GABA-receptive microglia selectively sculpt developing inhibitory circuits

Inhibition of Microglial TGFβ Signaling Increases Expression of Mrc1

(2020) Alexander von Ehr et al.   Frontiers in Cellular Neuroscience

Microglial Remodeling of the Extracellular Matrix Promotes Synapse Plasticity

(2020) Phi T. Nguyen et al.   CELL

Negative feedback control of neuronal activity by microglia

(2020) Ana Badimon et al.   NATURE

Viral manipulation of functionally distinct interneurons in mice, non-human primates and humans

(2020) Douglas Vormstein-Schneider et al.   NATURE NEUROSCIENCE

Sensory Experience Engages Microglia to Shape Neural Connectivity through a Non-Phagocytic Mechanism

(2020) Lucas Cheadle et al.   NEURON

Microglia elimination increases neural circuit connectivity and activity in adult mouse cortex

(2020) Yong-Jun Liu et al.   JOURNAL OF NEUROSCIENCE

Distinct molecular programs regulate synapse specificity in cortical inhibitory circuits

(2019) Emilia Favuzzi et al.   SCIENCE

Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution

(2019) Takahiro Masuda et al.   NATURE

The single-cell transcriptional landscape of mammalian organogenesis

(2019) Junyue Cao et al.   NATURE

Hyperactivity with Disrupted Attention by Activation of an Astrocyte Synaptogenic Cue

(2019) Jun Nagai et al.   CELL

Excitation-inhibition balance as a framework for investigating mechanisms in neuropsychiatric disorders

(2019) Vikaas S. Sohal et al.   MOLECULAR PSYCHIATRY

A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment

(2019) Hannah Van Hove et al.   NATURE NEUROSCIENCE

Neuron-Glia Signaling in Synapse Elimination

(2019) Daniel K. Wilton et al.   Annual Review of Neuroscience

GABAergic‐astrocyte signaling: A refinement of inhibitory brain networks

(2019) Sara Mederos et al.   GLIA

Biphasic Impact of Prenatal Inflammation and Macrophage Depletion on the Wiring of Neocortical Inhibitory Circuits

(2019) Morgane Sonia Thion et al.   Cell Reports

Microglia in Brain Development, Homeostasis, and Neurodegeneration

(2019) Christopher J. Bohlen et al.   Annual Review of Genetics

Neuronal network activity controls microglial process surveillance in awake mice via norepinephrine signaling

(2019) Yong U. Liu et al.   NATURE NEUROSCIENCE

Noradrenergic signaling in the wakeful state inhibits microglial surveillance and synaptic plasticity in the mouse visual cortex

(2019) Rianne D. Stowell et al.   NATURE NEUROSCIENCE

Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer’s disease model

(2019) Elizabeth Spangenberg et al.   Nature Communications

Microglial depletion prevents extracellular matrix changes and striatal volume reduction in a model of Huntington's disease

(2019) Joshua D Crapser et al.   BRAIN

Orchestrating single-cell analysis with Bioconductor

(2019) Robert A. Amezquita et al.   NATURE METHODS

Microglia monitor and protect neuronal function through specialized somatic purinergic junctions

(2019) Csaba Cserép et al.   SCIENCE

The Striatum Organizes 3D Behavior via Moment-to-Moment Action Selection

(2018) Jeffrey E. Markowitz et al.   CELL

Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration

(2018) Aleksandra Deczkowska et al.   CELL

Molecular diversity underlying cortical excitatory and inhibitory synapse development

(2018) Emilia Favuzzi et al.   CURRENT OPINION IN NEUROBIOLOGY

The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity

(2018) Fabia Filipello et al.   IMMUNITY

Fluorescent Proteins for Investigating Biological Events in Acidic Environments

(2018) Hajime Shinoda et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Molecular Diversity and Specializations among the Cells of the Adult Mouse Brain

(2018) Arpiar Saunders et al.   CELL

Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes

(2018) Timothy R. Hammond et al.   IMMUNITY

Rbfox1 Mediates Cell-type-Specific Splicing in Cortical Interneurons

(2018) Brie Wamsley et al.   NEURON

Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing

(2018) Qingyun Li et al.   NEURON

Molecular, spatial, and functional single-cell profiling of the hypothalamic preoptic region

(2018) Jeffrey R. Moffitt et al.   SCIENCE

Microglia and early brain development: An intimate journey

(2018) Morgane S. Thion et al.   SCIENCE

Complement 3a receptor in dorsal horn microglia mediates pronociceptive neuropeptide signaling

(2017) Suzanne Doolen et al.   GLIA

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

(2017) Susanne Krasemann et al.   IMMUNITY

Errant gardeners: glial-cell-dependent synaptic pruning and neurodevelopmental disorders

(2017) Urte Neniskyte et al.   NATURE REVIEWS NEUROSCIENCE

Activity-Dependent Gating of Parvalbumin Interneuron Function by the Perineuronal Net Protein Brevican

(2017) Emilia Favuzzi et al.   NEURON

Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation

(2016) Hansen Lui et al.   CELL

UniProt: the universal protein knowledgebase

(2016)   NUCLEIC ACIDS RESEARCH

De novo synaptogenesis induced by GABA in the developing mouse cortex

(2016) Won Chan Oh et al.   SCIENCE

Microglia development follows a stepwise program to regulate brain homeostasis

(2016) O. Matcovitch-Natan et al.   SCIENCE

The Emerging Picture of Autism Spectrum Disorder: Genetics and Pathology

(2015) Jason A. Chen et al.   Annual Review of Pathology-Mechanisms of Disease

Receptors, Ion Channels, and Signaling Mechanisms Underlying Microglial Dynamics

(2015) Christian Madry et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spatial reconstruction of single-cell gene expression data

(2015) Rahul Satija et al.   NATURE BIOTECHNOLOGY

The GABAA Receptor as a Therapeutic Target for Neurodevelopmental Disorders

(2015) Sien Braat et al.   NEURON

Mapping Sub-Second Structure in Mouse Behavior

(2015) Alexander B. Wiltschko et al.   NEURON

Spatially resolved, highly multiplexed RNA profiling in single cells

(2015) K. H. Chen et al.   SCIENCE

Microglial displacement of inhibitory synapses provides neuroprotection in the adult brain

(2014) Zhihong Chen et al.   Nature Communications

Microglia Modulate Wiring of the Embryonic Forebrain

(2014) Paola Squarzoni et al.   Cell Reports

viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia

(2013) El-ad David Amir et al.   NATURE BIOTECHNOLOGY

Emerging neurotrophic role of GABAB receptors in neuronal circuit development

(2013) Jean-Luc Gaiarsa et al.   Frontiers in Cellular Neuroscience

Functional role of ambient GABA in refining neuronal circuits early in postnatal development

(2013) Giada Cellot et al.   Frontiers in Neural Circuits

Comparing development of synaptic proteins in rat visual, somatosensory, and frontal cortex

(2013) Joshua G. A. Pinto et al.   Frontiers in Neural Circuits

Reduced GABA Concentration in Attention-Deficit/Hyperactivity Disorder

(2012) Richard A. E. Edden et al.   ARCHIVES OF GENERAL PSYCHIATRY

GABA Signaling Promotes Synapse Elimination and Axon Pruning in Developing Cortical Inhibitory Interneurons

(2012) X. Wu et al.   JOURNAL OF NEUROSCIENCE

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

(2012) Linda Madisen et al.   NATURE NEUROSCIENCE

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

A review of fronto-striatal and fronto-cortical brain abnormalities in children and adults with Attention Deficit Hyperactivity Disorder (ADHD) and new evidence for dysfunction in adults with ADHD during motivation and attention

(2011) Ana Cubillo et al.   CORTEX

The splicing regulator Rbfox1 (A2BP1) controls neuronal excitation in the mammalian brain

(2011) Lauren T Gehman et al.   NATURE GENETICS

Motor cortex inhibition: A marker of ADHD behavior and motor development in children

(2011) D. L. Gilbert et al.   NEUROLOGY

Microglial Morphology and Dynamic Behavior Is Regulated by Ionotropic Glutamatergic and GABAergic Neurotransmission

(2011) Aurora M. Fontainhas et al.   PLoS One

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

Microglial Physiology: Unique Stimuli, Specialized Responses

(2009) Richard M. Ransohoff et al.   Annual Review of Immunology

Defining the role of GABA in cortical development

(2009) Doris D. Wang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Gating multiple signals through detailed balance of excitation and inhibition in spiking networks

(2009) Tim P Vogels et al.   NATURE NEUROSCIENCE

GFP-like Proteins Stably Accumulate in Lysosomes

(2008) Hiroyuki Katayama et al.   CELL STRUCTURE AND FUNCTION