Selective inhibition of soluble TNF using XPro1595 relieves pain and attenuates cerulein-induced pathology in mice

Secretory Functions of Macrophages in the Human Pancreatic Islet Are Regulated by Endogenous Purinergic Signaling

(2020) Jonathan R. Weitz et al.   DIABETES

TNFR1 and TNFR2 in the Control of the Life and Death Balance of Macrophages

(2019) Harald Wajant et al.   Frontiers in Cell and Developmental Biology

Free Water in White Matter Differentiates MCI and AD From Control Subjects

(2019) Matthieu Dumont et al.   Frontiers in Aging Neuroscience

TNF-α mediated upregulation of NaV1.7 currents in rat dorsal root ganglion neurons is independent of CRMP2 SUMOylation

(2019) Flávio Henrique Pequeno de Macedo et al.   Molecular Brain

TNF-alpha and TNF-R1 regulate bupivacaine-induced apoptosis in spinal cord dorsal root ganglion neuron

(2018) Ke Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The neurobiology of acute pain

(2018) A. Bell   VETERINARY JOURNAL

Intrinsic TNFR2 signaling in T regulatory cells provides protection in CNS autoimmunity

(2018) Kamar-Sulu N. Atretkhany et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macrophage-derived HMGB1 as a Pain Mediator in the Early Stage of Acute Pancreatitis in Mice: Targeting RAGE and CXCL12/CXCR4 Axis

(2017) Yuhei Irie et al.   Journal of Neuroimmune Pharmacology

Peripheral administration of the soluble TNF inhibitor XPro1595 modifies brain immune cell profiles, decreases beta-amyloid plaque load, and rescues impaired long-term potentiation in 5xFAD mice

(2017) Kathryn P. MacPherson et al.   NEUROBIOLOGY OF DISEASE

Acute Pancreatitis: Etiology, Pathology, Diagnosis, and Treatment

(2017) Shirin Majidi et al.   SOUTHERN MEDICAL JOURNAL

Novel strategies to mimic transmembrane tumor necrosis factor-dependent activation of tumor necrosis factor receptor 2

(2017) Roman Fischer et al.   Scientific Reports

Loss of Periostin Results in Impaired Regeneration and Pancreatic Atrophy after Cerulein-Induced Pancreatitis

(2016) Simone Hausmann et al.   AMERICAN JOURNAL OF PATHOLOGY

Nucleotide-binding oligomerization domain 1 acts in concert with the cholecystokinin receptor agonist, cerulein, to induce IL-33-dependent chronic pancreatitis

(2016) T Watanabe et al.   Mucosal Immunology

Inhibiting tumor necrosis factor-α before amyloidosis prevents synaptic deficits in an Alzheimer's disease model

(2016) Chelsea Cavanagh et al.   NEUROBIOLOGY OF AGING

Metamizol Relieves Pain Without Interfering With Cerulein-Induced Acute Pancreatitis in Mice

(2016) Franziska Stumpf et al.   PANCREAS

EphrinB3 restricts endogenous neural stem cell migration after traumatic brain injury

(2016) Kirsty J. Dixon et al.   Stem Cell Research

Necrotizing pancreatitis: A review of the interventions

(2016) Walter Bugiantella et al.   International Journal of Surgery

Autophagy Inhibition Dysregulates TBK1 Signaling and Promotes Pancreatic Inflammation

(2016) S. Yang et al.   Cancer Immunology Research

Neuroinflammatory TNFα Impairs Memory via Astrocyte Signaling

(2015) Samia Habbas et al.   CELL

Endogenous Neural Stem/Progenitor Cells Stabilize the Cortical Microenvironment after Traumatic Brain Injury

(2015) Kirsty J. Dixon et al.   JOURNAL OF NEUROTRAUMA

Chronic constriction injury-induced nociception is relieved by nanomedicine-mediated decrease of rat hippocampal tumor necrosis factor

(2015) Elizabeth Gerard et al.   PAIN

Effect of Tumor Necrosis Factor–α Inhibitors on Drug-Induced Pancreatitis in Inflammatory Bowel Disease

(2014) Derrick J. Stobaugh et al.   ANNALS OF PHARMACOTHERAPY

Treatment of acute pancreatitis with protease inhibitors administered through intravenous infusion: an updated systematic review and meta-analysis

(2014) Takeshi Seta et al.   BMC GASTROENTEROLOGY

Neuropathic pain-induced depressive-like behavior and hippocampal neurogenesis and plasticity are dependent on TNFR1 signaling

(2014) Anna Dellarole et al.   BRAIN BEHAVIOR AND IMMUNITY

Systemically administered anti-TNF therapy ameliorates functional outcomes after focal cerebral ischemia

(2014) Bettina Hjelm Clausen et al.   Journal of Neuroinflammation

Cannabinoid Receptor 2 Agonist Attenuates Pain Related Behavior in Rats with Chronic Alcohol/High Fat Diet Induced Pancreatitis

(2014) Liping Zhang et al.   Molecular Pain

Immune-modulating therapy in acute pancreatitis: Fact or fiction

(2014) Karolina Akinosoglou   WORLD JOURNAL OF GASTROENTEROLOGY

American College of Gastroenterology Guideline: Management of Acute Pancreatitis

(2013) Scott Tenner et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Transient receptor potential ankyrin 1 mediates chronic pancreatitis pain in mice

(2013) Fiore Cattaruzza et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Antitumor Necrosis Factor Therapy Is Associated With Improved Survival in Clinical Sepsis Trials

(2013) Ping Qiu et al.   CRITICAL CARE MEDICINE

Anti-TNF Therapy in the Treatment of Psoriasis in a Patient with Acute-on-Chronic Pancreatitis

(2013) Helena Clayton et al.   DERMATOLOGY

Tumor Necrosis Factor in Traumatic Brain Injury: Effects of Genetic Deletion of p55 or p75 Receptor

(2013) Luca Longhi et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Reorganization of hippocampal functional connectivity with transition to chronic back pain

(2013) Amelia A. Mutso et al.   JOURNAL OF NEUROPHYSIOLOGY

Impaired Spatial Memory Performance in a Rat Model of Neuropathic Pain Is Associated with Reduced Hippocampus-Prefrontal Cortex Connectivity

(2013) H. Cardoso-Cruz et al.   JOURNAL OF NEUROSCIENCE

Increasing TNF levels solely in the rat hippocampus produces persistent pain-like symptoms

(2012) Regina T. Martuscello et al.   PAIN

Inhibition of Soluble Tumor Necrosis Factor Ameliorates Synaptic Alterations and Ca2+ Dysregulation in Aged Rats

(2012) Diana M. Sama et al.   PLoS One

Inhibition of soluble tumour necrosis factor is therapeutic in experimental autoimmune encephalomyelitis and promotes axon preservation and remyelination

(2011) Roberta Brambilla et al.   BRAIN

Blockade of TNF-α rapidly inhibits pain responses in the central nervous system

(2011) Andreas Hess et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic Analysis of the Role of Tumor Necrosis Factor Receptors in Functional Outcome after Traumatic Brain Injury in Mice

(2010) Jinsheng Yang et al.   JOURNAL OF NEUROTRAUMA

Tumor necrosis factor-α induces sensitization of meningeal nociceptors mediated via local COX and p38 MAP kinase actions

(2010) Xi-Chun Zhang et al.   PAIN

Selective death of autoreactive T cells in human diabetes by TNF or TNF receptor 2 agonism

(2008) L. Ban et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA