Recovery of post-stroke cognitive and motor deficiencies by Shuxuening injection via regulating hippocampal BDNF-mediated Neurotrophin/Trk Signaling

Bone marrow mesenchymal stem cell-derived exosomes attenuate cerebral ischemia-reperfusion injury-induced neuroinflammation and pyroptosis by modulating microglia M1/M2 phenotypes

(2021) Xiaoli Liu et al.   EXPERIMENTAL NEUROLOGY

Heart Disease and Stroke Statistics—2020 Update: A Report From the American Heart Association

(2020) Salim S. Virani et al.   CIRCULATION

Bungeanum Improves Cognitive Dysfunction and Neurological Deficits in D-Galactose-Induced Aging Mice via Activating PI3K/Akt/Nrf2 Signaling Pathway

(2020) Meihuan Zhao et al.   Frontiers in Pharmacology

Protection against acute cerebral ischemia/reperfusion injury by QiShenYiQi via neuroinflammatory network mobilization

(2020) Yule Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Endothelium-Targeted Deletion of microRNA-15a/16-1 Promotes Poststroke Angiogenesis and Improves Long-Term Neurological Recovery

(2020) Ping Sun et al.   CIRCULATION RESEARCH

Icariside II, a PDE5 Inhibitor, Suppresses Oxygen-Glucose Deprivation/Reperfusion-Induced Primary Hippocampal Neuronal Death Through Activating the PKG/CREB/BDNF/TrkB Signaling Pathway

(2020) Fan Xu et al.   Frontiers in Pharmacology

Shuxuening injection facilitates neurofunctional recovery via down-regulation of G-CSF-mediated granulocyte adhesion and diapedesis pathway in a subacute stroke mouse model

(2020) Zhixiong Li et al.   BIOMEDICINE & PHARMACOTHERAPY

A1 astrocytes contribute to murine depression-like behavior and cognitive dysfunction, which can be alleviated by IL-10 or fluorocitrate treatment

(2020) He-Yang Zhang et al.   Journal of Neuroinflammation

Blockade of HCN2 Channels Provides Neuroprotection Against Ischemic Injury via Accelerating Autophagic Degradation in Hippocampal Neurons

(2020) Cheng Chen et al.   Neuroscience Bulletin

The physiology of regulated BDNF release

(2020) Tanja Brigadski et al.   CELL AND TISSUE RESEARCH

A strategy for identifying effective and risk compounds of botanical drugs with LC-QTOF-MS and network analysis: A case study of Ginkgo biloba preparation

(2020) Yi Zhong et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Stroke promotes the development of brain atrophy and delayed cell death in hypertensive rats

(2020) Mohammed A. Sayed et al.   Scientific Reports

Learning and memory deficits and Alzheimer's disease-like changes in mice after chronic exposure to microcystin-LR

(2019) Jing Wang et al.   JOURNAL OF HAZARDOUS MATERIALS

Setting the scene for the Second Stroke Recovery and Rehabilitation Roundtable

(2019) Julie Bernhardt et al.   International Journal of Stroke

Integrated liquid chromatography-mass spectrometry and nuclear magnetic resonance spectra for the comprehensive characterization of various components in the Shuxuening injection

(2019) Shuting Yu et al.   JOURNAL OF CHROMATOGRAPHY A

Prevention of excitotoxicity‐induced processing of BDNF receptor TrkB‐FL leads to stroke neuroprotection

(2019) Gonzalo S Tejeda et al.   EMBO Molecular Medicine

Andrographolide enhances hippocampal BDNF signaling and suppresses neuronal apoptosis, astroglial activation, neuroinflammation, and spatial memory deficits in a rat model of chronic cerebral hypoperfusion

(2019) Da-Peng Wang et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Stem cell factor and granulocyte colony-stimulating factor promote brain repair and improve cognitive function through VEGF-A in a mouse model of CADASIL

(2019) Suning Ping et al.   NEUROBIOLOGY OF DISEASE

Ginkgo Flavonol Glycosides or Ginkgolides Tend to Differentially Protect Myocardial or Cerebral Ischemia–Reperfusion Injury via Regulation of TWEAK-Fn14 Signaling in Heart and Brain

(2019) Guangxu Xiao et al.   Frontiers in Pharmacology

Cognition in stroke rehabilitation and recovery research: Consensus-based core recommendations from the second Stroke Recovery and Rehabilitation Roundtable

(2019) Matthew W McDonald et al.   International Journal of Stroke

Pseudoginsenoside-F11 improves long-term neurological function and promotes neurogenesis after transient cerebral ischemia in mice

(2019) Linlin Yuan et al.   NEUROCHEMISTRY INTERNATIONAL

Differential effects of transient and sustained activation of BDNF-TrkB signaling

(2018) Wei Guo et al.   Developmental Neurobiology

Exercise Rehabilitation Attenuates Cognitive Deficits in Rats with Traumatic Brain Injury by Stimulating the Cerebral HSP20/BDNF/TrkB Signalling Axis

(2018) Willy Chou et al.   MOLECULAR NEUROBIOLOGY

Tnfrsf12a-Mediated Atherosclerosis Signaling and Inflammatory Response as a Common Protection Mechanism of Shuxuening Injection Against Both Myocardial and Cerebral Ischemia-Reperfusion Injuries

(2018) Ming Lyu et al.   Frontiers in Pharmacology

Ginkgo biloba Extract Inhibits Astrocytic Lipocalin-2 Expression and Alleviates Neuroinflammatory Injury via the JAK2/STAT3 Pathway After Ischemic Brain Stroke

(2018) Yehao Zhang et al.   Frontiers in Pharmacology

Post-stroke inflammation—target or tool for therapy?

(2018) Kate Lykke Lambertsen et al.   ACTA NEUROPATHOLOGICA

Actions of Brain-Derived Neurotrophin Factor in the Neurogenesis and Neuronal Function, and Its Involvement in the Pathophysiology of Brain Diseases

(2018) Tadahiro Numakawa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Agreed definitions and a shared vision for new standards in stroke recovery research: The Stroke Recovery and Rehabilitation Roundtable taskforce

(2017) Julie Bernhardt et al.   International Journal of Stroke

Neurotrophic factors in Alzheimer's and Parkinson's diseases: implications for pathogenesis and therapy

(2017) Simone Pinton et al.   Neural Regeneration Research

Neuroprotective action of N-acetyl serotonin in oxidative stress-induced apoptosis through the activation of both TrkB/CREB/BDNF pathway and Akt/Nrf2/Antioxidant enzyme in neuronal cells

(2017) Jae-Myung Yoo et al.   Redox Biology

Neurotrophin signalling: novel insights into mechanisms and pathophysiology

(2016) M. Mitre et al.   CLINICAL SCIENCE

Relationship of circulatory BDNF with cognitive deficits in people with Parkinson's disease

(2016) Hanan Khalil et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Inflammation and Stroke: An Overview

(2016) Josef Anrather et al.   Neurotherapeutics

Low BDNF is associated with cognitive impairments in patients with Parkinson’s disease

(2016) Yu Wang et al.   PARKINSONISM & RELATED DISORDERS

Rapid erasure of hippocampal memory following inhibition of dentate gyrus granule cells

(2016) Noelia Madroñal et al.   Nature Communications

ESC-Derived BDNF-Overexpressing Neural Progenitors Differentially Promote Recovery in Huntington's Disease Models by Enhanced Striatal Differentiation

(2016) Tina Zimmermann et al.   Stem Cell Reports

Trajectory of Cognitive Decline After Incident Stroke

(2015) Deborah A. Levine et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

TrkB/BDNF signalling patterns the sympathetic nervous system

(2015) Jennifer C. Kasemeier-Kulesa et al.   Nature Communications

An Adaptive Role for BDNF Val66Met Polymorphism in Motor Recovery in Chronic Stroke

(2014) L. Qin et al.   JOURNAL OF NEUROSCIENCE

Transport of ginkgolides with different lipophilicities based on an hCMEC/D3 cell monolayer as a blood–brain barrier cell model

(2014) Shuwei Ma et al.   LIFE SCIENCES

Chondroitinase Enhances Cortical Map Plasticity and Increases Functionally Active Sprouting Axons after Brain Injury

(2013) Neil G. Harris et al.   JOURNAL OF NEUROTRAUMA

Heme Oxygenase 1-Mediated Neurogenesis Is Enhanced by Ginkgo biloba (EGb 761®) After Permanent Ischemic Stroke in Mice

(2013) Shadia E. Nada et al.   MOLECULAR NEUROBIOLOGY

Systemic Delivery of Recombinant Brain Derived Neurotrophic Factor (BDNF) in the R6/2 Mouse Model of Huntington’s Disease

(2013) Carmela Giampà et al.   PLoS One

Assessing the Temporal Relationship Between Cognition and Gait: Slow Gait Predicts Cognitive Decline in the Mayo Clinic Study of Aging

(2012) M. M. Mielke et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Neurotrophin regulation of neural circuit development and function

(2012) Hyungju Park et al.   NATURE REVIEWS NEUROSCIENCE

c-Jun Reprograms Schwann Cells of Injured Nerves to Generate a Repair Cell Essential for Regeneration

(2012) Peter J. Arthur-Farraj et al.   NEURON

Ginkgo biloba extract attenuates hippocampal neuronal loss and cognitive dysfunction resulting from trimethyltin in mice

(2012) Sukhwinder Kaur et al.   PHYTOMEDICINE

TrkB inhibition as a therapeutic target for CNS-related disorders

(2012) Fabien Boulle et al.   PROGRESS IN NEUROBIOLOGY

Prevalence of Poststroke Cognitive Impairment

(2012) Abdel Douiri et al.   STROKE

Brain-Derived Neurotrophic Factor: A Dynamic Gatekeeper of Neural Plasticity

(2012) Kiriana Cowansage et al.   Current Molecular Pharmacology

Current therapies in ischemic stroke. Part A. Recent developments in acute stroke treatment and in stroke prevention

(2011) Erasmia Broussalis et al.   DRUG DISCOVERY TODAY

Epigenetic regulation of the BDNF gene: implications for psychiatric disorders

(2011) F Boulle et al.   MOLECULAR PSYCHIATRY

Distinct pattern separation related transfer functions in human CA3/dentate and CA1 revealed using high-resolution fMRI and variable mnemonic similarity

(2010) J. W. Lacy et al.   LEARNING & MEMORY

Blood brain barrier permeability and therapeutic time window of Ginkgolide B in ischemia–reperfusion injury

(2009) Weirong Fang et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Brain-derived neurotrophic factor in neurodegenerative diseases

(2009) Chiara Zuccato et al.   Nature Reviews Neurology

Gait Dysfunction in Mild Cognitive Impairment Syndromes

(2008) Joe Verghese et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Differential roles for hippocampal areas CA1 and CA3 in the contextual encoding and retrieval of extinguished fear

(2008) J. Ji et al.   LEARNING & MEMORY

Brain Derived Neurotrophic Factor (BDNF) Contributes to the Pain Hypersensitivity Following Surgical Incision in the Rats

(2008) Chang-Qi Li et al.   Molecular Pain