Single and double modified salinomycin analogs target stem-like cells in 2D and 3D breast cancer models

Antibacterial activity of singly and doubly modified salinomycin derivatives

(2020) Michał Sulik et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Salinomycin Derivatives Kill Breast Cancer Stem Cells via Lysosomal Iron Targeting

(2020) Antoine Versini et al.   CHEMISTRY-A EUROPEAN JOURNAL

Carbamate derivatives of colchicine show potent activity towards primary acute lymphoblastic leukemia and primary breast cancer cells—in vitro and ex vivo study

(2020) Alicja Urbaniak et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Overcoming Resistance to Platinum-Based Drugs in Ovarian Cancer by Salinomycin and Its Derivatives—An In Vitro Study

(2020) Marcin Michalak et al.   MOLECULES

CD44 regulates epigenetic plasticity by mediating iron endocytosis

(2020) Sebastian Müller et al.   Nature Chemistry

Salinomycin Treatment Specifically Inhibits Cell Proliferation of Cancer Stem Cells Revealed by Longitudinal Single Cell Tracking in Combination with Fluorescence Microscopy

(2020) Sofia Kamlund et al.   Applied Sciences-Basel

Breast tumour organoids: promising models for the genomic and functional characterisation of breast cancer

(2019) Charlotte Roelofs et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Salinomycin inhibits breast cancer progression via targeting HIF-1α/VEGF mediated tumor angiogenesis in vitro and in vivo

(2019) Jayant Dewangan et al.   BIOCHEMICAL PHARMACOLOGY

Anti-trypanosomal activity of doubly modified salinomycin derivatives

(2019) Michał Antoszczak et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The response of phyllodes tumor of the breast to anticancer therapy: An in vitro and ex�vivo study

(2019) Alicja Urbaniak et al.   Oncology Letters

Synthesis and Anticancer Activity of Tertiary Amides of Salinomycin and Their C20‐oxo Analogues

(2019) Dominika Czerwonka et al.   ChemMedChem

CLASTR: The Cellosaurus STR similarity search tool ‐ A precious help for cell line authentication

(2019) Thibault Robin et al.   INTERNATIONAL JOURNAL OF CANCER

Salinomycin effectively eliminates cancer stem-like cells and obviates hepatic metastasis in uveal melanoma

(2019) Jingfeng Zhou et al.   Molecular Cancer

A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity

(2019) Fadi Jacob et al.   CELL

Dual Antibacterial and Anticancer Activity of 4-Benzoyl-1-dichlorobenzoylthiosemicarbazide Derivatives

(2018) Barbara Kapron et al.   Anti-Cancer Agents in Medicinal Chemistry

Semi-synthetic salinomycin analogs exert cytotoxic activity against human colorectal cancer stem cells

(2018) Johannes Klose et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Salinomycin derivatives exhibit activity against primary acute lymphoblastic leukemia (ALL) cells in vitro

(2018) Alicja Urbaniak et al.   BIOMEDICINE & PHARMACOTHERAPY

A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity

(2018) Norman Sachs et al.   CELL

Biological activity of doubly modified salinomycin analogs – Evaluation in vitro and ex vivo

(2018) Michał Antoszczak et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Chemical biology of salinomycin

(2018) Antoine Versini et al.   TETRAHEDRON

Epidemiological patterns of leukaemia in 184 countries: a population-based study

(2018) Adalberto Miranda-Filho et al.   Lancet Haematology

The Molecular Basis for Inhibition of Stemlike Cancer Cells by Salinomycin

(2018) Xiaoli Huang et al.   ACS Central Science

Salinomycin suppresses cancer cell stemness and attenuates TGF-β-induced epithelial-mesenchymal transition of renal cell carcinoma cells

(2018) Lei Liu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Salinomycin kills cancer stem cells by sequestering iron in lysosomes

(2017) Trang Thi Mai et al.   Nature Chemistry

Salinomycin: A new paradigm in cancer therapy

(2017) Jayant Dewangan et al.   TUMOR BIOLOGY

Human engineered heart tissue as a model system for drug testing

(2016) Alexandra Eder et al.   ADVANCED DRUG DELIVERY REVIEWS

Breast cancer stem cell selectivity of synthetic nanomolar-active salinomycin analogs

(2016) Xiaoli Huang et al.   BMC CANCER

Cell Cycle-Dependent Mechanisms Underlie Vincristine-Induced Death of Primary Acute Lymphoblastic Leukemia Cells

(2016) A. Kothari et al.   CANCER RESEARCH

Cancer stem cell drugs target K-ras signaling in a stemness context

(2016) A K Najumudeen et al.   ONCOGENE

In vitro activity of salinomycin and monensin derivatives against Trypanosoma brucei

(2016) Dietmar Steverding et al.   Parasites & Vectors

Salinomycin Hydroxamic Acids: Synthesis, Structure, and Biological Activity of Polyether Ionophore Hybrids

(2016) Björn Borgström et al.   ACS Medicinal Chemistry Letters

Targeting breast cancer stem cells in triple-negative breast cancer using a combination of LBH589 and salinomycin

(2015) Masaya Kai et al.   BREAST CANCER RESEARCH AND TREATMENT

Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver

(2015) Meritxell Huch et al.   CELL

New Findings on Breast Cancer Stem Cells: A Review

(2015) Azam Bozorgi et al.   Journal of Breast Cancer

Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis

(2015) Minoru Takasato et al.   NATURE

Salinomycin inhibits the growth of colorectal carcinoma by targeting tumor stem cells

(2015) CHEN ZHANG et al.   ONCOLOGY REPORTS

Salinomycin Promotes Anoikis and Decreases the CD44+/CD24- Stem-Like Population via Inhibition of STAT3 Activation in MDA-MB-231 Cells

(2015) Hyunsook An et al.   PLoS One

Semisynthesis of SY-1 for Investigation of Breast Cancer Stem Cell Selectivity of C-Ring-Modified Salinomycin Analogues

(2014) Xiaoli Huang et al.   ACS Chemical Biology

Synthesis, antiproliferative and antibacterial activity of new amides of salinomycin

(2014) Michał Antoszczak et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The pro-apoptotic role of autophagy in breast cancer

(2014) S Suman et al.   BRITISH JOURNAL OF CANCER

Synthesis, cytotoxicity and antibacterial activity of new esters of polyether antibiotic – salinomycin

(2014) Michał Antoszczak et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Salinomycin treatment reduces metastatic tumor burden by hampering cancer cell migration

(2014) Florian Kopp et al.   Molecular Cancer

Synthesis, Anticancer and Antibacterial Activity of Salinomycin N-Benzyl Amides

(2014) Michał Antoszczak et al.   MOLECULES

Understanding and targeting cancer stem cells: therapeutic implications and challenges

(2013) Ke Chen et al.   ACTA PHARMACOLOGICA SINICA

Salinomycin induces activation of autophagy, mitophagy and affects mitochondrial polarity: Differences between primary and cancer cells

(2013) Jaganmohan Reddy Jangamreddy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Synthetic modification of salinomycin: selective O-acylation and biological evaluation

(2013) Björn Borgström et al.   CHEMICAL COMMUNICATIONS

Interconnections between apoptotic, autophagic and necrotic pathways: implications for cancer therapy development

(2013) Mayur V. Jain et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Synthesis and antimicrobial activity of amide derivatives of polyether antibiotic—salinomycin

(2012) Adam Huczyński et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Salinomycin as a Drug for Targeting Human Cancer Stem Cells

(2012) Cord Naujokat et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Sphingolipids: regulators of crosstalk between apoptosis and autophagy

(2012) Megan M. Young et al.   JOURNAL OF LIPID RESEARCH

X-ray, FT-IR, NMR and PM5 structural studies and antibacterial activity of unexpectedly stable salinomycin–benzotriazole intermediate ester

(2012) Adam Huczyński et al.   JOURNAL OF MOLECULAR STRUCTURE

Salinomycin inhibits osteosarcoma by targeting its tumor stem cells

(2011) Qing-Lian Tang et al.   CANCER LETTERS

Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells

(2011) Desheng Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

(2010) T.-C. Chou   CANCER RESEARCH

Three-dimensional culture of hepatocytes for prediction of drug-induced hepatotoxicity

(2010) Qin Meng   Expert Opinion on Drug Metabolism & Toxicology

Autophagy: cellular and molecular mechanisms

(2010) Danielle Glick et al.   JOURNAL OF PATHOLOGY

Eaten alive: a history of macroautophagy

(2010) Zhifen Yang et al.   NATURE CELL BIOLOGY

Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

(2009) Piyush B. Gupta et al.   CELL

Enhancement of Docetaxel Anticancer Activity by a Novel Diindolylmethane Compound in Human Non-Small Cell Lung Cancer

(2009) N. Ichite et al.   CLINICAL CANCER RESEARCH

Long–term culture of primary human lymphoblastic leukemia cells in the absence of serum or hematopoietic growth factors

(2009) Bart A. Nijmeijer et al.   EXPERIMENTAL HEMATOLOGY

Autophagic cell death: the story of a misnomer

(2008) Guido Kroemer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Generation of Breast Cancer Stem Cells through Epithelial-Mesenchymal Transition

(2008) Anne-Pierre Morel et al.   PLoS One