TNPO1-mediated nuclear import of ARID1B promotes tumor growth in ARID1A-deficient gynecologic cancer

SWI/SNF Complex Mutations in Gynecologic Cancers: Molecular Mechanisms and Models

(2020) Yemin Wang et al.   Annual Review of Pathology-Mechanisms of Disease

AP-1 controls the p11-dependent antidepressant response

(2020) Revathy U. Chottekalapanda et al.   MOLECULAR PSYCHIATRY

Redox-dependent PPARγ/Tnpo1 complex formation enhances PPARγ nuclear localization and signaling

(2020) Toshiaki Teratani et al.   FREE RADICAL BIOLOGY AND MEDICINE

Re-expression of SMARCA4/BRG1 in small cell carcinoma of ovary, hypercalcemic type (SCCOHT) promotes an epithelial-like gene signature through an AP-1-dependent mechanism

(2020) Krystal Ann Orlando et al.   eLife

Differential role for phosphorylation in alternative polyadenylation function versus nuclear import of SR-like protein CPSF6

(2019) Sooin Jang et al.   NUCLEIC ACIDS RESEARCH

Chromatin remodellers Brg1 and Bptf are required for normal gene expression and progression of oncogenic Braf-driven mouse melanoma

(2019) Patrick Laurette et al.   CELL DEATH AND DIFFERENTIATION

HDAC6 inhibition synergizes with anti-PD-L1 therapy in ARID1A-inactivated ovarian cancer.

(2019) Takeshi Fukumoto et al.   CANCER RESEARCH

Altered nuclear export signal recognition as a driver of oncogenesis

(2019) Justin Taylor et al.   Cancer Discovery

ARID1A and PI3-kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion

(2019) Mike R. Wilson et al.   Nature Communications

ARID1A mutant ovarian clear cell carcinoma: A clear target for synthetic lethal strategies

(2018) Joseph J. Caumanns et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Karyopherins in cancer

(2018) Tolga Çağatay et al.   CURRENT OPINION IN CELL BIOLOGY

ARID1A mutation sensitizes most ovarian clear cell carcinomas to BET inhibitors

(2018) Katrien Berns et al.   ONCOGENE

ARID1A loss in cancer: Towards a mechanistic understanding

(2018) Radhika Mathur   PHARMACOLOGY & THERAPEUTICS

Nuclear import pathway key to rescuing dominant progerin phenotypes

(2018) Katherine L. Wilson   Science Signaling

Nuclear import pathway key to rescuing dominant progerin phenotypes

(2018) Katherine L. Wilson   Science Signaling

KPNA2 promotes metabolic reprogramming in glioblastomas by regulation of c-myc

(2018) Jie Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

SWI/SNF complex in cancer

(2017) Chao Lu et al.   NATURE GENETICS

CPSF6 is a Clinically Relevant Breast Cancer Vulnerability Target

(2017) Najat Binothman et al.   EBioMedicine

ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice

(2016) Radhika Mathur et al.   NATURE GENETICS

ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A

(2016) Chris T. Williamson et al.   Nature Communications

Nuclear localization signals for four distinct karyopherin-β nuclear import systems

(2015) Michael Soniat et al.   BIOCHEMICAL JOURNAL

Nuclear transport factors: global regulation of mitosis

(2015) Douglass J Forbes et al.   CURRENT OPINION IN CELL BIOLOGY

Arid1ainactivation in anApc- andPten-defective mouse ovarian cancer model enhances epithelial differentiation and prolongs survival

(2015) Yali Zhai et al.   JOURNAL OF PATHOLOGY

Genome-Wide Transcriptional Regulation Mediated by Biochemically Distinct SWI/SNF Complexes

(2015) Jesse R. Raab et al.   PLoS Genetics

Transportin-1 and Transportin-2: Protein nuclear import and beyond

(2014) Laure Twyffels et al.   FEBS LETTERS

ARID1B is a specific vulnerability in ARID1A-mutant cancers

(2014) Katherine C Helming et al.   NATURE MEDICINE

Snail nuclear transport: The gateways regulating epithelial-to-mesenchymal transition?

(2014) Irfana Muqbil et al.   SEMINARS IN CANCER BIOLOGY

Redox-Dependent Control of FOXO/DAF-16 by Transportin-1

(2013) Marrit Putker et al.   MOLECULAR CELL

ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import

(2010) Dorothee Dormann et al.   EMBO JOURNAL