease

Increased stem cell proliferation in atherosclerosis accelerates clonal hematopoiesis

(2021) Alexander Heyde et al.   CELL

Immune cells lacking Y chromosome show dysregulation of autosomal gene expression

(2021) Jan P. Dumanski et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Decoding and rejuvenating human ageing genomes: Lessons from mosaic chromosomal alterations

(2021) Xueqin Dai et al.   AGEING RESEARCH REVIEWS

Loss of Y chromosome: An emerging next-generation biomarker for disease prediction and early detection?

(2021) Xihan Guo et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection

(2021) Seyedeh M. Zekavat et al.   NATURE MEDICINE

Leukocytes with chromosome Y loss have reduced abundance of the cell surface immunoprotein CD99

(2021) Jonas Mattisson et al.   Scientific Reports

Mosaic loss of human Y chromosome: what, how and why

(2020) Xihan Guo et al.   HUMAN GENETICS

Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer’s disease

(2020) David Gate et al.   NATURE

Do infections have a role in the pathogenesis of Alzheimer disease?

(2020) Ruth F. Itzhaki et al.   Nature Reviews Neurology

A second X chromosome contributes to resilience in a mouse model of Alzheimer’s disease

(2020) Emily J. Davis et al.   Science Translational Medicine

Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk

(2019) Iris E. Jansen et al.   NATURE GENETICS

Genetic predisposition to mosaic Y chromosome loss in blood

(2019) Deborah J. Thompson et al.   NATURE

Clonal hematopoiesis in human aging and disease

(2019) Siddhartha Jaiswal et al.   SCIENCE

Mosaic Loss of Chromosome Y in Blood Is Associated with Alzheimer Disease

(2016) Jan P. Dumanski et al.   AMERICAN JOURNAL OF HUMAN GENETICS