Viral manipulation of functionally distinct interneurons in mice, non-human primates and humans

Functional Access to Neuron Subclasses in Rodent and Primate Forebrain

(2019) Preeti Mehta et al.   Cell Reports

Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates and humans

(2019) Josephine Jüttner et al.   NATURE NEUROSCIENCE

Vasoactive intestinal peptide-expressing interneurons are impaired in a mouse model of Dravet syndrome

(2019) Kevin M Goff et al.   eLife

Conserved cell types with divergent features in human versus mouse cortex

(2019) Rebecca D. Hodge et al.   NATURE

Optogenetic and chemogenetic therapies for epilepsy

(2019) Matthew C. Walker et al.   NEUROPHARMACOLOGY

CiiiDER: A tool for predicting and analysing transcription factor binding sites

(2019) Linden J. Gearing et al.   PLoS One

Mapping human cell phenotypes to genotypes with single-cell genomics

(2019) J. Gray Camp et al.   SCIENCE

A scalable platform for the development of cell-type-specific viral drivers

(2019) Sinisa Hrvatin et al.   eLife

Viral Strategies for Targeting the Central and Peripheral Nervous Systems

(2018) Claire N. Bedbrook et al.   Annual Review of Neuroscience

Ultraconserved Enhancers Are Required for Normal Development

(2018) Diane E. Dickel et al.   CELL

A Suite of Transgenic Driver and Reporter Mouse Lines with Enhanced Brain-Cell-Type Targeting and Functionality

(2018) Tanya L. Daigle et al.   CELL

Marked Diversity of Unique Cortical Enhancers Enables Neuron-Specific Tools by Enhancer-Driven Gene Expression

(2018) Stefan Blankvoort et al.   CURRENT BIOLOGY

Genetic identification of brain cell types underlying schizophrenia

(2018) Nathan G. Skene et al.   NATURE GENETICS

Preclinical Animal Models for Dravet Syndrome: Seizure Phenotypes, Comorbidities and Drug Screening

(2018) Aliesha Griffin et al.   Frontiers in Pharmacology

Molecular Diversity and Specializations among the Cells of the Adult Mouse Brain

(2018) Arpiar Saunders et al.   CELL

A Transient Developmental Window of Fast-Spiking Interneuron Dysfunction in a Mouse Model of Dravet Syndrome

(2018) Morgana Favero et al.   JOURNAL OF NEUROSCIENCE

Transcriptomic and morphophysiological evidence for a specialized human cortical GABAergic cell type

(2018) Eszter Boldog et al.   NATURE NEUROSCIENCE

Gene therapy for neurological disorders: progress and prospects

(2018) Benjamin E. Deverman et al.   NATURE REVIEWS DRUG DISCOVERY

Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies

(2018)   Nature Communications

Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems

(2017) Ken Y Chan et al.   NATURE NEUROSCIENCE

Adult mouse cortical cell taxonomy revealed by single cell transcriptomics

(2016) Bosiljka Tasic et al.   NATURE NEUROSCIENCE

A viral strategy for targeting and manipulating interneurons across vertebrate species

(2016) Jordane Dimidschstein et al.   NATURE NEUROSCIENCE

GABAergic Interneurons in the Neocortex: From Cellular Properties to Circuits

(2016) Robin Tremblay et al.   NEURON

Systematic mapping of functional enhancer–promoter connections with CRISPR interference

(2016) Charles P. Fulco et al.   SCIENCE

rAAV-compatible MiniPromoters for restricted expression in the brain and eye

(2016) Charles N. de Leeuw et al.   Molecular Brain

Disruption of mGluR5 in parvalbumin-positive interneurons induces core features of neurodevelopmental disorders

(2015) S A Barnes et al.   MOLECULAR PSYCHIATRY

Single-cell chromatin accessibility reveals principles of regulatory variation

(2015) Jason D. Buenrostro et al.   NATURE

Epigenomic Signatures of Neuronal Diversity in the Mammalian Brain

(2015) Alisa Mo et al.   NEURON

CEGA—a catalog of conserved elements from genomic alignments

(2015) Aline Dousse et al.   NUCLEIC ACIDS RESEARCH

Multiplex single-cell profiling of chromatin accessibility by combinatorial cellular indexing

(2015) D. A. Cusanovich et al.   SCIENCE

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

An organotypic brain slice preparation from adult patients with temporal lobe epilepsy

(2014) Emmanuel Eugène et al.   JOURNAL OF NEUROSCIENCE METHODS

Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies

(2014)   LANCET NEUROLOGY

An atlas of active enhancers across human cell types and tissues

(2014) Robin Andersson et al.   NATURE

Common variants associated with general and MMR vaccine–related febrile seizures

(2014) Bjarke Feenstra et al.   NATURE GENETICS

Integrative Functional Genomic Analyses Implicate Specific Molecular Pathways and Circuits in Autism

(2013) Neelroop N. Parikshak et al.   CELL

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

Applying tensor-based morphometry to parametric surfaces can improve MRI-based disease diagnosis

(2013) Yalin Wang et al.   NEUROIMAGE

Preferential inactivation of Scn1a in parvalbumin interneurons increases seizure susceptibility

(2012) Stacey B. Dutton et al.   NEUROBIOLOGY OF DISEASE

UCNEbase—a database of ultraconserved non-coding elements and genomic regulatory blocks

(2012) Slavica Dimitrieva et al.   NUCLEIC ACIDS RESEARCH

Measuring the Maturity of the Fast-Spiking Interneuron Transcriptional Program in Autism, Schizophrenia, and Bipolar Disorder

(2012) Michael J. Gandal et al.   PLoS One

Specific deletion of NaV1.1 sodium channels in inhibitory interneurons causes seizures and premature death in a mouse model of Dravet syndrome

(2012) C. S. Cheah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptomic analysis of autistic brain reveals convergent molecular pathology

(2011) Irina Voineagu et al.   NATURE

Neocortical excitation/inhibition balance in information processing and social dysfunction

(2011) Ofer Yizhar et al.   NATURE

The Cell-Intrinsic Requirement of Sox6 for Cortical Interneuron Development

(2009) Renata Batista-Brito et al.   NEURON