Optimization of CRISPR‐Cas9 through promoter replacement and efficient production of L‐homoserine in Corynebacterium glutamicum

Metabolic engineering of carbohydrate metabolism systems in Corynebacterium glutamicum for improving the efficiency of l-lysine production from mixed sugar

(2020) Jian-Zhong Xu et al.   Microbial Cell Factories

Crispr/Cas9‐mediated cleavages facilitate homologous recombination during genetic engineering of a large chromosomal region

(2020) Fan Zhang et al.   BIOTECHNOLOGY AND BIOENGINEERING

High-yield production of l-serine through a novel identified exporter combined with synthetic pathway in Corynebacterium glutamicum

(2020) Xiaomei Zhang et al.   Microbial Cell Factories

Significantly enhancing production of trans-4-hydroxy-l-proline by integrated system engineering in Escherichia coli

(2020) Mengfei Long et al.   Science Advances

Rational modification of the carbon metabolism of Corynebacterium glutamicum to enhance l-leucine production

(2020) Ying-Yu Wang et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Obtaining a series of native gradient promoter-5′-UTR sequences in Corynebacterium glutamicum ATCC 13032

(2020) Ning Li et al.   Microbial Cell Factories

De Novo Engineering of Corynebacterium glutamicum for l-Proline Production

(2020) Jiao Zhang et al.   ACS Synthetic Biology

Efficient production of L-homoserine in Corynebacterium glutamicum ATCC 13032 by redistribution of metabolic flux

(2020) Ning Li et al.   BIOCHEMICAL ENGINEERING JOURNAL

Metabolic engineering of an auto-regulated Corynebacterium glutamicum chassis for biosynthesis of 5-aminolevulinic acid

(2020) Chenglin Zhang et al.   BIORESOURCE TECHNOLOGY

Impaired oxidative stress and sulfur assimilation contribute to acid tolerance of Corynebacterium glutamicum

(2019) Ning Xu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Metabolic engineering of Corynebacterium glutamicum S9114 to enhance the production of ʟ-ornithine driven by glucose and xylose

(2019) Bin Zhang et al.   BIORESOURCE TECHNOLOGY

Increasing the specificity of CRISPR systems with engineered RNA secondary structures

(2019) D. Dewran Kocak et al.   NATURE BIOTECHNOLOGY

Xylose as preferred substrate for sarcosine production by recombinant Corynebacterium glutamicum

(2019) Melanie Mindt et al.   BIORESOURCE TECHNOLOGY

A CRISPR–Cas9 system for multiple genome editing and pathway assembly in Candida tropicalis

(2019) Lihua Zhang et al.   BIOTECHNOLOGY AND BIOENGINEERING

A CRISPR/Cas9-based genome editing system for Rhodococcus ruber TH

(2019) Youxiang Liang et al.   METABOLIC ENGINEERING

Synthetic Escherichia coli - Corynebacterium glutamicum consortia for l- lysine production from starch and sucrose

(2018) Elvira Sgobba et al.   BIORESOURCE TECHNOLOGY

Lysine production from the sugar alcohol mannitol: Design of the cell factory Corynebacterium glutamicum SEA-3 through integrated analysis and engineering of metabolic pathway fluxes

(2018) Sarah Lisa Hoffmann et al.   METABOLIC ENGINEERING

Metabolic engineering to guide evolution – Creating a novel mode for L -valine production with Corynebacterium glutamicum

(2018) Andreas Schwentner et al.   METABOLIC ENGINEERING

A RecET-assisted CRISPR–Cas9 genome editing in Corynebacterium glutamicum

(2018) Bo Wang et al.   Microbial Cell Factories

Reprogramming One-Carbon Metabolic Pathways To Decouple l-Serine Catabolism from Cell Growth in Corynebacterium glutamicum

(2018) Yun Zhang et al.   ACS Synthetic Biology

T7 Polymerase Expression of Guide RNAs in vivo Allows Exportable CRISPR-Cas9 Editing in Multiple Yeast Hosts

(2018) Nicholas J. Morse et al.   ACS Synthetic Biology

A CRISPR-Cpf1-Assisted Non-Homologous End Joining Genome Editing System of Mycobacterium smegmatis

(2018) Bingbing Sun et al.   Biotechnology Journal

CRISPR/Cas9-coupled recombineering for metabolic engineering of Corynebacterium glutamicum

(2017) Jae Sung Cho et al.   METABOLIC ENGINEERING

Development of a CRISPR/Cas9 genome editing toolbox for Corynebacterium glutamicum

(2017) Jiao Liu et al.   Microbial Cell Factories

Efficient gene editing in Corynebacterium glutamicum using the CRISPR/Cas9 system

(2017) Feng Peng et al.   Microbial Cell Factories

Recombineering using RecET in Corynebacterium glutamicum ATCC14067 via a self-excisable cassette

(2017) Yuanyuan Huang et al.   Scientific Reports

Multigene Editing in the Escherichia coli Genome via the CRISPR-Cas9 System

(2015) Yu Jiang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

An efficient blue-white screening based gene inactivation system for Streptomyces

(2015) Pengwei Li et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Structure and specificity of the RNA-guided endonuclease Cas9 during DNA interrogation, target binding and cleavage

(2015) Eric A. Josephs et al.   NUCLEIC ACIDS RESEARCH

Development of a markerless gene replacement system in Corynebacterium glutamicum using upp as a counter-selection marker

(2014) Wenwen Ma et al.   BIOTECHNOLOGY LETTERS

Guide RNA Functional Modules Direct Cas9 Activity and Orthogonality

(2014) Alexandra E. Briner et al.   MOLECULAR CELL

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

(2014) Yanfang Fu et al.   NATURE BIOTECHNOLOGY

Isolation of fully synthetic promoters for high-level gene expression inCorynebacterium glutamicum

(2013) Sung Sun Yim et al.   BIOTECHNOLOGY AND BIOENGINEERING

Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems

(2013) James E. DiCarlo et al.   NUCLEIC ACIDS RESEARCH

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Full-length RecE enhances linear-linear homologous recombination and facilitates direct cloning for bioprospecting

(2012) Jun Fu et al.   NATURE BIOTECHNOLOGY

Metabolic engineering and flux analysis of Corynebacterium glutamicum for L-serine production

(2012) ShuJuan Lai et al.   Science China-Life Sciences

Efficient markerless gene replacement in Corynebacterium glutamicum using a new temperature-sensitive plasmid

(2011) Naoko Okibe et al.   JOURNAL OF MICROBIOLOGICAL METHODS

A Role of thecspAGene Encoding a Mycolyltransferase in the Growth under Alkaline Conditions ofCorynebacterium glutamicum

(2010) Ryo TAKESHITA et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

The serine hydroxymethyltransferase gene glyA in Corynebacterium glutamicum is controlled by GlyR

(2008) Jens-Eric Schweitzer et al.   JOURNAL OF BIOTECHNOLOGY