Profile of sphingolipid-related genes and its association with prognosis highlights sphingolipid metabolism in oral cancer

Synergic effect of OP449 and FTY720 on oral squamous cell carcinoma

(2020) Renata Nishida Goto et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Targeting SET to restore PP2A activity disrupts an oncogenic CIP2A-feedforward loop and impairs triple negative breast cancer progression

(2019) Chun-Yu Liu et al.   EBioMedicine

Sphingomyelin Synthase 1 (SMS1) Downregulation Is Associated With Sphingolipid Reprogramming and a Worse Prognosis in Melanoma

(2019) Fatima Bilal et al.   Frontiers in Pharmacology

Sphingolipid/Ceramide Pathways and Autophagy in the Onset and Progression of Melanoma: Novel Therapeutic Targets and Opportunities

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ITGA5 inhibition in pancreatic stellate cells attenuates desmoplasia and potentiates efficacy of chemotherapy in pancreatic cancer

(2019) Praneeth R. Kuninty et al.   Science Advances

Sphingolipids in Non-Alcoholic Fatty Liver Disease and Hepatocellular Carcinoma: Ceramide Turnover

(2019) Jorge Simon et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

14-3-3ζ promotes esophageal squamous cell carcinoma invasion by repressing S1PR2 protein expression through NF-κB signaling

(2018) Song Tong et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Targeting the SphK1/S1P/S1PR1 Axis That Links Obesity, Chronic Inflammation, and Breast Cancer Metastasis

(2018) Masayuki Nagahashi et al.   CANCER RESEARCH

Survival benefit of sphingosin-1-phosphate and receptors expressions in breast cancer patients

(2018) Fu-Ju Lei et al.   Cancer Medicine

Alkaline ceramidase 3 promotes growth of hepatocellular carcinoma cells via regulating S1P/S1PR2/PI3K/AKT signaling

(2018) Yancun Yin et al.   PATHOLOGY RESEARCH AND PRACTICE

Sphingosine 1-phosphate (S1P) reduces hepatocyte growth factor-induced migration of hepatocellular carcinoma cells via S1P receptor 2

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Association Between Lymph Node Ratio and Recurrence and Survival Outcomes in Patients With Oral Cavity Cancer

(2018) Ding Ding et al.   JAMA Otolaryngology-Head & Neck Surgery

Metastatic Lymph Node Burden and Survival in Oral Cavity Cancer

(2017) Allen S. Ho et al.   JOURNAL OF CLINICAL ONCOLOGY

The Role of Sphingosine-1-Phosphate and Ceramide-1-Phosphate in Inflammation and Cancer

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ACER3 supports development of acute myeloid leukemia

(2016) Chen Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ceramide 1-phosphate regulates cell migration and invasion of human pancreatic cancer cells

(2016) Io-Guané Rivera et al.   BIOCHEMICAL PHARMACOLOGY

The hematopoietic oncoprotein FOXP1 promotes tumor cell survival in diffuse large B-cell lymphoma by repressing S1PR2 signaling

(2016) M. Flori et al.   BLOOD

An oncogenic role for sphingosine kinase 2

(2016) Heidi A. Neubauer et al.   Oncotarget

Head and neck solitary fibrous tumors: a rare and challenging entity

(2015) Julian Künzel et al.   EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY

Association of Drug Transporter Expression with Mortality and Progression-Free Survival in Stage IV Head and Neck Squamous Cell Carcinoma

(2014) Rolf Warta et al.   PLoS One

Critical Role of Spns2, a Sphingosine-1-Phosphate Transporter, in Lung Cancer Cell Survival and Migration

(2014) Eric Bradley et al.   PLoS One

The role of sphingosine kinase isoforms and receptors S1P1, S1P2, S1P3, and S1P5 in primary, secondary, and recurrent glioblastomas

(2014) Karl Quint et al.   TUMOR BIOLOGY

Sphingosine kinase/sphingosine 1-phosphate (S1P)/S1P receptor axis is involved in liver fibrosis-associated angiogenesis

(2013) Le Yang et al.   JOURNAL OF HEPATOLOGY

Spns2, a transporter of phosphorylated sphingoid bases, regulates their blood and lymph levels, and the lymphatic network

(2012) Masayuki Nagahashi et al.   FASEB JOURNAL

SET protein accumulates in HNSCC and contributes to cell survival: Antioxidant defense, Akt phosphorylation and AVOs acidification

(2012) Andréia M. Leopoldino et al.   ORAL ONCOLOGY

The Expression of Sphingosine Kinase-1 in Head and Neck Carcinoma

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Estradiol Induces Export of Sphingosine 1-Phosphate from Breast Cancer Cells via ABCC1 and ABCG2

(2010) Kazuaki Takabe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Spinster Homolog, Two of Hearts, Is Required for Sphingosine 1-Phosphate Signaling in Zebrafish

(2008) Nick Osborne et al.   CURRENT BIOLOGY