Dendrobium officinale polysaccharide triggers mitochondrial disorder to induce colon cancer cell death via ROS-AMPK-autophagy pathway

Cordyceps sinensis polysaccharide inhibits colon cancer cells growth by inducing apoptosis and autophagy flux blockage via mTOR signaling

(2020) Wucheng Qi et al.   CARBOHYDRATE POLYMERS

ATM ‐ CHK 2‐Beclin 1 axis promotes autophagy to maintain ROS homeostasis under oxidative stress

(2020) Qi‐Qiang Guo et al.   EMBO JOURNAL

Hierarchically constructed selenium-doped bone-mimetic nanoparticles promote ROS-mediated autophagy and apoptosis for bone tumor inhibition

(2020) Xiao Li et al.   BIOMATERIALS

The In Vitro and In Vivo Anticancer Properties of Chalcone Flavokawain B through Induction of ROS-Mediated Apoptotic and Autophagic Cell Death in Human Melanoma Cells

(2020) You-Cheng Hseu et al.   Cancers

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer

(2019) Kirsten L. Bryant et al.   NATURE MEDICINE

Dual roles of ULK1 (unc-51 like autophagy activating kinase 1) in cytoprotection against lipotoxicity

(2019) Jeong Su Park et al.   Autophagy

Polysaccharides as potential anticancer agents—A review of their progress

(2019) Tabassum Khan et al.   CARBOHYDRATE POLYMERS

Cancer treatment and survivorship statistics, 2019

(2019) Kimberly D. Miller et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Recent insights into apoptosis and toxic autophagy: the roles of MDA-7/IL-24, a multidimensional anti-cancer therapeutic

(2019) Luni Emdad et al.   SEMINARS IN CANCER BIOLOGY

Adrenomedullin alleviates the pyroptosis of Leydig cells by promoting autophagy via the ROS–AMPK–mTOR axis

(2019) Ming-yong Li et al.   Cell Death & Disease

Autophagic flux disruption contributes to Ganoderma lucidum polysaccharide-induced apoptosis in human colorectal cancer cells via MAPK/ERK activation

(2019) Haitao Pan et al.   Cell Death & Disease

Microvesicles: ROS scavengers and ROS producers

(2019) G. Bodega et al.   Journal of Extracellular Vesicles

Strategies for Colorectal Cancer Screening

(2019) Uri Ladabaum et al.   GASTROENTEROLOGY

Exopolysaccharides from Lactobacillus plantarum NCU116 Enhances Colonic Mucosal Homeostasis by Controlling Epithelial Cell Differentiation and c-Jun/Muc2 Signaling

(2019) Xingtao Zhou et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

SDHA gain-of-function engages inflammatory mitochondrial retrograde signaling via KEAP1–Nrf2

(2019) Anne-Valérie Burgener et al.   NATURE IMMUNOLOGY

Polyphyllin VI, a saponin from Trillium tschonoskii Maxim. induces apoptotic and autophagic cell death via the ROS triggered mTOR signaling pathway in non-small cell lung cancer

(2019) Jin-Feng Teng et al.   PHARMACOLOGICAL RESEARCH

Colorectal cancer

(2019) Evelien Dekker et al.   LANCET

A Diversity of Selective Autophagy Receptors Determines the Specificity of the Autophagy Pathway

(2019) Vladimir Kirkin et al.   MOLECULAR CELL

Mitochondria as multifaceted regulators of cell death

(2019) Florian J. Bock et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Dendrobium officinale polysaccharides alleviate colon tumorigenesis via restoring intestinal barrier function and enhancing anti-tumor immune response

(2019) Jian Liang et al.   PHARMACOLOGICAL RESEARCH

Mitochondria-acting nanomicelles for destruction of cancer cells via excessive mitophagy/autophagy-driven lethal energy depletion and phototherapy

(2019) Ya-Xuan Zhu et al.   BIOMATERIALS

FOXM1 contributes to docetaxel resistance in castration-resistant prostate cancer by inducing AMPK/mTOR-mediated autophagy

(2019) Jian-zhong Lin et al.   CANCER LETTERS

Chemical structure and anti-inflammatory effect of polysaccharide extracted from Morinda citrifolia Linn (Noni)

(2018) Stefany Guimarães Sousa et al.   CARBOHYDRATE POLYMERS

Biological activities and pharmaceutical applications of polysaccharide from natural resources: A review

(2018) Yue Yu et al.   CARBOHYDRATE POLYMERS

Calcium Signaling and Reactive Oxygen Species in Mitochondria

(2018) Edoardo Bertero et al.   CIRCULATION RESEARCH

Mitochondrial dynamics in adaptive and maladaptive cellular stress responses

(2018) Verónica Eisner et al.   NATURE CELL BIOLOGY

Functional polysaccharide Lentinan suppresses human breast cancer growth via inducing autophagy and caspase-7-mediated apoptosis

(2018) Weiyong Li et al.   Journal of Functional Foods

Targeted production of reactive oxygen species in mitochondria to overcome cancer drug resistance

(2018) Hai Wang et al.   Nature Communications

The pro-oxidant adaptor p66SHC promotes B cell mitophagy by disrupting mitochondrial integrity and recruiting LC3-II

(2018) Anna Onnis et al.   Autophagy

Mir223 restrains autophagy and promotes CNS inflammation by targeting ATG16L1

(2018) Yan Li et al.   Autophagy

The potential of fucose-containing sulfated polysaccharides as scaffolds for biomedical applications

(2018) Cláudia Nunes et al.   CURRENT MEDICINAL CHEMISTRY

Therapeutic effects of lentinan on inflammatory bowel disease and colitis-associated cancer

(2018) Yanrong Liu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mitochondrial energetics in the kidney

(2017) Pallavi Bhargava et al.   Nature Reviews Nephrology

Galactans: an overview of their most important sourcing and applications as natural polysaccharides

(2017) Cedric Delattre et al.   BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY

AMPK Promotes Autophagy by Facilitating Mitochondrial Fission

(2016) Chen-Song Zhang et al.   Cell Metabolism

An Autophagic Flux Probe that Releases an Internal Control

(2016) Takeshi Kaizuka et al.   MOLECULAR CELL

Cancer metabolism: a therapeutic perspective

(2016) Ubaldo E. Martinez-Outschoorn et al.   Nature Reviews Clinical Oncology

SOD2 and the Mitochondrial UPR: Partners Regulating Cellular Phenotypic Transitions

(2016) Chenxia He et al.   TRENDS IN BIOCHEMICAL SCIENCES

Study on Dendrobium officinale O -acetyl-glucomannan (Dendronan ® ): Part II. Fine structures of O -acetylated residues

(2015) Xiaohui Xing et al.   CARBOHYDRATE POLYMERS

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

A methanolic extract of Ganoderma lucidum fruiting body inhibits the growth of a gastric cancer cell line and affects cellular autophagy and cell cycle

(2014) Marta Oliveira et al.   Food & Function

Physiological Roles of Mitochondrial Reactive Oxygen Species

(2012) Laura A. Sena et al.   MOLECULAR CELL