Preservation of vision after CaMKII-mediated protection of retinal ganglion cells

Mouse γ-Synuclein Promoter-Mediated Gene Expression and Editing in Mammalian Retinal Ganglion Cells

(2020) Qizhao Wang et al.   JOURNAL OF NEUROSCIENCE

Reprogramming to recover youthful epigenetic information and restore vision

(2020) Yuancheng Lu et al.   NATURE

Using Looming Visual Stimuli to Evaluate Mouse Vision

(2019) Christina C. Koehler et al.   Jove-Journal of Visualized Experiments

Single-Cell Profiles of Retinal Ganglion Cells Differing in Resilience to Injury Reveal Neuroprotective Genes

(2019) Nicholas M. Tran et al.   NEURON

Downregulation of splicing regulator RBFOX1 compromises visual depth perception

(2018) Lei Gu et al.   PLoS One

A midline thalamic circuit determines reactions to visual threat

(2018) Lindsey D. Salay et al.   NATURE

Loss of Shp2 Rescues BDNF/TrkB Signaling and Contributes to Improved Retinal Ganglion Cell Neuroprotection

(2018) Nitin Chitranshi et al.   MOLECULAR THERAPY

Return of function after CNS axon regeneration: Lessons from injury-responsive intrinsically photosensitive and alpha retinal ganglion cells

(2018) Martin Berry et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Reaching the brain: Advances in optic nerve regeneration

(2017) Larry I. Benowitz et al.   EXPERIMENTAL NEUROLOGY

Protecting retinal ganglion cells

(2017) T Z Khatib et al.   EYE

Vitamin B 3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice

(2017) Pete A. Williams et al.   SCIENCE

Regenerating optic pathways from the eye to the brain

(2017) Bireswar Laha et al.   SCIENCE

Neuroprotection in Glaucoma: Animal Models and Clinical Trials

(2017) Mohammadali Almasieh et al.   Annual Review of Vision Science

Rescue of Glaucomatous Neurodegeneration by Differentially Modulating Neuronal Endoplasmic Reticulum Stress Molecules

(2016) L. Yang et al.   JOURNAL OF NEUROSCIENCE

Neural activity promotes long-distance, target-specific regeneration of adult retinal axons

(2016) Jung-Hwan A Lim et al.   NATURE NEUROSCIENCE

Intrinsic Control of Axon Regeneration

(2016) Zhigang He et al.   NEURON

A Magnetic Microbead Occlusion Model to Induce Ocular Hypertension-Dependent Glaucoma in Mice

(2016) Yoko A. Ito et al.   Jove-Journal of Visualized Experiments

Primary open-angle glaucoma

(2016) Robert N. Weinreb et al.   Nature Reviews Disease Primers

CREB-mediated synaptogenesis and neurogenesis is crucial for the role of 5-HT1a receptors in modulating anxiety behaviors

(2016) Jing Zhang et al.   Scientific Reports

Contributions of Retinal Ganglion Cells to Subcortical Visual Processing and Behaviors

(2015) Onkar S. Dhande et al.   Annual Review of Vision Science

γCaMKII Shuttles Ca2+/CaM to the Nucleus to Trigger CREB Phosphorylation and Gene Expression

(2014) Huan Ma et al.   CELL

Global Prevalence of Glaucoma and Projections of Glaucoma Burden through 2040

(2014) Yih-Chung Tham et al.   OPHTHALMOLOGY

Rapid Innate Defensive Responses of Mice to Looming Visual Stimuli

(2013) Melis Yilmaz et al.   CURRENT BIOLOGY

Long-Term Trends in Glaucoma-Related Blindness in Olmsted County, Minnesota

(2013) Mehrdad Malihi et al.   OPHTHALMOLOGY

DLK initiates a transcriptional program that couples apoptotic and regenerative responses to axonal injury

(2013) T. A. Watkins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death

(2013) D. S. Welsbie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Under Pressure: Cellular and Molecular Responses During Glaucoma, a Common Neurodegeneration with Axonopathy

(2012) Robert W. Nickells et al.   Annual Review of Neuroscience

Calcium/Calmodulin-dependent Protein Kinase II (CaMKII) Inhibition Induces Neurotoxicity via Dysregulation of Glutamate/Calcium Signaling and Hyperexcitability

(2012) Nicole M. Ashpole et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Excitotoxicity Downregulates TrkB.FL Signaling and Upregulates the Neuroprotective Truncated TrkB Receptors in Cultured Hippocampal and Striatal Neurons

(2012) J. R. Gomes et al.   JOURNAL OF NEUROSCIENCE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Differential Effects of Unfolded Protein Response Pathways on Axon Injury-Induced Death of Retinal Ganglion Cells

(2012) Yang Hu et al.   NEURON

Critical pathogenic events underlying progression of neurodegeneration in glaucoma

(2012) David J. Calkins   PROGRESS IN RETINAL AND EYE RESEARCH

Excitotoxic neuroprotection and vulnerability with CaMKII inhibition

(2011) Nicole M. Ashpole et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Sustained axon regeneration induced by co-deletion of PTEN and SOCS3

(2011) Fang Sun et al.   NATURE

Visual map development depends on the temporal pattern of binocular activity in mice

(2011) Jiayi Zhang et al.   NATURE NEUROSCIENCE

Potential therapeutic uses of BDNF in neurological and psychiatric disorders

(2011) Alan H. Nagahara et al.   NATURE REVIEWS DRUG DISCOVERY

Wallerian-like axonal degeneration in the optic nerve after excitotoxic retinal insult: an ultrastructural study

(2010) Sarabjit K Saggu et al.   BMC NEUROSCIENCE

CaMKII Autonomy Is Substrate-dependent and Further Stimulated by Ca2+/Calmodulin

(2010) Steven J. Coultrap et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autonomous CaMKII Can Promote either Long-Term Potentiation or Long-Term Depression, Depending on the State of T305/T306 Phosphorylation

(2010) H. J. Pi et al.   JOURNAL OF NEUROSCIENCE

Melanopsin-Expressing Retinal Ganglion-Cell Photoreceptors: Cellular Diversity and Role in Pattern Vision

(2010) Jennifer L. Ecker et al.   NEURON

CaMKII control of spine size and synaptic strength: Role of phosphorylation states and nonenzymatic action

(2010) H. J. Pi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective blockade of CaMKII-α inhibits NMDA-induced caspase-3-dependent cell death but does not arrest PARP-1 activation or loss of plasma membrane selectivity in rat retinal neurons

(2008) Dennis J. Goebel   BRAIN RESEARCH

Glutamatergic calcium dynamics and deregulation of rat retinal ganglion cells

(2008) Andrew T. E. Hartwick et al.   JOURNAL OF PHYSIOLOGY-LONDON

Promoting Axon Regeneration in the Adult CNS by Modulation of the PTEN/mTOR Pathway

(2008) K. K. Park et al.   SCIENCE