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Title
SLC7A11/xCT Prevents Cardiac Hypertrophy by Inhibiting Ferroptosis
Authors
Keywords
-
Journal
CARDIOVASCULAR DRUGS AND THERAPY
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-07-14
DOI
10.1007/s10557-021-07220-z
References
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Related references
Note: Only part of the references are listed.- Loss of Cardiac Ferritin H Facilitates Cardiomyopathy via Slc7a11-Mediated Ferroptosis
- (2020) Xuexian Fang et al. CIRCULATION RESEARCH
- The deubiquitinase UCHL1 regulates cardiac hypertrophy by stabilizing epidermal growth factor receptor
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- Pyroptosis and ferroptosis induced by mixed lineage kinase 3 (MLK3) signaling in cardiomyocytes are essential for myocardial fibrosis in response to pressure overload
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- Ferroptosis as a target for protection against cardiomyopathy
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- mTOR-dependent upregulation of xCT blocks melanin synthesis and promotes tumorigenesis
- (2019) Chunjia Li et al. CELL DEATH AND DIFFERENTIATION
- Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance
- (2019) Jonathan K. M. Lim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The immunoproteasome catalytic β5i subunit regulates cardiac hypertrophy by targeting the autophagy protein ATG5 for degradation
- (2019) Xin Xie et al. Science Advances
- Genetic Ablation of the Cystine Transporter xCT in PDAC Cells Inhibits mTORC1, Growth, Survival, and Tumor Formation via Nutrient and Oxidative Stresses
- (2019) Boutaina Daher et al. CANCER RESEARCH
- A new checkpoint against ferroptosis
- (2019) Deguang Liang et al. CELL RESEARCH
- Quantitative proteomic analyses reveal that GPX4 downregulation during myocardial infarction contributes to ferroptosis in cardiomyocytes
- (2019) Tae-Jun Park et al. Cell Death & Disease
- Protective effects of the mechanistic target of rapamycin against excess iron and ferroptosis in cardiomyocytes
- (2018) Yuichi Baba et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Metabolic Coordination of Physiological and Pathological Cardiac Remodeling
- (2018) Andrew A. Gibb et al. CIRCULATION RESEARCH
- The tumor suppressor protein p53 and the ferroptosis network
- (2018) Rui Kang et al. FREE RADICAL BIOLOGY AND MEDICINE
- PICK1 deficiency exacerbates sepsis-associated acute lung injury and impairs glutathione synthesis via reduction of xCT
- (2018) Meizi Qian et al. FREE RADICAL BIOLOGY AND MEDICINE
- The cystine-glutamate exchanger (xCT, Slc7a11) is expressed in significant concentrations in a subpopulation of astrocytes in the mouse brain
- (2018) Sigrid Ottestad-Hansen et al. GLIA
- Ferroptosis and Its Role in Diverse Brain Diseases
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- Characterization of ferroptosis in murine models of hemochromatosis
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- Hypertension, left ventricular hypertrophy, and sudden cardiac death
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- The glutamate/cystine xCT antiporter antagonizes glutamine metabolism and reduces nutrient flexibility
- (2017) Chun-Shik Shin et al. Nature Communications
- Cardiac structural remodeling in hypertensive cardiomyopathy
- (2016) Si-jia Sun et al. HYPERTENSION RESEARCH
- Ferroptosis: Death by Lipid Peroxidation
- (2016) Wan Seok Yang et al. TRENDS IN CELL BIOLOGY
- Temozolomide toxicity operates in a xCT/SLC7a11 dependent manner and is fostered by ferroptosis
- (2016) Tina Sehm et al. Oncotarget
- Inhibition of Hypertrophy Is a Good Therapeutic Strategy in Ventricular Pressure Overload
- (2015) G. G. Schiattarella et al. CIRCULATION
- The Cystine/Glutamate Antiporter System xc− in Health and Disease: From Molecular Mechanisms to Novel Therapeutic Opportunities
- (2012) Jan Lewerenz et al. ANTIOXIDANTS & REDOX SIGNALING
- The oxidative stress-inducible cystine/glutamate antiporter, system x c − : cystine supplier and beyond
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- Remodelling of the heart and vessels in experimental hypertension: advances in protection
- (2010) Fedor Simko et al. JOURNAL OF HYPERTENSION
- Aggravation of ischemia–reperfusion-triggered acute renal failure in xCT-deficient mice
- (2009) Tomohiro Shibasaki et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Angiotensin II-induced p53-dependent cardiac apoptotic cell death: Its prevention by metallothionein
- (2009) Qiuju Liu et al. TOXICOLOGY LETTERS
- The xc− cystine/glutamate antiporter: A potential target for therapy of cancer and other diseases
- (2008) Maisie Lo et al. JOURNAL OF CELLULAR PHYSIOLOGY
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